methylphenidate has been researched along with Sleep Apnea Syndromes in 8 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with sleep apnea, brainstem functional activity is low in the awake state but becomes critically reduced during sleep, culminating in apnea-stimulated arousal followed by repetitive cycles as sleep recurs." | 1.26 | Sleep apnea, narcolepsy, and dreaming: regional cerebral hemodynamics. ( Derman, S; Karacan, I; Meyer, JS; Sakai, F; Yamamoto, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Padala, PR | 1 |
| Dennis, RA | 1 |
| Padala, KP | 1 |
| Kolla, BP | 1 |
| Mansukhani, MP | 1 |
| Golan, N | 2 |
| Shahar, E | 1 |
| Ravid, S | 1 |
| Pillar, G | 2 |
| Huang, YS | 1 |
| Guilleminault, C | 1 |
| Li, HY | 1 |
| Yang, CM | 1 |
| Wu, YY | 1 |
| Chen, NH | 1 |
| Corkum, P | 1 |
| Panton, R | 1 |
| Ironside, S | 1 |
| Macpherson, M | 1 |
| Williams, T | 1 |
| Meyer, JS | 1 |
| Sakai, F | 1 |
| Karacan, I | 1 |
| Derman, S | 1 |
| Yamamoto, M | 1 |
| van der Meché, FG | 1 |
| Bogaard, JM | 1 |
| van der Sluys, JC | 1 |
| Schimsheimer, RJ | 1 |
| Ververs, CC | 1 |
| Busch, HF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Validation of Sleep Questionnaires in the Down Syndrome Population[NCT03771469] | 81 participants (Actual) | Interventional | 2018-06-25 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methylphenidate and Sleep Apnea Syndromes
| Article | Year |
|---|---|
[The relationship between attention deficit hyperactivity disorder and sleep-alertness problems].
Topics: Adrenergic Uptake Inhibitors; Attention Deficit Disorder with Hyperactivity; Child; Dopamine Agents; | 2004 |
1 trial available for methylphenidate and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Acute impact of immediate release methylphenidate administered three times a day on sleep in children with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Biological Availability; Brain; Central Nervous Syste | 2008 |
6 other studies available for methylphenidate and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani.
Topics: Alzheimer Disease; Apathy; Double-Blind Method; Humans; Independent Living; Methylphenidate; Sleep A | 2018 |
Methylphenidate and Apathy in Alzheimer's Disease: Is Sleep Apnea a Confounding Effect?
Topics: Alzheimer Disease; Apathy; Double-Blind Method; Humans; Independent Living; Methylphenidate; Sleep A | 2018 |
Sleep disorders and daytime sleepiness in children with attention-deficit/hyperactive disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Disorders o | 2004 |
Attention-deficit/hyperactivity disorder with obstructive sleep apnea: a treatment outcome study.
Topics: Adenoidectomy; Adenoids; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimu | 2007 |
Sleep apnea, narcolepsy, and dreaming: regional cerebral hemodynamics.
Topics: Adult; Brain Stem; Cerebellum; Cerebrovascular Circulation; Dreams; Humans; Methylphenidate; Middle | 1980 |
Daytime sleep in myotonic dystrophy is not caused by sleep apnoea.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methylphenidate; Middle Aged; Myotonic Dystrophy; Pol | 1994 |