Page last updated: 2024-11-07

methylprednisolone acetate and Arthralgia

methylprednisolone acetate has been researched along with Arthralgia in 4 studies

Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.
methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.

Arthralgia: Pain in the joint.

Research Excerpts

Excerpt	Relevance	Reference
" Knee pain (Numeric Rating Scale [NRS]), Oxford Knee Score, overall treatment effect (Global Perceived Effect), analgesic drug use, and adverse events were compared between CRFA and IAS cohorts at 1, 3, and 6 months after intervention."	2.87	Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. ( Buvanendran, A; Choi, D; Davis, T; DePalma, M; Desai, M; Gupta, A; Hunter, C; Kapural, L; Lindley, D; Loudermilk, E; Patel, N; Soloman, M, 2018)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, T	1
Loudermilk, E	1
DePalma, M	1
Hunter, C	1
Lindley, D	1
Patel, N	1
Choi, D	1
Soloman, M	1
Gupta, A	1
Desai, M	1
Buvanendran, A	1
Kapural, L	1
McIlwraith, CW	1
Lattermann, C	1
Wisniewski, SJ	1
Murthy, N	1
Smith, J	1
Carson, BW	1
Wong, A	1

Clinical Trials (5)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Proof-of-Concept Study to Define the Safety, Efficacy and Feasibility of Cryoanalgesia (Iovera°®) for the Treatment of Pain in Subjects With Morton's Neuroma[NCT05604144]		5 participants (Anticipated)	Interventional	2022-08-22	Active, not recruiting
Cooled Genicular Radiofrequency Ablation Versus Conventional Genicular Radiofrequency Ablation for the Treatment of Chronic Knee Pain: A Prospective Study[NCT04275128]		1 participants (Actual)	Observational	2020-07-11	Terminated (stopped due to Insurance companies no longer cover this procedure)
Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With OA of the Hip Compared to Intra-articular Steroid Injections[NCT04329884]		60 participants (Anticipated)	Interventional	2019-12-01	Recruiting
A Prospective, Multi-Center, RCT Evaluating the Safety and Effectiveness of Coolief™ Cooled Radiofrequency Probe to Create Lesions of the Genicular Nerves and Comparing Corticosteroid Injection in the Management of Knee Pain[NCT02343003]		151 participants (Actual)	Interventional	2015-01-31	Completed
Randomized, Double-blinded, Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections[NCT06000709]	Phase 4	40 participants (Anticipated)	Interventional	2023-10-20	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Numeric Rating Scale

"The number of subjects whose knee pain is reduced from baseline by ≥ 50% based on the Numeric Rating Scale (NRS) at 12 months. The NRS is an 11-point scale (0 points to 10 points), where 0 points equals no pain and 10 points equals the worst pain." (NCT02343003)
Timeframe: 12 months

Intervention	Participants (Count of Participants)
Cooled Radiofrequency	34
Corticosteroid Injection	2

Numeric Rating Scale (NRS)

"The number of subjects whose knee pain is reduced by ≥ 50% based on the Numeric Rating Scale (NRS). The NRS is an 11-point scale (0 points to 10 points), where 0 points equals no pain and 10 points equals the worst pain." (NCT02343003)
Timeframe: 6 months

Intervention	Participants (Count of Participants)
Cooled Radiofrequency	43
Corticosteroid Injection	11

Medication Usage

Reduction in pain medication usage from baseline as measured by subject self-reported average daily dosage. (NCT02343003)
Timeframe: 6 months and 12 months

Intervention	milligrams (Mean)
	6 months post-intervention	12 months post-intervention
Cooled Radiofrequency	2.4	1
Corticosteroid Injection	-0.6	2.5

Oxford Knee Score

"Improvement in global outcome from baseline as measured by the Oxford Knee Score at 6 months and 12 months. The Oxford Knee Score is determined by a 12-question survey that measures knee function, and is scored on a scale that ranges from 0 - 48 points, with scores of 0 - 19 = severe arthritis, 20 - 29 = moderate to severe arthritis, 30 - 39 = mild to moderate arthritis, and 40 - 48 = satisfactory joint function." (NCT02343003)
Timeframe: 6 months and 12 months

Intervention	units on a scale (Mean)
	6 months post-intervention	12 months post-intervention
Cooled Radiofrequency	18.5	17.3
Corticosteroid Injection	5.7	8.7

Safety: Number of Subjects Experiencing Adverse Events Through Final Follow up.

Safety Endpoint: Number of subjects experiencing adverse events through final follow up. (NCT02343003)
Timeframe: 6 months and 12 months

Intervention	Participants (Count of Participants)
	6 months post-intervention	12 months post-intervention
Cooled Radiofrequency	34	12
Corticosteroid Injection	31	3

Subject Satisfaction - Number of Participants With a Global Perceived Effect Score of 5 or Greater

"Subject satisfaction as measured by the Global Perceived Effect Score at 6 months and 12 months. The study subjects' perception of treatment effect was reflected by the Global Perceived Effect (GPE). The Global Perceived Effect is a 7-point scale: 1 point = worst ever, 2 points = much worse, 3 points = worse, 4 points = not improved but not worse, 5 points = improved, 6 points = much improved, 7 points = best ever." (NCT02343003)
Timeframe: 6 months and 12 months

Intervention	Participants (Count of Participants)
	6 months post-intervention	12 months post-intervention
Cooled Radiofrequency	53	39
Corticosteroid Injection	16	2

Trials

1 trial available for methylprednisolone acetate and Arthralgia

Article	Year
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018
Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis. Regional anesthesia and pain medicine, 2018, Volume: 43, Issue:1 Topics: Adrenal Cortex Hormones; Aged; Analgesics; Arthralgia; Betamethasone; Catheter Ablation; Combined Mo	2018

Other Studies

3 other studies available for methylprednisolone acetate and Arthralgia

Article	Year
Intra-articular Corticosteroids for Knee Pain-What Have We Learned from the Equine Athlete and Current Best Practice. The journal of knee surgery, 2019, Volume: 32, Issue:1 Topics: Animals; Arthralgia; Betamethasone; Cartilage, Articular; Drug Therapy, Combination; Glucocorticoids	2019
Ultrasound evaluation of Baker cysts: diagnosis and management. PM & R : the journal of injury, function, and rehabilitation, 2012, Volume: 4, Issue:7 Topics: Anti-Inflammatory Agents; Arthralgia; Humans; Injections, Intra-Articular; Knee Joint; Male; Methylp	2012
Ultrasonographic guidance for injections of local steroids in the native hip. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1999, Volume: 18, Issue:2 Topics: Anti-Inflammatory Agents; Arthralgia; Hip Joint; Humans; Injections, Intra-Articular; Methylpredniso	1999