methylphenidate has been researched along with Schizophrenia in 77 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study estimated the risk of developing psychotic disorders by comparing children with ADHD to non-ADHD controls, and to examine whether methylphenidate (MPH) treatment influences the risks of psychotic disorders." | 7.81 | Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan. ( Lee, SY; Lee, TL; Shyu, YC; Wang, LJ; Yang, CJ; Yang, KC; Yuan, SS, 2015) |
| "Methylphenidate produced an increase in psychopathology reflected by a worsening of both positive and negative symptoms." | 5.28 | Behavioral response to methylphenidate and treatment outcome in first episode schizophrenia. ( Alvir, JM; Geisler, S; Jody, D; Lieberman, JA; Szymanski, S, 1990) |
| "Although neuroleptics are the major treatment for schizophrenia, there are no effective measures to determine the appropriate or necessary length of neuroleptic maintenance." | 5.27 | Methylphenidate challenge as a predictor of relapse in schizophrenia. ( Brenner, R; Gadaleta, D; Kane, JM; Kinon, B; Lesser, MS; Lieberman, JA, 1984) |
| "To investigate the mood response of schizophrenic subjects to psychostimulant challenge, 29 neuroleptic-treated subjects (22 with schizophrenia and 7 with schizoaffective disorder) in clinical remission received two infusions, one with methylphenidate 0." | 5.07 | Mood responses of remitted schizophrenics to methylphenidate infusion. ( Alvir, J; Cooper, T; Lieberman, J; Mayerhoff, D; Robinson, D, 1991) |
| "Methylphenidate hydrochloride dextroamphetamine sulfate, and levamfetamine succinate have potential as pharmacologic tools for the indirect evaluation of the role of neurotransmitters in schizophrenia." | 5.04 | Methylphenidate, dextroamphetamine, and levamfetamine. Effects on schizophrenic symptoms. ( Davis, JM; Janowsky, DS, 1976) |
| "Our aim was to summarize the efficacy and safety of atomoxetine, amphetamines, and methylphenidate in schizophrenia." | 5.01 | Systematic review and exploratory meta-analysis of the efficacy, safety, and biological effects of psychostimulants and atomoxetine in patients with schizophrenia or schizoaffective disorder. ( Carvalho, AF; Correll, CU; de Bartolomeis, A; Fornaro, M; Köhler, CA; Solmi, M; Stubbs, B; Toyoshima, K; Veronese, N, 2019) |
| " This article describes a series of cases in which clozapine provided adequate control of psychosis in women suffering schizophrenia-spectrum disorders." | 4.93 | Stimulants for impulsive violence in schizophrenia spectrum disordered women: a case series and brief review. ( Skoretz, P; Tang, C, 2016) |
| "Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate." | 4.86 | Methylphenidate-induced psychosis in adult attention-deficit/hyperactivity disorder: report of 3 new cases and review of the literature. ( Kis, B; Kraemer, M; Uekermann, J; Wiltfang, J, 2010) |
| "This study estimated the risk of developing psychotic disorders by comparing children with ADHD to non-ADHD controls, and to examine whether methylphenidate (MPH) treatment influences the risks of psychotic disorders." | 3.81 | Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan. ( Lee, SY; Lee, TL; Shyu, YC; Wang, LJ; Yang, CJ; Yang, KC; Yuan, SS, 2015) |
| "A 31-year-old male, diagnosed with schizophrenia and receiving maintenance treatment with olanzapine, was prescribed methylphenidate for comorbid attention deficit hyperactivity disorder (adhd)." | 3.76 | [Antipsychotic agents and stimulants: a judicious combination?]. ( de Jong, MH; Eussen, ML; van Gool, AR, 2010) |
| " By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level." | 2.64 | Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975) |
| "gamma-Aminobutyric acid (GABA) is an important inhibitory neurotransmitter." | 2.36 | Biochemistry and the schizophrenia. Old concepts and new hypothesis. ( Berger, PA, 1981) |
| "Methylphenidate produced an increase in psychopathology reflected by a worsening of both positive and negative symptoms." | 1.28 | Behavioral response to methylphenidate and treatment outcome in first episode schizophrenia. ( Alvir, JM; Geisler, S; Jody, D; Lieberman, JA; Szymanski, S, 1990) |
| "Although neuroleptics are the major treatment for schizophrenia, there are no effective measures to determine the appropriate or necessary length of neuroleptic maintenance." | 1.27 | Methylphenidate challenge as a predictor of relapse in schizophrenia. ( Brenner, R; Gadaleta, D; Kane, JM; Kinon, B; Lesser, MS; Lieberman, JA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (57.14) | 18.7374 |
| 1990's | 19 (24.68) | 18.2507 |
| 2000's | 4 (5.19) | 29.6817 |
| 2010's | 8 (10.39) | 24.3611 |
| 2020's | 2 (2.60) | 2.80 |
| Authors | Studies |
|---|---|
| Zhand, N | 1 |
| Harvey, P | 1 |
| Osborne, R | 1 |
| Hatko, A | 1 |
| Stuyt, M | 1 |
| Labelle, A | 1 |
| Rohde, C | 1 |
| Salagre, E | 1 |
| Nielsen, J | 1 |
| Østergaard, SD | 1 |
| Zeshan, M | 1 |
| Majeed, MH | 1 |
| Hanif, A | 1 |
| Solmi, M | 1 |
| Fornaro, M | 1 |
| Toyoshima, K | 1 |
| Carvalho, AF | 1 |
| Köhler, CA | 1 |
| Veronese, N | 1 |
| Stubbs, B | 1 |
| de Bartolomeis, A | 1 |
| Correll, CU | 1 |
| Ota, M | 2 |
| Ogawa, S | 2 |
| Kato, K | 2 |
| Wakabayashi, C | 1 |
| Kunugi, H | 2 |
| Masuda, C | 1 |
| Shyu, YC | 1 |
| Yuan, SS | 1 |
| Lee, SY | 1 |
| Yang, CJ | 1 |
| Yang, KC | 1 |
| Lee, TL | 1 |
| Wang, LJ | 1 |
| Skoretz, P | 1 |
| Tang, C | 1 |
| de Jong, MH | 1 |
| Eussen, ML | 1 |
| van Gool, AR | 1 |
| Kraemer, M | 1 |
| Uekermann, J | 1 |
| Wiltfang, J | 1 |
| Kis, B | 1 |
| RASHKIS, HA | 1 |
| SMARR, ER | 1 |
| GUNNE, LM | 1 |
| SALISBURY, BJ | 1 |
| HARE, EH | 1 |
| FERRIO, L | 1 |
| GANDIGLIO, G | 1 |
| BESUSSO, PC | 1 |
| PARGITER, RA | 1 |
| BHASKARAN, K | 1 |
| NAND, DS | 1 |
| WITTON, K | 1 |
| SOURS, JA | 1 |
| JOHNSEN, G | 1 |
| LEHMANN, HE | 1 |
| BAN, TA | 2 |
| Kishi, Y | 1 |
| Konishi, S | 1 |
| Koizumi, S | 1 |
| Kudo, Y | 1 |
| Kurosawa, H | 1 |
| Kathol, RG | 1 |
| Sharav, VH | 1 |
| Morice, E | 1 |
| Billard, JM | 1 |
| Denis, C | 1 |
| Mathieu, F | 1 |
| Betancur, C | 1 |
| Epelbaum, J | 1 |
| Giros, B | 1 |
| Nosten-Bertrand, M | 1 |
| Lieberman, JA | 11 |
| Kane, JM | 5 |
| Gadaleta, D | 2 |
| Brenner, R | 1 |
| Lesser, MS | 1 |
| Kinon, B | 1 |
| Janowsky, DS | 10 |
| Judd, LL | 4 |
| Huey, LY | 2 |
| Risch, SC | 1 |
| Segal, DS | 1 |
| Berger, PA | 1 |
| Kabes, J | 1 |
| Kotásková, H | 1 |
| Sternlicht, HC | 1 |
| Wells, SR | 1 |
| Szymanski, S | 3 |
| Alvir, JM | 4 |
| Mayerhoff, D | 2 |
| Loebel, A | 3 |
| Geisler, S | 4 |
| Chakos, M | 1 |
| Koreen, A | 1 |
| Jody, D | 5 |
| Kane, J | 1 |
| Alvir, J | 6 |
| Ramos-Lorenzi, J | 4 |
| Woerner, M | 5 |
| Novacenko, H | 2 |
| Cooper, T | 3 |
| Lieberman, J | 2 |
| Borenstein, M | 1 |
| Burke, M | 1 |
| Sebastian, CS | 1 |
| Levy, DL | 2 |
| Smith, M | 1 |
| Robinson, D | 2 |
| Lerner, G | 1 |
| Geisler, SH | 2 |
| Szymanski, SR | 1 |
| Gonzalez, A | 1 |
| Mayerhoff, DI | 3 |
| Ashtari, M | 2 |
| Bogerts, B | 2 |
| Degreef, G | 2 |
| Galynker, I | 1 |
| Ieronimo, C | 1 |
| Miner, C | 1 |
| Rosenblum, J | 1 |
| Vilkas, N | 1 |
| Rosenthal, R | 1 |
| Goldman, MB | 1 |
| Robertson, GL | 1 |
| Luchins, DJ | 1 |
| Hedeker, D | 1 |
| Pandey, GN | 3 |
| Elman, I | 1 |
| Sigler, M | 1 |
| Kronenberg, J | 1 |
| Lindenmayer, JP | 1 |
| Doron, A | 1 |
| Mendlovic, S | 1 |
| Gaoni, B | 1 |
| Szeszko, PR | 1 |
| Bilder, RM | 2 |
| Dunlop, JA | 1 |
| Walder, DJ | 1 |
| Bhat, SK | 1 |
| Galang, R | 1 |
| Davis, JM | 8 |
| Leichner, P | 3 |
| Parker, D | 2 |
| Judd, L | 1 |
| Huey, L | 5 |
| Clopton, P | 2 |
| Eggers, C | 1 |
| Zetin, M | 1 |
| Storms, L | 2 |
| Bellak, L | 1 |
| Leichner, PP | 1 |
| Reid, AE | 1 |
| Itil, TM | 1 |
| Herrmann, WM | 1 |
| Akpinar, S | 1 |
| Elmore, JL | 1 |
| Sugerman, AA | 1 |
| Gershon, S | 1 |
| Angrist, B | 1 |
| Shopsin, B | 1 |
| Devis, D | 1 |
| Carpenter, MD | 1 |
| Winsberg, BG | 1 |
| Camus, LA | 1 |
| Sharma, RP | 2 |
| Javaid, JI | 2 |
| Janicak, PG | 1 |
| Paternostro, JM | 1 |
| Easton, M | 1 |
| Little, KY | 1 |
| Gay, TL | 1 |
| Vore, M | 1 |
| Perlmutter, IR | 1 |
| Greenhill, LL | 1 |
| Chambers, W | 1 |
| Kestenbaum, CJ | 1 |
| Sarantakos, S | 2 |
| Braff, DL | 1 |
| Gadaletta, D | 2 |
| Bergmann, K | 1 |
| Wegner, J | 1 |
| Carman, JS | 1 |
| Lipton, MA | 1 |
| St Jean, A | 1 |
| Sterlin, C | 1 |
| Noe, W | 1 |
| Janowski, DS | 1 |
| El-Yousef, MK | 2 |
| el-Yousel, MK | 1 |
| Sekerke, HJ | 2 |
| Morrison, JR | 1 |
| Rappaport, M | 1 |
| Fann, WE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial Administering Estradiol Patch vs. Placebo Patch as add-on to Antipsychotics in Female Patients Above the Age of 38 With Schizophrenia, Schizoaffective or Schizophreniform Disorder[NCT04093518] | Phase 3 | 100 participants (Anticipated) | Interventional | 2019-12-02 | Recruiting | ||
| Treatment Study for Frontotemporal Dementia[NCT00088751] | 20 participants | Observational | 2004-07-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for methylphenidate and Schizophrenia
| Article | Year |
|---|---|
Systematic review and exploratory meta-analysis of the efficacy, safety, and biological effects of psychostimulants and atomoxetine in patients with schizophrenia or schizoaffective disorder.
Topics: Amphetamines; Antipsychotic Agents; Atomoxetine Hydrochloride; Attention; Executive Function; Humans | 2019 |
Stimulants for impulsive violence in schizophrenia spectrum disordered women: a case series and brief review.
Topics: Adult; Antipsychotic Agents; Central Nervous System Stimulants; Clozapine; Drug Therapy, Combination | 2016 |
Methylphenidate-induced psychosis in adult attention-deficit/hyperactivity disorder: report of 3 new cases and review of the literature.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Nervous System Stimu | 2010 |
NARCOLEPSY AND OTHER DISTURBANCES IN THE SLEEP-WAKING RHYTHM: A STUDY OF 115 CASES WITH REVIEW OF THE LITERATURE.
Topics: Black People; Cataplexy; Craniocerebral Trauma; Depression; Dextroamphetamine; Encephalitis; Halluci | 1963 |
Schizophrenia and narcolepsy: a review with a case report.
Topics: Adult; Antipsychotic Agents; Cataplexy; Central Nervous System Stimulants; Comorbidity; Diagnosis, D | 2004 |
Behavioral effects of opioid receptor antagonists in psychopathologic states.
Topics: Affective Disorders, Psychotic; Animals; beta-Endorphin; Bipolar Disorder; Clinical Trials as Topic; | 1983 |
Biochemistry and the schizophrenia. Old concepts and new hypothesis.
Topics: Acetylcholine; Amphetamine; Animals; Brain; Cocaine; Dopamine; Endorphins; gamma-Aminobutyric Acid; | 1981 |
Prediction of outcome in first-episode schizophrenia.
Topics: Antipsychotic Agents; Dopamine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Growth Hormo | 1993 |
Methylphenidate treatment of negative symptoms in patients with dementia.
Topics: Aged; Alzheimer Disease; Central Nervous System Stimulants; Cognition Disorders; Depressive Disorder | 1997 |
[Psychotropic drug therapy in children].
Topics: Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; | 1977 |
20 trials available for methylphenidate and Schizophrenia
| Article | Year |
|---|---|
Behavioral effects of opioid receptor antagonists in psychopathologic states.
Topics: Affective Disorders, Psychotic; Animals; beta-Endorphin; Bipolar Disorder; Clinical Trials as Topic; | 1983 |
Methylphenidate response, psychopathology and tardive dyskinesia as predictors of relapse in schizophrenia.
Topics: Adolescent; Adult; Blinking; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Follow-Up Studie | 1994 |
Methylphenidate increases thought disorder in recent onset schizophrenics, but not in normal controls.
Topics: Adult; Apomorphine; Brain; Dopamine; Female; Humans; Male; Methylphenidate; Psychiatric Status Ratin | 1993 |
Characteristics of patients with schizophrenia successive to childhood attention deficit hyperactivity disorder (ADHD).
Topics: Adolescent; Adult; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nerv | 1998 |
Longitudinal assessment of methylphenidate effects on oral word production and symptoms in first-episode schizophrenia at acute and stabilized phases.
Topics: Adult; Analysis of Variance; Central Nervous System Stimulants; Female; Humans; Injections, Intraven | 1999 |
The effect of methylphenidate on serum growth hormone: influence of antipsychotic drugs and diagnosis.
Topics: Adjustment Disorders; Adolescent; Adult; Alcoholism; Antipsychotic Agents; Bipolar Disorder; Blood P | 1978 |
Comparison of oral and intravenous methylphenidate.
Topics: Administration, Oral; Adult; Behavior; Blood Pressure; Clinical Trials as Topic; Female; Growth Horm | 1978 |
Methylphenidate, dextroamphetamine, and levamfetamine. Effects on schizophrenic symptoms.
Topics: Acute Disease; Amphetamines; Clinical Trials as Topic; Dextroamphetamine; Humans; Levodopa; Methylph | 1976 |
Methylphenidate hydrochloride effects on psychological tests in acute schizophrenic and nonpsychotic patients.
Topics: Acute Disease; Adult; Cognition; Female; Holtzman Inkblot Test; Humans; Male; Methylphenidate; MMPI; | 1977 |
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; | 1975 |
Prospective study of psychobiology in first-episode schizophrenia at Hillside Hospital.
Topics: Adolescent; Adult; Analysis of Variance; Apomorphine; Brain; Female; Fluphenazine; Follow-Up Studies | 1992 |
Methylphenidate augmentation therapy in schizophrenia.
Topics: Adult; Double-Blind Method; Humans; Male; Methylphenidate; Psychiatric Status Rating Scales; Schizop | 1992 |
Behavioral and biochemical effects of methylphenidate in schizophrenic and nonschizophrenic patients.
Topics: Adult; Brain; Depressive Disorder; Double-Blind Method; Female; Growth Hormone; Homovanillic Acid; H | 1991 |
Mood responses of remitted schizophrenics to methylphenidate infusion.
Topics: Adolescent; Adult; Affect; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Methyl | 1991 |
Pharmacological effects of methylphenidate on plasma homovanillic acid and growth hormone.
Topics: Adult; Affective Disorders, Psychotic; Blood Pressure; Brain; Double-Blind Method; Female; Growth Ho | 1990 |
Prediction of relapse in schizophrenia.
Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Blinking; Dopamine Antagonists; Dyskinesia | 1987 |
Methylphenidate-induced information processing dysfunction in nonschizophrenic patients.
Topics: Adult; Attention; Brain; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Methyl | 1988 |
Prediction of relapse in schizophrenia.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Humans; Methylp | 1986 |
Clinical studies with propericiazine (R.P. 8909).
Topics: Acute Disease; Adolescent; Adult; Aged; Association; Behavior; Chlorpromazine; Chronic Disease; Clin | 1967 |
Provocation of schizophrenic symptoms by intravenous administration of methylphenidate.
Topics: Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Chlorpromazine; Clinical Trials as Topic; Dopa | 1973 |
48 other studies available for methylphenidate and Schizophrenia
| Article | Year |
|---|---|
Retrospective review of use of adjunctive psychostimulants in patients with schizophrenia.
Topics: Adjuvants, Pharmaceutic; Attention; Attention Deficit Disorder with Hyperactivity; Canada; Central N | 2021 |
Use of methylphenidate and the incidence of intentional self-harm or suicide attempts among individuals with schizophrenia, bipolar disorder and personality disorder.
Topics: Bipolar Disorder; Humans; Incidence; Methylphenidate; Personality Disorders; Schizophrenia; Self-Inj | 2021 |
Successful Treatment of Catatonia with Methylphenidate in a 25-Year-Old Patient With Schizophrenia.
Topics: Adult; Catatonia; Dopamine Uptake Inhibitors; Female; Humans; Methylphenidate; Schizophrenia | 2018 |
Methamphetamine-sensitized rats show augmented dopamine release to methylphenidate stimulation: a positron emission tomography using [18F]fallypride.
Topics: Animals; Benzamides; Biomarkers; Central Nervous System Stimulants; Corpus Striatum; Disease Models, | 2015 |
Striatal and extrastriatal dopamine release in the common marmoset brain measured by positron emission tomography and [(18)F]fallypride.
Topics: Animals; Benzamides; Brain; Callithrix; Central Nervous System Stimulants; Cerebellum; Corpus Striat | 2015 |
Attention-deficit/hyperactivity disorder, methylphenidate use and the risk of developing schizophrenia spectrum disorders: A nationwide population-based study in Taiwan.
Topics: Adolescent; Age of Onset; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stim | 2015 |
[Antipsychotic agents and stimulants: a judicious combination?].
Topics: Adult; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Central | 2010 |
Drug and milieu effects with chronic schizophrenics.
Topics: Amobarbital; Catatonia; Methylphenidate; Reserpine; Schizophrenia; Trihexyphenidyl | 1957 |
[Clinical trial of ritalin].
Topics: Methylphenidate; Schizophrenia | 1957 |
Ritalin and chlorpromazine in chronic schizophrenia: a controlled clinical trial.
Topics: Chlorpromazine; Humans; Methylphenidate; Schizophrenia | 1957 |
[Stimulation analysis in schizophrenia using a new psychomimetic drug].
Topics: Methylphenidate; Schizophrenia | 1957 |
Parenteral methylphenidate hydrochloride (ritalin) in chronic underactive schizophrenics.
Topics: Methylphenidate; Schizophrenia | 1959 |
Clinical trials with alpha (2-piperidyl) benzhydrol hydrochloride (meratran) and methylphenidylate (ritalin) in chronic apathetic schizophrenics.
Topics: Benzhydryl Compounds; Methylphenidate; Piperidines; Schizophrenia | 1959 |
Directive psychotherapy with parenteral ritalin in advanced schizophrenia.
Topics: Methylphenidate; Psychotherapy; Schizophrenia | 1960 |
[CLINICAL ASPECTS OF MODEL PSYCHOSES].
Topics: Anorexia Nervosa; Convulsive Therapy; Hospitals, Psychiatric; Humans; Insulin; Lysergic Acid Diethyl | 1964 |
NOTES FROM THE LOG-BOOK OF A PSYCHOPHARMACOLOGICAL RESEARCH UNIT. II.
Topics: Antidepressive Agents; Books; Dextroamphetamine; Diazepam; Geriatrics; Humans; Mental Disorders; Met | 1964 |
The impact of the Food and Drug Administration Modernization Act on the recruitment of children for research.
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; C | 2003 |
Parallel loss of hippocampal LTD and cognitive flexibility in a genetic model of hyperdopaminergia.
Topics: Animals; Brain Diseases, Metabolic; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine | 2007 |
Methylphenidate challenge as a predictor of relapse in schizophrenia.
Topics: Adult; Antipsychotic Agents; Double-Blind Method; Female; Humans; Infusions, Parenteral; Male; Methy | 1984 |
[A contribution to differential diagnostics of functional psychoses with the use of pharmacological tests (author's transl)].
Topics: Adult; Atropine; Depressive Disorder; Diagnosis, Differential; Female; Humans; Male; Methylphenidate | 1981 |
Risperidone in childhood schizophrenia.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Drug Therapy, Combinatio | 1995 |
Gender differences in onset of illness, treatment response, course, and biologic indexes in first-episode schizophrenic patients.
Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Chronic Disease; Female; Follow-Up Studies; H | 1995 |
Time course and biologic correlates of treatment response in first-episode schizophrenia.
Topics: Adult; Antipsychotic Agents; Biomarkers; Cohort Studies; Eye Movements; Female; Growth Hormone; Huma | 1993 |
Treatment of clozapine sedation.
Topics: Adult; Clozapine; Drug Therapy, Combination; Humans; Male; Methylphenidate; Psychotic Disorders; Sch | 1993 |
Brain morphology, dopamine, and eye-tracking abnormalities in first-episode schizophrenia. Prevalence and clinical correlates.
Topics: Adolescent; Adult; Apomorphine; Biomarkers; Brain; Cohort Studies; Dopamine; Eye Movements; Female; | 1993 |
Psychotic exacerbations and enhanced vasopressin secretion in schizophrenic patients with hyponatremia and polydipsia.
Topics: Acute Disease; Adult; Arginine Vasopressin; Blood Pressure; Drinking; Female; Heart Rate; Humans; Hy | 1997 |
Narcolepsy presenting as schizophrenia.
Topics: Cataplexy; Central Nervous System Stimulants; Diagnosis, Differential; Drug Therapy, Combination; Hu | 2002 |
Critique of single amine theories: evidence of a cholinergic influence in the major mental illnesses.
Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Diso | 1975 |
Adult minimal brain dysfunction and schizophrenia: a case report.
Topics: Administration, Oral; Adult; Attention Deficit Disorder with Hyperactivity; Diagnosis, Differential; | 1978 |
Psychodiagnostic use of methylphenidate [proceedings].
Topics: Humans; Methylphenidate; Psychiatric Status Rating Scales; Remission, Spontaneous; Schizophrenia | 1977 |
A possible subgroup of the schizophrenic syndrome and implications for treatment.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys | 1976 |
Intravenous methylphenidate as a diagnostic and psychotherapeutic instrument in adult psychiatry.
Topics: Abreaction; Adult; Alcoholism; Antisocial Personality Disorder; Anxiety; Defense Mechanisms; Depress | 1976 |
Precipitation of psychosis during electroshock therapy.
Topics: Adult; Chlorpromazine; Depression; Diagnosis, Differential; Drug Therapy, Combination; Electroconvul | 1975 |
Drugs, diagnosis, and disease.
Topics: Acetylcholine; Amphetamines; Bipolar Disorder; Humans; Imipramine; Levodopa; Lithium; Methylphenidat | 1975 |
[Release of dopamine and symptoms of schizophrenia].
Topics: Amphetamine; Dextroamphetamine; Dopamine; Humans; Methylphenidate; Norepinephrine; Schizophrenia | 1975 |
Working in psychiatric research: answers tomorrow, dilemmas today.
Topics: Adolescent; Apomorphine; Clinical Protocols; Countertransference; Drug Therapy, Combination; Humans; | 1991 |
Behavioral response to methylphenidate and treatment outcome in first episode schizophrenia.
Topics: Adolescent; Adult; Behavior; Humans; Methylphenidate; Schizophrenia; Schizophrenic Psychology | 1990 |
Predictors of response to high dose antipsychotics in chronic schizophrenics.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, Drug; Female; Hallucinatio | 1989 |
Childhood schizophrenia: theoretical and treatment issues.
Topics: Child; Humans; Male; Methylphenidate; Schizophrenia | 1989 |
Methylphenidate challenge tests and course of schizophrenia.
Topics: Adolescent; Adult; Female; Growth Hormone; Humans; Male; Methylphenidate; Middle Aged; Prognosis; Pr | 1985 |
Methylphenidate in akathisia.
Topics: Adult; Humans; Hyperkinesis; Male; Methylphenidate; Schizophrenia; Tranquilizing Agents | 1972 |
Neuropsychopharmacology of monoamines and their regulatory enzymes.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Biogenic Amines; Brain; Cocaine; Dextroamphe | 1974 |
Proceedings: Effect of intravenous d-amphetamine, 1-amphetamine and methylphenidate in schizophrenics.
Topics: Amphetamine; Behavior; Dextroamphetamine; Hemodynamics; Humans; Methylphenidate; Psychiatric Status | 1974 |
A two factor theory of schizophrenia.
Topics: Acetylcholine; Amphetamine; Animals; Bipolar Disorder; Brain; Dextroamphetamine; Dopamine; Dose-Resp | 1974 |
Antagonistic effects of physostigmine and methylphenidate in man.
Topics: Affective Symptoms; Behavior; Bipolar Disorder; Humans; Inhibition, Psychological; Methylphenidate; | 1973 |
Letter: Hereditary factors in hyperkinesis.
Topics: Family; Genetic Diseases, Inborn; Humans; Hyperkinesis; Methylphenidate; Psychoses, Substance-Induce | 1974 |
Attention to competing voice messages by nonacute schizophrenic patients. Effects of message load, drugs, dosage levels and patient background.
Topics: Acute Disease; Adult; Attention; Auditory Perception; Chlorpromazine; Chronic Disease; Dextroampheta | 1968 |
Use of methylphenidate to counteract acute dystonic effects of phenothiazines.
Topics: Adult; Humans; Male; Methylphenidate; Movement Disorders; Perphenazine; Schizophrenia; Torticollis; | 1966 |