Page last updated: 2024-11-07

methylprednisolone acetate and Carpal Tunnel Syndrome

methylprednisolone acetate has been researched along with Carpal Tunnel Syndrome in 12 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Carpal Tunnel Syndrome: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Research Excerpts

ExcerptRelevanceReference
"double steroid injections in the treatment of carpal tunnel syndrome (CTS) in a randomised double-blind controlled trial."2.71Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial. ( Chiu, JH; Hui, AC; Lo, SK; Poon, WF; Wong, L; Wong, SM, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chesterton, LS2
Blagojevic-Bucknall, M2
Burton, C2
Dziedzic, KS2
Davenport, G2
Jowett, SM1
Myers, HL2
Oppong, R1
Rathod-Mistry, T1
van der Windt, DA2
Hay, EM2
Roddy, E2
Kamel, SR1
Sadek, HA1
Hamed, A1
Sayed, OA1
Mahmud, MH1
Mohamed, FA1
El Sagher, GM1
Aly, LH1
Rathod, T1
Jowet, SM1
Badarny, S1
Rawashdeh, H1
Meer, J1
Abed, S1
Habib, G1
Park, GY1
Kim, SK1
Park, JH1
Hui, AC2
Wong, SM2
Tang, A1
Mok, V1
Hung, LK1
Wong, KS1
Agarwal, V1
Singh, R1
Sachdev, A1
Shekhar, S1
Goel, D1
Lo, SK1
Chiu, JH1
Poon, WF1
Wong, L1
Nalamachu, S1
Crockett, RS1
Mathur, D1
Tavares, SP1
Giddins, GE1
Mondelli, M1
Porta, PD1
Zalaffi, A1
Rossi, A1
Celiker, R1
Arslan, S1
Inanici, F1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised, Multicentre, Open Label, Parallel Group Pragmatic Clinical Trial of Local Steroid Injection Versus Night Splinting in Mild to Moderate Carpal Tunnel Syndrome (CTS)[NCT02038452]Phase 4234 participants (Actual)Interventional2014-04-30Completed
The Use of N-acetylcysteine Supplementation in Addition to Night Splinting for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized, Double-blind, Placebo-controlled Trial[NCT04460521]Phase 4240 participants (Anticipated)Interventional2021-08-01Recruiting
A Prospective, Randomized, Double-Blind, Cross-over Study of Lidocaine Patch 1.8% in Patients With Moderate to Severe Pain From Carpal Tunnel Syndrome[NCT04245371]Phase 445 participants (Actual)Interventional2020-02-24Completed
Randomized Controlled Trial of Ultrasound-guided Steroid Injection Versus Wrist Splint in Patients With Carpal Tunnel Syndrome[NCT04515966]Phase 470 participants (Anticipated)Interventional2020-12-01Recruiting
The Therapeutic Effect and Quality of Life After Local Injection of Steroid VS. Glucose 5% for Carpal Tunnel Syndrome : Double-blinded Clinical Trial[NCT05496764]Phase 452 participants (Anticipated)Interventional2021-12-01Recruiting
Combined Effect of Insulin and Sodium Hyaluronate Injection Guided by Ultrasound in Carpal Tunnel Syndrome[NCT04142411]Early Phase 190 participants (Anticipated)Interventional2019-11-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

BCTQ Functional Limitations Subscale 6 Months

Comparison of BCTQ functional limitations between treatment groups at 6 months follow-up (1-5 scale, higher score indicates more functional impairment). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection1.91
Wrist Splint1.89

BCTQ Functional Limitations Subscale 6 Months (CC)

Sensitivity analysis for comparison of BCTQ function limitations between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection1.85
Wrist Splint1.88

BCTQ Functional Limitations Subscale 6 Months (PP)

Per protocol analysis for comparison of BCTQ functional limitations between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection1.89
Wrist Splint1.84

BCTQ Functional Limitations Subscale 6 Weeks

Comparison of BCTQ functional limitations between treatment groups at 6 weeks follow-up (1-5 scale, higher score indicates more severe functional impairment). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.88
Wrist Splint2.09

BCTQ Functional Limitations Subscale 6 Weeks (CC)

Sensitivity analysis for comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.86
Wrist Splint2.10

BCTQ Functional Limitations Subscale 6 Weeks (PP)

"Per protocol analysis for comparison of BCTQ functional limitations between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more functional impairment) on participants with complete data.~BCTQ: Boston Carpal Tunnel Questionnaire" (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.88
Wrist Splint2.06

BCTQ Symptom Severity and Functional Limitations 6 Months

Comparison of overall BCTQ between treatment groups at 6 months follow-up (1-5 scale, higher score indicates more severe symptoms and functional impairment). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.15
Wrist Splint2.06

BCTQ Symptom Severity and Functional Limitations 6 Months (CC)

Sensitivity analysis for comparison of overall BCTQ between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.08
Wrist Splint2.04

BCTQ Symptom Severity and Functional Limitations 6 Months (PP)

Per protocol analysis for comparison of overall BCTQ between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.09
Wrist Splint2.02

BCTQ Symptom Severity and Functional Limitations 6 Weeks (Complete Case Analysis (CC))

Sensitivity analysis for comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.95
Wrist Splint2.29

BCTQ Symptom Severity and Functional Limitations 6 Weeks (Per-Protocol Analysis (PP))

Per protocol analysis for comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.96
Wrist Splint2.28

BCTQ Symptom Severity and Functional Limitations 6 Weeks (SG, Did Not Receive the Intervention of Their Preference)

Subgroup analysis was performed in patients who did not receive the intervention of their preference. Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.15
Wrist Splint2.40

BCTQ Symptom Severity and Functional Limitations 6 Weeks (SG, Did Not State a Preference of Intervention)

Subgroup analysis was performed in patients who did not state a preference of intervention. Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.03
Wrist Splint2.26

BCTQ Symptom Severity and Functional Limitations 6 Weeks (SG, Preferred Injection)

Subgroup analysis was performed in patients who preferred injection. Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.88
Wrist Splint2.40

BCTQ Symptom Severity and Functional Limitations 6 Weeks (SG, Preferred Splint)

Subgroup analysis was performed in patients who preferred splint. Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.15
Wrist Splint2.40

BCTQ Symptom Severity and Functional Limitations 6 Weeks (Subgroup Analysis (SG), Intervention of Their Preference)

Subgroup analysis was performed in patients who were allocated the intervention of their preference. Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment) on participants with complete data. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.88
Wrist Splint2.19

BCTQ Symptom Severity and Functional Limitations Over 24 Months: 12 Months

Comparison of overall BCTQ between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 1-5, higher score indicates more severe symptoms and functional impairment). Results are presented at 12 months. BCTQ: Boston Carpal Tunnel Questionnaire. (NCT02038452)
Timeframe: 12 months

Interventionscore on a scale (Mean)
Steroid Injection1.98
Wrist Splint2.05

BCTQ Symptom Severity and Functional Limitations Over 24 Months: 6 Months

Comparison of overall BCTQ between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up. Scale 1-5, higher score indicates more severe symptoms and functional impairment. Results are presented at 6 months. BCTQ: Boston Carpal Tunnel Questionnaire. (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.08
Wrist Splint2.04

BCTQ Symptom Severity and Functional Limitations Over 24 Months: 6 Weeks

Comparison of overall BCTQ between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 1-5, higher score indicates more severe symptoms and functional impairment. Results are presented at 6 weeks. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection1.95
Wrist Splint2.30

BCTQ Symptom Severity Subscale 6 Months

Comparison of BCTQ symptom severity between treatment groups at 6 months follow-up (1-5 scale, higher score indicates more severe symptoms). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.33
Wrist Splint2.18

BCTQ Symptom Severity Subscale 6 Months (CC)

"Sensitivity analysis for comparison of BCTQ symptom severity between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more severe symptoms) on participants with complete data. BCTQ:~Boston Carpal Tunnel Questionnaire" (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.29
Wrist Splint2.16

BCTQ Symptom Severity Subscale 6 Months (PP)

"Per protocol analysis for comparison of BCTQ symptom severity between treatment groups at 6 months follow-up (scale 1-5, higher score indicates more severe symptoms) on participants with complete data. BCTQ:~Boston Carpal Tunnel Questionnaire" (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection2.28
Wrist Splint2.15

BCTQ Symptom Severity Subscale 6 Weeks

Comparison of BCTQ symptom severity between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.12
Wrist Splint2.43

BCTQ Symptom Severity Subscale 6 Weeks (CC)

"Sensitivity analysis for comparison of BCTQ symptom severity between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms) on participants with complete data. BCTQ:~Boston Carpal Tunnel Questionnaire" (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.07
Wrist Splint2.44

BCTQ Symptom Severity Subscale 6 Weeks (PP)

"Per protocol analysis for comparison of BCTQ symptom severity between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms) on participants with complete data. BCTQ:~Boston Carpal Tunnel Questionnaire" (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.07
Wrist Splint2.44

Hand-wrist Pain Intensity 6 Months

Comparison of pain scores between treatment groups at 6 months follow-up. 0-10 scale, higher score indicates more pain. (NCT02038452)
Timeframe: 6 months

Interventionunits on a scale (Mean)
Steroid Injection4.32
Wrist Splint3.46

Hand-wrist Pain Intensity 6 Months (CC)

Sensitivity analysis for comparison of pain scores between treatment groups at 6 months follow-up (scale 0-10, higher score indicates more pain) on participants with complete data. (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection4.11
Wrist Splint3.29

Hand-wrist Pain Intensity 6 Months (PP)

Per protocol analysis for comparison of pain scores between treatment groups at 6 months follow-up (scale 0-10, higher score indicates more pain) on participants with complete data. (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection4.11
Wrist Splint3.38

Hand-wrist Pain Intensity 6 Weeks

Comparison of pain scores between treatment groups at 6 weeks follow-up (0-10 scale, higher score indicates more pain). (NCT02038452)
Timeframe: 6 weeks

Interventionunits on a scale (Mean)
Steroid Injection3.42
Wrist Splint4.28

Hand-wrist Pain Intensity 6 Weeks (CC)

Sensitivity analysis for comparison of pain scores between treatment groups at 6 weeks follow-up (scale 0-10, higher score indicates more pain) on participants with complete data. (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection3.33
Wrist Splint4.28

Hand-wrist Pain Intensity 6 Weeks (PP)

Per protocol analysis for comparison of pain scores between treatment groups at 6 weeks follow-up (higher score indicates more pain) on participants with complete data. (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection3.33
Wrist Splint4.44

Hand-wrist Pain Intensity Over 24 Months: 12 Months

Comparison of pain scores between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 0-10, higher score indicates more pain. Results are presented at 12 months. (NCT02038452)
Timeframe: 12 months

Interventionscore on a scale (Mean)
Steroid Injection3.17
Wrist Splint3.14

Hand-wrist Pain Intensity Over 24 Months: 24 Months

Comparison of pain scores between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 0-10, higher score indicates more pain. Results are presented at 24 months. (NCT02038452)
Timeframe: 24 months

Interventionscore on a scale (Mean)
Steroid Injection2.81
Wrist Splint2.40

Hand-wrist Pain Intensity Over 24 Months: 6 Months

Comparison of pain scores between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 0-10, higher score indicates more pain. Results are presented at 6 months. (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection4.11
Wrist Splint3.29

Hand-wrist Pain Intensity Over 24 Months: 6 Weeks

Comparison of pain scores between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 0-10, higher score indicates more pain. Results are presented at 6 weeks. (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection3.33
Wrist Splint4.28

NHS Cost Differences at 12 Months

Cost of interventions at 12 months (NCT02038452)
Timeframe: 12 months

InterventionUK Pounds (Mean)
Steroid Injection508.69
Wrist Splint395.54

NHS Cost Differences at 24 Months

Cost of interventions at 24 months (NCT02038452)
Timeframe: 24 months

InterventionUK Pounds (Mean)
Steroid Injection657.87
Wrist Splint586.77

NHS Cost Differences at 6 Months

Cost of interventions at 6 months (NCT02038452)
Timeframe: 6 months

InterventionUK Pounds (Mean)
Steroid Injection346.78
Wrist Splint313.24

NHS Cost Differences at 6 Months (CC)

Complete case analysis on the cost of interventions at 6 months (NCT02038452)
Timeframe: 6 months

InterventionUK Pounds (Mean)
Steroid Injection353.48
Wrist Splint306.42

QALYS at 12 Months (Cross-walk Tariff)

"The Quality Adjusted Life Years (QALYs) is a measure of the state of health of a person/group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. One QALY is equal to 1 year of life in perfect health. QALYs are calculated by estimating the years of life remaining for a patient following a particular treatment/intervention and weighting each year with a quality-of-life score (on a 0 to 1 scale). It is often measured in terms of the person's ability to carry out the activities of daily life and freedom from pain and mental disturbance. The QALY does not have a maximum score.~Cross-walk tariff: Crosswalk value sets were developed from a study of respondents who completed both the EQ-5D-3L and EQ-5D-5L. The crosswalk used a non-parametric response mapping method to predict values that are linked to the EQ-5D-3L value set. In short, the cross-walk tariff maps EQ-5D-5L values." (NCT02038452)
Timeframe: 12 months

Interventionscore on a scale (Mean)
Steroid Injection0.723
Wrist Splint0.736

QALYS at 24 Months (Cross-walk Tariff)

"The Quality Adjusted Life Years (QALYs) is a measure of the state of health of a person/group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. One QALY is equal to 1 year of life in perfect health. QALYs are calculated by estimating the years of life remaining for a patient following a particular treatment/intervention and weighting each year with a quality-of-life score (on a 0 to 1 scale). It is often measured in terms of the person's ability to carry out the activities of daily life and freedom from pain and mental disturbance. The QALY does not have a maximum score.~Cross-walk tariff: Crosswalk value sets were developed from a study of respondents who completed both the EQ-5D-3L and EQ-5D-5L. The crosswalk used a non-parametric response mapping method to predict values that are linked to the EQ-5D-3L value set. In short, the cross-walk tariff maps EQ-5D-5L values." (NCT02038452)
Timeframe: 24 months

Interventionscore on a scale (Mean)
Steroid Injection1.461
Wrist Splint1.497

QALYS at 6 Months (Cross-walk Tariff)

"The Quality Adjusted Life Years (QALYs) is a measure of the state of health of a person/group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. One QALY is equal to 1 year of life in perfect health. QALYs are calculated by estimating the years of life remaining for a patient following a particular treatment/intervention and weighting each year with a quality-of-life score (on a 0 to 1 scale). It is often measured in terms of the person's ability to carry out the activities of daily life and freedom from pain and mental disturbance. The QALY does not have a maximum score.~Cross-walk tariff: Crosswalk value sets were developed from a study of respondents who completed both the EQ-5D-3L and EQ-5D-5L. The crosswalk used a non-parametric response mapping method to predict values that are linked to the EQ-5D-3L value set. In short, the cross-walk tariff maps EQ-5D-5L values." (NCT02038452)
Timeframe: 6 months

Interventionscore on a scale (Mean)
Steroid Injection0.354
Wrist Splint0.356

Secondary: BCTQ Symptom Severity and Functional Limitations Over 24 Months: 24 Months

Comparison of overall BCTQ between treatment groups across all time points (6 weeks, 6-, 12-, and 24 month follow-up). Scale 1-5, higher score indicates more severe symptoms and functional impairment. Results are presented at 24 months. BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 24 months

Interventionscore on a scale (Mean)
Steroid Injection1.79
Wrist Splint1.73

Symptom Severity and Limitations in Hand Function as Assessed by the BCTQ 6 Weeks

Comparison of overall BCTQ between treatment groups at 6 weeks follow-up (scale 1-5, higher score indicates more severe symptoms and functional impairment). BCTQ: Boston Carpal Tunnel Questionnaire (NCT02038452)
Timeframe: 6 weeks

Interventionscore on a scale (Mean)
Steroid Injection2.02
Wrist Splint2.29

Trials

9 trials available for methylprednisolone acetate and Carpal Tunnel Syndrome

ArticleYear
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 10-20, Volume: 392, Issue:10156

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Female; Humans

2018
Ultrasound-guided insulin injection for carpal tunnel syndrome in type 2 diabetes mellitus patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Carpal Tunnel Syndrome; Diabetes Mellitus, Type 2; Electrophysiology; Femal

2019
Ultrasound-guided insulin injection for carpal tunnel syndrome in type 2 diabetes mellitus patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Carpal Tunnel Syndrome; Diabetes Mellitus, Type 2; Electrophysiology; Femal

2019
Ultrasound-guided insulin injection for carpal tunnel syndrome in type 2 diabetes mellitus patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Carpal Tunnel Syndrome; Diabetes Mellitus, Type 2; Electrophysiology; Femal

2019
Ultrasound-guided insulin injection for carpal tunnel syndrome in type 2 diabetes mellitus patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Carpal Tunnel Syndrome; Diabetes Mellitus, Type 2; Electrophysiology; Femal

2019
The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome: the INSTINCTS randomised clinical trial study protocol.
    BMC musculoskeletal disorders, 2016, 10-06, Volume: 17, Issue:1

    Topics: Adult; Carpal Tunnel Syndrome; Cost-Benefit Analysis; Glucocorticoids; Hand; Humans; Injections; Met

2016
Repeated electrophysiologic studies in patients with carpal tunnel syndrome following local corticosteroid injection using a novel approach.
    The Israel Medical Association journal : IMAJ, 2011, Volume: 13, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Electromyography; Female; Follow-Up S

2011
Long-term outcome of carpal tunnel syndrome after conservative treatment.
    International journal of clinical practice, 2004, Volume: 58, Issue:4

    Topics: Administration, Oral; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Humans; Injections; Methylpr

2004
A prospective study of the long-term efficacy of local methyl prednisolone acetate injection in the management of mild carpal tunnel syndrome.
    Rheumatology (Oxford, England), 2005, Volume: 44, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Electromyography; Female; Follow-Up S

2005
Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial.
    International journal of clinical practice, 2005, Volume: 59, Issue:12

    Topics: Analgesia; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Double-Blind Method; Female; Humans; In

2005
Lidocaine patch 5 for carpal tunnel syndrome: how it compares with injections: a pilot study.
    The Journal of family practice, 2006, Volume: 55, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Anti-I

2006
Corticosteroid injection vs. nonsteroidal antiinflammatory drug and splinting in carpal tunnel syndrome.
    American journal of physical medicine & rehabilitation, 2002, Volume: 81, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carpal Tunnel Syndrome; El

2002

Other Studies

3 other studies available for methylprednisolone acetate and Carpal Tunnel Syndrome

ArticleYear
Median nerve injury after carpal tunnel injection serially followed by ultrasonographic, sonoelastographic, and electrodiagnostic studies.
    American journal of physical medicine & rehabilitation, 2011, Volume: 90, Issue:4

    Topics: Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Female; Humans; Injections, Intra-Articular; Media

2011
Nerve injury following steroid injection for carpal tunnel syndrome. A report of two cases.
    Journal of hand surgery (Edinburgh, Scotland), 1996, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Female; Humans; Male; Median Nerve; Methylpredniso

1996
Carpal tunnel syndrome in amyotrophic lateral sclerosis and late onset cerebellar ataxia.
    Journal of hand surgery (Edinburgh, Scotland), 1996, Volume: 21, Issue:4

    Topics: Aged; Amyotrophic Lateral Sclerosis; Anti-Inflammatory Agents; Carpal Tunnel Syndrome; Cerebellar At

1996