Page last updated: 2024-10-31

methylphenidate and Serotonin Syndrome

methylphenidate has been researched along with Serotonin Syndrome in 2 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, YM1
Jung, YK1
Ishii, M1
Tatsuzawa, Y1
Yoshino, A1
Nomura, S1

Other Studies

2 other studies available for methylphenidate and Serotonin Syndrome

ArticleYear
Manic switch and serotonin syndrome induced by augmentation of paroxetine with methylphenidate in a patient with major depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, May-30, Volume: 34, Issue:4

    Topics: Adolescent; Bipolar Disorder; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Male; M

2010
Serotonin syndrome induced by augmentation of SSRI with methylphenidate.
    Psychiatry and clinical neurosciences, 2008, Volume: 62, Issue:2

    Topics: Central Nervous System Stimulants; Depressive Disorder, Major; Drug Interactions; Drug Therapy, Comb

2008