Page last updated: 2024-10-31

methylphenidate and Syndrome

methylphenidate has been researched along with Syndrome in 25 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"A 28-year-old woman with a long history of drug abuse experienced flaccid quadriplegia and bilateral loss of posterior column sensation a few minutes after an intravenous (IV) injection of methylphenidate hydrochloride."3.66Medial medullary syndrome in a drug abuser. ( Gonatas, NK; Lewis, RA; Mizutani, T, 1980)
"Although the FDA recommends imipramine hydrochloride (IMI) only for temporary relief of symptoms of enuresis nocturna (EN), the drug has been applied to a number of other pediatric situations, including the Hyperkinetic Syndrome (HS), childhood depression, somnambulism and pavor nocturnus, school phobia, petit mal epilepsy, allergies, autism, encorpresis and head-banging."3.65Imipramine and children: a review and some speculations about the mechanism of drug action. ( Gualtieri, CT, 1977)
"Treatment with methylphenidate has long been considered as a first choice for disabling forms of ADHD, but recent data do not show evidence for superiority of methylphenidate compared to non pharmacological approach at long-term."1.35[Attention deficit disorder in childhood]. ( Van Bogaert, P, 2009)
"The cause of this syndrome is unknown, in some cases a relationship between infectious disease or traumatic brain damage has been postulated."1.28[The Kleine-Levin syndrome]. ( Boer, F; Njiokiktjien, C; Smit, LM; Smith, F; Visscher, F, 1989)
"A possibly different mechanism in hypersomnia and hypersexuality is speculated."1.26The Kleine-Levine syndrome--a variant? ( Nair, NP; Yassa, R, 1978)
"Deanol did not produce the anticipated elevation in choline levels postulated to be one mechanism of its action."1.26Deanol acetamidobenzoate (Deaner) in tardive dyskinesia. ( Fann, WE; Stafford, JR, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199017 (68.00)18.7374
1990's4 (16.00)18.2507
2000's3 (12.00)29.6817
2010's0 (0.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Çetin, FH1
Barış Usta, M1
Aydın, S1
Güven, AS1
Auyeung, SF1
Long, Q1
Royster, EB1
Murthy, S1
McNutt, MD1
Lawson, D1
Miller, A1
Manatunga, A1
Musselman, DL1
Van Bogaert, P1
ZAPLETALEK, M1
VOBORSKA, D1
BARBORAKOVA, E1
KOMENDA, S1
Gothelf, D1
Gruber, R1
Presburger, G1
Dotan, I1
Brand-Gothelf, A1
Burg, M1
Inbar, D1
Steinberg, T1
Frisch, A1
Apter, A1
Weizman, A1
Lenz, H1
Harbauer, H1
Mizutani, T1
Lewis, RA1
Gonatas, NK1
Rosenthal, NE1
Kirrane, R1
Bodner, R1
Lynch, T2
Bodner, RA1
Lewis, L1
Kahn, D1
Spencer, T1
Biederman, J1
Wilens, TE1
Faraone, SV1
Billiard, M1
Guilleminault, C1
Dement, WC1
Chiles, JA1
Wilkus, RJ1
Yassa, R1
Nair, NP1
Oettinger, L1
Gualtieri, CT1
Weiss, G1
Hechtman, L1
Stafford, JR1
Fann, WE1
Wolf, J1
Fein, A1
Fehrenbacher, L1
Rie, HE1
Visscher, F1
Smit, LM1
Smith, F1
Boer, F1
Njiokiktjien, C1
Sarma, PS1
Falk, MA1
Reece, RM1

Reviews

2 reviews available for methylphenidate and Syndrome

ArticleYear
Adults with attention-deficit/hyperactivity disorder: a controversial diagnosis.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 7

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents; Atomoxetine Hydrochloride; Attention Deficit

1998
Pediatric psychopharmacology. A review with special reference to deanol.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Adolescent; Adult; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Attention Deficit Disord

1977

Trials

1 trial available for methylphenidate and Syndrome

ArticleYear
Methylphenidate treatment for attention-deficit/hyperactivity disorder in children and adolescents with velocardiofacial syndrome: an open-label study.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2003

Other Studies

22 other studies available for methylphenidate and Syndrome

ArticleYear
A Case Study on EEG Analysis: Embedding Entropy Estimations Indicate the Decreased Neuro-Cortical Complexity Levels Mediated by Methylphenidate Treatment in Children with ADHD.
    Clinical EEG and neuroscience, 2022, Volume: 53, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Electroence

2022
Sequential multiple-assignment randomized trial design of neurobehavioral treatment for patients with metastatic malignant melanoma undergoing high-dose interferon-alpha therapy.
    Clinical trials (London, England), 2009, Volume: 6, Issue:5

    Topics: Behavioral Symptoms; Citalopram; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Doubl

2009
[Attention deficit disorder in childhood].
    Revue medicale de Bruxelles, 2009, Volume: 30, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Huma

2009
[Clinical & psychotechnical study of a new medication for the neuroleptic syndrome].
    Annales medico-psychologiques, 1958, Volume: 116, Issue:4

    Topics: Antipsychotic Agents; Autonomic Agents; Humans; Methylphenidate; Nervous System Diseases; Syndrome

1958
[EFFECT OF PHENMETRAZINE AND RITALIN ON THE NEUROTIC FATIGUE SYNDROME].
    Activitas nervosa superior, 1963, Volume: 5

    Topics: Fatigue; Humans; Methylphenidate; Neurotic Disorders; Phenmetrazine; Syndrome

1963
[Kleine-Levin-syndrome (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1980, Jun-15, Volume: 130, Issue:11

    Topics: Adolescent; Body Water; Disorders of Excessive Somnolence; Feeding and Eating Disorders; Female; Hum

1980
[Hypermotoric syndrome in childhood].
    Deutsche medizinische Wochenschrift (1946), 1980, Mar-14, Volume: 105, Issue:11

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Environment; Female; Humans; Hyperkinesis; Mal

1980
Medial medullary syndrome in a drug abuser.
    Archives of neurology, 1980, Volume: 37, Issue:7

    Topics: Adult; Brain; Cerebral Infarction; Female; Humans; Injections, Intravenous; Intracranial Embolism an

1980
Syndrome triad in children and adolescents.
    The American journal of psychiatry, 1995, Volume: 152, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Circadian Rhythm; Comorbidity; Female; Humans;

1995
Response to "Sertraline and isocarboxazid cause a serotonin syndrome".
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: 1-Naphthylamine; Adult; Dextromethorphan; Drug Therapy, Combination; Female; Humans; Isocarboxazid;

1995
Serotonin syndrome.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Depressive Disorder; Humans; Isocarboxazid; Male; Methylphenidate; Middle Aged; Nervous System Disea

1995
A menstruation-linked periodic hypersomnia. Kleine-Levin syndrome or new clinical entity?
    Neurology, 1975, Volume: 25, Issue:5

    Topics: Adolescent; Disorders of Excessive Somnolence; Electroencephalography; Estrogens, Conjugated (USP);

1975
Behavioral manifestations of the Kleine-Levin syndrome.
    Diseases of the nervous system, 1976, Volume: 37, Issue:11

    Topics: Adolescent; Behavior; Disorders of Excessive Somnolence; Electroencephalography; Humans; Male; Menta

1976
The Kleine-Levine syndrome--a variant?
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:3

    Topics: Adult; Disorders of Excessive Somnolence; Feeding and Eating Disorders; Humans; Hypothalamus; Male;

1978
Imipramine and children: a review and some speculations about the mechanism of drug action.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Depression; Dopamine; Enuresis; Epilepsy, Absence;

1977
The hyperactive child syndrome.
    Science (New York, N.Y.), 1979, Sep-28, Volume: 205, Issue:4413

    Topics: Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child,

1979
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Choline; Cyproheptadine; Deanol; Drug Evaluation; Dyskinesia, Drug-Induced; Ethanolamines; Humans; M

1977
Eosinophilic syndrome with methylphenidate abuse.
    Annals of internal medicine, 1978, Volume: 89, Issue:2

    Topics: Adult; Eosinophilia; Female; Humans; Male; Methylphenidate; Middle Aged; Substance-Related Disorders

1978
Hyperactivity in children.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Child Reactive Disorders; Dextroamphetamine; D

1975
[The Kleine-Levin syndrome].
    Tijdschrift voor kindergeneeskunde, 1989, Volume: 57, Issue:6

    Topics: Adolescent; Child; Disorders of Excessive Somnolence; Humans; Hyperphagia; Male; Methylphenidate; Sl

1989
Drug treatment of hyperactivity in children.
    IMJ. Illinois medical journal, 1973, Volume: 144, Issue:2

    Topics: Age Factors; Child; Dextroamphetamine; Electroencephalography; Humans; Hyperkinesis; Imipramine; Met

1973
The hyperactive child syndrome.
    American family physician, 1973, Volume: 8, Issue:3

    Topics: Age Factors; Amphetamine; Attention Deficit Disorder with Hyperactivity; Child Behavior Disorders; C

1973