Page last updated: 2024-10-31

methylphenidate and Sarcoidosis

methylphenidate has been researched along with Sarcoidosis in 4 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.

Research Excerpts

ExcerptRelevanceReference
"The Fatigue and Sarcoidosis-Treatment with Methylphenidate study is a randomised, controlled, parallel-arm and feasibility trial of methylphenidate for the treatment of sarcoidosis-associated fatigue."9.24Feasibility study of a randomised controlled trial to investigate the treatment of sarcoidosis-associated fatigue with methylphenidate (FaST-MP): a study protocol. ( Atkins, C; Clark, AB; Fordham, R; Jones, AP; Stockl, A; Wilson, AM, 2017)
"The Fatigue and Sarcoidosis-Treatment with Methylphenidate study is a randomised, controlled, parallel-arm and feasibility trial of methylphenidate for the treatment of sarcoidosis-associated fatigue."5.24Feasibility study of a randomised controlled trial to investigate the treatment of sarcoidosis-associated fatigue with methylphenidate (FaST-MP): a study protocol. ( Atkins, C; Clark, AB; Fordham, R; Jones, AP; Stockl, A; Wilson, AM, 2017)
"Trial evidence for treating fatigue as a manifestation of sarcoidosis is limited and requires further investigation."2.55Managing fatigue in sarcoidosis - A systematic review of the evidence. ( Atkins, C; Wilson, AM, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Atkins, C3
Jones, A1
Clark, AB2
Stockl, A2
Fordham, R2
Wilson, AM3
Jones, AP1
Wagner, MT1
Marion, SD1
Judson, MA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fatigue in Sarcoidosis - A Feasibility Study Investigating the Treatment of Fatigue in Stable Sarcoidosis Patients Using Methylphenidate[NCT02643732]30 participants (Anticipated)Interventional2016-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methylphenidate and Sarcoidosis

ArticleYear
Managing fatigue in sarcoidosis - A systematic review of the evidence.
    Chronic respiratory disease, 2017, Volume: 14, Issue:2

    Topics: Adalimumab; Antirheumatic Agents; Benzhydryl Compounds; Central Nervous System Stimulants; Exercise

2017

Trials

3 trials available for methylphenidate and Sarcoidosis

ArticleYear
Feasibility of investigating methylphenidate for the treatment of sarcoidosis-associated fatigue (the FaST-MP study): a double-blind, parallel-arm randomised feasibility trial.
    BMJ open respiratory research, 2021, Volume: 8, Issue:1

    Topics: Double-Blind Method; Fatigue; Feasibility Studies; Humans; Methylphenidate; Sarcoidosis

2021
Feasibility study of a randomised controlled trial to investigate the treatment of sarcoidosis-associated fatigue with methylphenidate (FaST-MP): a study protocol.
    BMJ open, 2017, Dec-04, Volume: 7, Issue:12

    Topics: Central Nervous System Stimulants; Chronic Disease; Double-Blind Method; England; Fatigue; Feasibili

2017
The effects of fatigue and treatment with methylphenidate on sustained attention in sarcoidosis.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2005, Volume: 22, Issue:3

    Topics: Algorithms; Attention; Central Nervous System Stimulants; Fatigue; Female; Humans; Male; Methylpheni

2005