methylprednisolone acetate has been researched along with Arthritis, Degenerative in 21 studies
Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To (1) demonstrate whether a controlled p-ACL injury model (anteromedial band transection) develops progressive gross morphological and histological posttraumatic osteoarthritis (PTOA)-like changes at 20 and 40 weeks after the injury and (2) investigate the efficacy of repeated (0, 5, 10, and 15 weeks) intra-articular injections of methylprednisolone acetate (MPA; 80 mg/mL) in the mitigation of potential PTOA-like changes after p-ACL transection." | 7.88 | Posttraumatic Osteoarthritis Development and Progression in an Ovine Model of Partial Anterior Cruciate Ligament Transection and Effect of Repeated Intra-articular Methylprednisolone Acetate Injections on Early Disease. ( Achari, Y; Barton, KI; Chung, M; Frank, CB; Hart, DA; Heard, BJ; Martin, CR; Sevick, JL; Shekarforoush, SMM; Shrive, NG, 2018) |
| "To examine the effect of intraarticular injections of methylprednisolone acetate (MA) on osteoarthritic lesions and chondrocyte stromelysin synthesis in experimental osteoarthritis (OA)." | 7.69 | Intraarticular injections with methylprednisolone acetate reduce osteoarthritic lesions in parallel with chondrocyte stromelysin synthesis in experimental osteoarthritis. ( Gunja-Smith, Z; Martel-Pelletier, J; Mineau, F; Pelletier, JP; Raynauld, JP; Woessner, JF, 1994) |
| "Shoulder osteoarthritis affect about 32% of patients over 60 years." | 5.37 | Efficacy of Hylan G-F 20 versus 6-methylprednisolone acetate in painful shoulder osteoarthritis: a retrospective controlled trial. ( Merolla, G; Paladini, P; Porcellini, G; Sperling, JW, 2011) |
| "To (1) demonstrate whether a controlled p-ACL injury model (anteromedial band transection) develops progressive gross morphological and histological posttraumatic osteoarthritis (PTOA)-like changes at 20 and 40 weeks after the injury and (2) investigate the efficacy of repeated (0, 5, 10, and 15 weeks) intra-articular injections of methylprednisolone acetate (MPA; 80 mg/mL) in the mitigation of potential PTOA-like changes after p-ACL transection." | 3.88 | Posttraumatic Osteoarthritis Development and Progression in an Ovine Model of Partial Anterior Cruciate Ligament Transection and Effect of Repeated Intra-articular Methylprednisolone Acetate Injections on Early Disease. ( Achari, Y; Barton, KI; Chung, M; Frank, CB; Hart, DA; Heard, BJ; Martin, CR; Sevick, JL; Shekarforoush, SMM; Shrive, NG, 2018) |
| "To examine the effect of intraarticular injections of methylprednisolone acetate (MA) on osteoarthritic lesions and chondrocyte stromelysin synthesis in experimental osteoarthritis (OA)." | 3.69 | Intraarticular injections with methylprednisolone acetate reduce osteoarthritic lesions in parallel with chondrocyte stromelysin synthesis in experimental osteoarthritis. ( Gunja-Smith, Z; Martel-Pelletier, J; Mineau, F; Pelletier, JP; Raynauld, JP; Woessner, JF, 1994) |
| "Shoulder osteoarthritis affect about 32% of patients over 60 years." | 1.37 | Efficacy of Hylan G-F 20 versus 6-methylprednisolone acetate in painful shoulder osteoarthritis: a retrospective controlled trial. ( Merolla, G; Paladini, P; Porcellini, G; Sperling, JW, 2011) |
| " The highest dosage of MPA (10 mg/ml) reduced GAG synthesis less than lower dosages of MPA and all dosages of TA." | 1.32 | Effects of dosage titration of methylprednisolone acetate and triamcinolone acetonide on interleukin-1-conditioned equine articular cartilage explants in vitro. ( Baxter, GM; Dechant, JE; Frisbie, DD; McIlwraith, CW; Trotter, GW, 2003) |
| "Osteoarthrosis of the zygapophyseal joint (Z-joint) is a potential cause of chronic cervical pain." | 1.32 | [Relief of chronic cervical pain after selective blockade of zygapophyseal joint]. ( Folman, Y; Gepstein, R; Livshitz, A; Shabat, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Backhouse, MR | 1 |
| Halstead, J | 1 |
| Roddy, E | 1 |
| Dhukaram, V | 1 |
| Chapman, A | 1 |
| Arnold, S | 1 |
| Bruce, J | 1 |
| Barton, KI | 1 |
| Heard, BJ | 1 |
| Sevick, JL | 1 |
| Martin, CR | 1 |
| Shekarforoush, SMM | 1 |
| Chung, M | 1 |
| Achari, Y | 1 |
| Frank, CB | 1 |
| Shrive, NG | 1 |
| Hart, DA | 1 |
| Trahan, RA | 1 |
| Byron, CR | 1 |
| Dahlgren, LA | 1 |
| Pleasant, RS | 1 |
| Werre, SR | 1 |
| McIlwraith, CW | 2 |
| Lattermann, C | 1 |
| Jahangiri, A | 1 |
| Moghaddam, FR | 1 |
| Najafi, S | 1 |
| Panusa, A | 1 |
| Regazzoni, L | 1 |
| Aldini, G | 1 |
| Orioli, M | 1 |
| Giombini, A | 1 |
| Minghetti, P | 1 |
| Tranquilli, C | 1 |
| Carini, M | 1 |
| Merolla, G | 1 |
| Sperling, JW | 1 |
| Paladini, P | 1 |
| Porcellini, G | 1 |
| Dechant, JE | 1 |
| Baxter, GM | 1 |
| Frisbie, DD | 1 |
| Trotter, GW | 1 |
| Day, CS | 1 |
| Gelberman, R | 1 |
| Patel, AA | 1 |
| Vogt, MT | 1 |
| Ditsios, K | 1 |
| Boyer, MI | 1 |
| Folman, Y | 1 |
| Livshitz, A | 1 |
| Shabat, S | 1 |
| Gepstein, R | 1 |
| KLEIN, R | 1 |
| Serena, A | 1 |
| Schumacher, J | 1 |
| Schramme, MC | 1 |
| Degraves, F | 1 |
| Bell, E | 1 |
| Ravis, W | 1 |
| Joshi, R | 1 |
| Stahl, S | 1 |
| Karsh-Zafrir, I | 1 |
| Ratzon, N | 1 |
| Rosenberg, N | 1 |
| Labens, R | 1 |
| Mellor, DJ | 1 |
| Voûte, LC | 1 |
| Pelletier, JP | 1 |
| Mineau, F | 1 |
| Raynauld, JP | 1 |
| Woessner, JF | 1 |
| Gunja-Smith, Z | 1 |
| Martel-Pelletier, J | 1 |
| Bonner, W | 1 |
| Young, L | 1 |
| Katrib, A | 1 |
| Cuello, C | 1 |
| Vollmer-Conna, U | 1 |
| Bertouch, JV | 1 |
| Roberts-Thomson, PJ | 1 |
| Ahern, MJ | 1 |
| Smith, MD | 1 |
| Youssef, PP | 1 |
| Pasquali Ronchetti, I | 1 |
| Guerra, D | 1 |
| Taparelli, F | 1 |
| Boraldi, F | 1 |
| Bergamini, G | 1 |
| Mori, G | 1 |
| Zizzi, F | 1 |
| Frizziero, L | 1 |
| Reeves, PT | 1 |
| Hanrahan, P | 1 |
| Edelman, J | 1 |
| Ilett, KF | 1 |
| Borisiuk, BE | 1 |
| Perepel'chenko, AI | 1 |
| Petrusenko, NE | 1 |
| Bulakh, EP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Which is More Effective: Prolotherapy or Paraffin Waxes for Hand Ostearthritis[NCT03839108] | 42 participants (Actual) | Interventional | 2018-12-14 | Completed | |||
| A Randomized Trial of Cortisone Injection Versus Bone Marrow Aspirate Injection Therapy for Glenohumeral Osteoarthritis[NCT03580148] | Phase 2/Phase 3 | 34 participants (Actual) | Interventional | 2015-10-08 | Completed | ||
| Multicenter Prospective Study on Basal Joint Arthritis of the Thumb[NCT01376024] | 500 participants (Anticipated) | Observational | 2007-03-31 | Recruiting | |||
| Randomized, Double Blind Comparison Trial of Prolotherapy (Dextrose) Compared to Corticosteroid Injection for the Treatment of Symptomatic Thumb Carpo-metacarpal Joint Arthritis[NCT00685880] | 2 participants (Actual) | Interventional | 2008-05-31 | Terminated (stopped due to Unable to recruit adequate numbers of patients) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for methylprednisolone acetate and Arthritis, Degenerative
| Article | Year |
|---|---|
Hypertonic dextrose versus corticosteroid local injection for the treatment of osteoarthritis in the first carpometacarpal joint: a double-blind randomized clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Carpometacarpal Joints | 2014 |
Basal joint osteoarthritis of the thumb: a prospective trial of steroid injection and splinting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Male; Methylprednisolone; | 2004 |
Basal joint osteoarthritis of the thumb: a prospective trial of steroid injection and splinting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Male; Methylprednisolone; | 2004 |
Basal joint osteoarthritis of the thumb: a prospective trial of steroid injection and splinting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Male; Methylprednisolone; | 2004 |
Basal joint osteoarthritis of the thumb: a prospective trial of steroid injection and splinting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Male; Methylprednisolone; | 2004 |
Intraarticular corticosteroid injection for first carpometacarpal osteoarthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Injections, Intra-Articular; Male | 2005 |
Intraarticular corticosteroid injection for first carpometacarpal osteoarthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Injections, Intra-Articular; Male | 2005 |
Intraarticular corticosteroid injection for first carpometacarpal osteoarthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Injections, Intra-Articular; Male | 2005 |
Intraarticular corticosteroid injection for first carpometacarpal osteoarthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Female; Humans; Injections, Intra-Articular; Male | 2005 |
Comparison of intraarticular injection of depot corticosteroid and hyaluronic acid for treatment of degenerative trapeziometacarpal joints.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Carpal Joints; Del | 2005 |
Effects of intraarticular glucocorticoids on macrophage infiltration and mediators of joint damage in osteoarthritis synovial membranes: findings in a double-blind, placebo-controlled study.
Topics: Aged; Cell Movement; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Double-Blind Method; Female; Gl | 2001 |
Morphological analysis of knee synovial membrane biopsies from a randomized controlled clinical study comparing the effects of sodium hyaluronate (Hyalgan) and methylprednisolone acetate (Depomedrol) in osteoarthritis.
Topics: Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents; Biopsy; Female; Humans; Hyaluronic Acid; In | 2001 |
15 other studies available for methylprednisolone acetate and Arthritis, Degenerative
| Article | Year |
|---|---|
A multi-professional survey of UK practice in the use of intra-articular corticosteroid injection for symptomatic first metatarsophalangeal joint osteoarthritis.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Cross-Sectional Studies; Humans; Injections, Intra-Arti | 2023 |
Posttraumatic Osteoarthritis Development and Progression in an Ovine Model of Partial Anterior Cruciate Ligament Transection and Effect of Repeated Intra-articular Methylprednisolone Acetate Injections on Early Disease.
Topics: Animals; Anterior Cruciate Ligament Injuries; Cartilage, Articular; Disease Progression; Female; Inj | 2018 |
In vitro effects of three equimolar concentrations of methylprednisolone acetate, triamcinolone acetonide, and isoflupredone acetate on equine articular tissue cocultures in an inflammatory environment.
Topics: Animals; Cartilage, Articular; Coculture Techniques; Dinoprostone; Female; Fluprednisolone; Glycosam | 2018 |
Intra-articular Corticosteroids for Knee Pain-What Have We Learned from the Equine Athlete and Current Best Practice.
Topics: Animals; Arthralgia; Betamethasone; Cartilage, Articular; Drug Therapy, Combination; Glucocorticoids | 2019 |
Urinary profile of methylprednisolone acetate metabolites in patients following intra-articular and intramuscular administration.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Injections, Intra-Articular; Injections, Intram | 2011 |
Efficacy of Hylan G-F 20 versus 6-methylprednisolone acetate in painful shoulder osteoarthritis: a retrospective controlled trial.
Topics: Aged; Anti-Inflammatory Agents; Biocompatible Materials; Female; Humans; Hyaluronic Acid; Injections | 2011 |
Effects of dosage titration of methylprednisolone acetate and triamcinolone acetonide on interleukin-1-conditioned equine articular cartilage explants in vitro.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Culture Techniques; DNA; Dose-Response Rela | 2003 |
[Relief of chronic cervical pain after selective blockade of zygapophyseal joint].
Topics: Anti-Inflammatory Agents; Female; Humans; Injections, Intra-Articular; Male; Methylprednisolone; Met | 2004 |
PARENTERAL METHYLPREDNISOLONE ACETATE IN THE MANAGEMENT OF ARTHROPATHIES.
Topics: Arthritis; Arthritis, Rheumatoid; Bursitis; Geriatrics; Gout; Humans; Methylprednisolone; Methylpred | 1963 |
Concentration of methylprednisolone in the centrodistal joint after administration of methylprednisolone acetate in the tarsometatarsal joint.
Topics: Animals; Anti-Inflammatory Agents; Cadaver; Chromatography, High Pressure Liquid; Horse Diseases; Ho | 2005 |
Retrospective study of the effect of intra-articular treatment of osteoarthritis of the distal tarsal joints in 51 horses.
Topics: Animals; Anti-Inflammatory Agents; Drug Therapy, Combination; Female; Horse Diseases; Horses; Hyalur | 2007 |
Intraarticular injections with methylprednisolone acetate reduce osteoarthritic lesions in parallel with chondrocyte stromelysin synthesis in experimental osteoarthritis.
Topics: Animals; Cartilage, Articular; Dogs; Immunohistochemistry; Injections, Intra-Articular; Matrix Metal | 1994 |
A help for painful osteoarthritis of the knee: "doctor, you sure know where to mash.".
Topics: Anesthetics, Local; Anti-Inflammatory Agents; Humans; Injections, Intra-Articular; Knee Joint; Methy | 1993 |
Effect of intra-articular glucocorticoids on the disposition of sulphadimidine in chronic osteoarthritis patients.
Topics: Acetylation; Aged; Chronic Disease; Female; Half-Life; Humans; Injections, Intra-Articular; Male; Me | 1988 |
[Use of depo-medrol in the complex conservative treatment of patients with arthroses deformans].
Topics: Adult; Aged; Anti-Inflammatory Agents; Combined Modality Therapy; Female; Humans; Injections, Intra- | 1985 |