methylphenidate has been researched along with Stroke in 18 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Noninvasive transcranial direct current stimulation (tDCS) and methylphenidate (MP) are associated with motor recovery after stroke." | 9.19 | Combination of transcranial direct current stimulation and methylphenidate in subacute stroke. ( Black-Schaffer, R; Cui, H; Fregni, F; Han, SJ; Herman, S; Latif, LA; Lee, YT; Volz, MS; Wang, QM; Zafonte, R, 2014) |
| "We hypothesized that a single dose of methylphenidate (MP) would modulate cerebral motor activation and behavior in patients having suffered a subcortical stroke." | 9.12 | Methylphenidate modulates cerebral post-stroke reorganization. ( Albucher, JF; Chollet, F; Cognard, C; Conchou, F; Dechaumont-Palacin, S; Franceries, X; Gerdelat, A; Guiraud, V; Leger, A; Loubinoux, I; Marque, P; Pariente, J; Rascol, O; Tardy, J, 2006) |
| " Future studies should address the issue of the optimal therapeutic window and dosage of medications to identify those patients who would benefit most." | 6.76 | Effect of methylphenidate and/or levodopa coupled with physiotherapy on functional and motor recovery after stroke--a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman Roghani, R, 2011) |
| " We sought to prospectively study the effects of levodopa (LD) and/or methylphenidate (MPH) in combination with physiotherapy on mood and cognition following stroke in human subjects." | 6.76 | Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman-Roghani, R, 2011) |
| "Noninvasive transcranial direct current stimulation (tDCS) and methylphenidate (MP) are associated with motor recovery after stroke." | 5.19 | Combination of transcranial direct current stimulation and methylphenidate in subacute stroke. ( Black-Schaffer, R; Cui, H; Fregni, F; Han, SJ; Herman, S; Latif, LA; Lee, YT; Volz, MS; Wang, QM; Zafonte, R, 2014) |
| "We hypothesized that a single dose of methylphenidate (MP) would modulate cerebral motor activation and behavior in patients having suffered a subcortical stroke." | 5.12 | Methylphenidate modulates cerebral post-stroke reorganization. ( Albucher, JF; Chollet, F; Cognard, C; Conchou, F; Dechaumont-Palacin, S; Franceries, X; Gerdelat, A; Guiraud, V; Leger, A; Loubinoux, I; Marque, P; Pariente, J; Rascol, O; Tardy, J, 2006) |
| "Small studies performed in chronic stroke patients have indicated that single doses of reboxetine or citalopram improved different aspects of motor functions and that long-lasting application of donepezil reduced aphasic symptoms." | 4.84 | Pharmacotherapy in restorative neurology. ( Liepert, J, 2008) |
| " Future studies should address the issue of the optimal therapeutic window and dosage of medications to identify those patients who would benefit most." | 2.76 | Effect of methylphenidate and/or levodopa coupled with physiotherapy on functional and motor recovery after stroke--a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman Roghani, R, 2011) |
| " We sought to prospectively study the effects of levodopa (LD) and/or methylphenidate (MPH) in combination with physiotherapy on mood and cognition following stroke in human subjects." | 2.76 | Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman-Roghani, R, 2011) |
| "Treatment with methylphenidate has been advocated in patients with traumatic brain injury and stroke, cancer patients, and those with human immunodeficiency virus infection." | 2.41 | Methylphenidate: its pharmacology and uses. ( Challman, TD; Lipsky, JJ, 2000) |
| "Methylphenidate is an important element of therapeutic strategies for ADHD." | 1.40 | [Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate]. ( Acquaviva, E; Bange, F; Delorme, R; Le Heuzey, MF; Mouren, MC, 2014) |
| " Dosage was inversely associated with risk." | 1.38 | Methylphenidate and risk of serious cardiovascular events in adults. ( Bilker, WB; Cziraky, MJ; Daniel, GW; Guevara, JP; Hennessy, S; Kimmel, SE; Newcomb, C; Schelleman, H; Strom, BL, 2012) |
| "Stroke is a well-documented complication of amphetamine abuse." | 1.31 | Cerebral arteritis following methylphenidate use. ( Garbugino, S; Intruvini, S; Lazarowski, A; Massaro, M; Plaghos, LL; Riveros, D; Schteinschnaider, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 10 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luauté, J | 1 |
| Villeneuve, L | 1 |
| Roux, A | 1 |
| Nash, S | 1 |
| Bar, JY | 1 |
| Chabanat, E | 1 |
| Cotton, F | 1 |
| Ciancia, S | 1 |
| Sancho, PO | 1 |
| Hovantruc, P | 1 |
| Quelard, F | 1 |
| Sarraf, T | 1 |
| Cojan, Y | 1 |
| Hadj-Bouziane, F | 1 |
| Farné, A | 1 |
| Janoly-Dumenil, A | 1 |
| Boisson, D | 1 |
| Jacquin-Courtois, S | 1 |
| Rode, G | 1 |
| Rossetti, Y | 1 |
| Bange, F | 1 |
| Le Heuzey, MF | 1 |
| Acquaviva, E | 1 |
| Delorme, R | 1 |
| Mouren, MC | 1 |
| Wang, QM | 1 |
| Cui, H | 1 |
| Han, SJ | 1 |
| Black-Schaffer, R | 1 |
| Volz, MS | 1 |
| Lee, YT | 1 |
| Herman, S | 1 |
| Latif, LA | 1 |
| Zafonte, R | 1 |
| Fregni, F | 1 |
| Kim, JY | 1 |
| Baik, JS | 1 |
| Liepert, J | 1 |
| Spiegel, DR | 1 |
| Kim, J | 1 |
| Greene, K | 1 |
| Conner, C | 1 |
| Zamfir, D | 1 |
| Lokk, J | 2 |
| Salman Roghani, R | 1 |
| Delbari, A | 2 |
| Salman-Roghani, R | 1 |
| De Benedictis, L | 1 |
| Dumais, A | 1 |
| Landry, P | 1 |
| Kratochvil, CJ | 1 |
| Schelleman, H | 1 |
| Bilker, WB | 1 |
| Kimmel, SE | 1 |
| Daniel, GW | 1 |
| Newcomb, C | 1 |
| Guevara, JP | 1 |
| Cziraky, MJ | 1 |
| Strom, BL | 1 |
| Hennessy, S | 1 |
| Goldstein, LB | 1 |
| Tardy, J | 1 |
| Pariente, J | 1 |
| Leger, A | 1 |
| Dechaumont-Palacin, S | 1 |
| Gerdelat, A | 1 |
| Guiraud, V | 1 |
| Conchou, F | 1 |
| Albucher, JF | 1 |
| Marque, P | 1 |
| Franceries, X | 1 |
| Cognard, C | 1 |
| Rascol, O | 1 |
| Chollet, F | 1 |
| Loubinoux, I | 1 |
| Barrett, AM | 1 |
| Levy, CE | 1 |
| Gonzalez Rothi, LJ | 1 |
| Schteinschnaider, A | 1 |
| Plaghos, LL | 1 |
| Garbugino, S | 1 |
| Riveros, D | 1 |
| Lazarowski, A | 1 |
| Intruvini, S | 1 |
| Massaro, M | 1 |
| Challman, TD | 1 |
| Lipsky, JJ | 1 |
| Diamond, PT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment: Double Blinded Comparison Between Botulinum Toxin and Baclofen.[NCT02462317] | Phase 4 | 184 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Methylphenidate Effect on Performing Humphrey Visual Fields[NCT02162381] | 32 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| A Parallel-group, Double-blind, Placebo-controlled Study of Methylphenidate as an Add on Therapy for Mirtazapine in the Treatment of Major Depressive Disorder in Cancer Patients Under Palliative Care[NCT01497548] | Phase 3 | 120 participants (Anticipated) | Interventional | 2011-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for methylphenidate and Stroke
| Article | Year |
|---|---|
Pharmacotherapy in restorative neurology.
Topics: Brain Injuries; Donepezil; Dopamine Uptake Inhibitors; Humans; Indans; Methylphenidate; Movement; No | 2008 |
Amphetamines and related drugs in motor recovery after stroke.
Topics: Central Nervous System Stimulants; Dextroamphetamine; Humans; Methylphenidate; Motor Cortex; Movemen | 2003 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Rehabilitative management of post-stroke visuospatial inattention.
Topics: Aged; Animals; Bromocriptine; Central Nervous System Stimulants; Controlled Clinical Trials as Topic | 2001 |
5 trials available for methylphenidate and Stroke
| Article | Year |
|---|---|
Adding methylphenidate to prism-adaptation improves outcome in neglect patients. A randomized clinical trial.
Topics: Activities of Daily Living; Adaptation, Physiological; Double-Blind Method; Humans; Methylphenidate; | 2018 |
Combination of transcranial direct current stimulation and methylphenidate in subacute stroke.
Topics: Adult; Aged; Brain; Central Nervous System Stimulants; Combined Modality Therapy; Female; Hand; Huma | 2014 |
Effect of methylphenidate and/or levodopa coupled with physiotherapy on functional and motor recovery after stroke--a randomized, double-blind, placebo-controlled trial.
Topics: Activities of Daily Living; Aged; Central Nervous System Stimulants; Combined Modality Therapy; Dopa | 2011 |
Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Central Nervous System Stimulants; Cognition Disor | 2011 |
Methylphenidate modulates cerebral post-stroke reorganization.
Topics: Aged; Aging; Attention; Behavior; Brain; Central Nervous System Stimulants; Cross-Over Studies; Doub | 2006 |
9 other studies available for methylphenidate and Stroke
| Article | Year |
|---|---|
[Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate].
Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; Ch | 2014 |
Adult onset methylphenidate induced dyskinesia after stroke.
Topics: Central Nervous System Stimulants; Dyskinesia, Drug-Induced; Female; Humans; Male; Methylphenidate; | 2014 |
Apathy due to cerebrovascular accidents successfully treated with methylphenidate: a case series.
Topics: Aged; Depression; Humans; Male; Methylphenidate; Middle Aged; Mood Disorders; Motivation; Stroke; Tr | 2009 |
Successful treatment of severe disruptive disorder featuring symptoms of the Klüver-Bucy Syndrome following a massive right temporal-parietal hemorrhage.
Topics: Adrenergic alpha-Agonists; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Di | 2013 |
ADHD pharmacotherapy: rates of stimulant use and cardiovascular risk.
Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; De | 2012 |
Methylphenidate and risk of serious cardiovascular events in adults.
Topics: Adult; Aged; Central Nervous System Stimulants; Cohort Studies; Databases, Factual; Death, Sudden, C | 2012 |
Encouraging news about ADHD drugs and heart risk in adults.
Topics: Adult; Attention; Attention Deficit Disorder with Hyperactivity; Cardiovascular Diseases; Central Ne | 2012 |
Pharmaceuticals for poststroke and brain injury rehabilitation.
Topics: Amantadine; Aphasia, Broca; Brain Injuries; Dopamine Agents; Humans; Methylphenidate; Persistent Veg | 2007 |
Cerebral arteritis following methylphenidate use.
Topics: Arteritis; Central Nervous System Stimulants; Cerebral Angiography; Cerebral Arterial Diseases; Chil | 2000 |