methylphenidate has been researched along with Sarcoidosis, Pulmonary in 2 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Sarcoidosis, Pulmonary: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fatigue is a common complaint in patients with sarcoidosis." | 6.73 | Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue. ( Baughman, RP; Harman, S; Lower, EE, 2008) |
| "Fatigue is a common complaint in patients with sarcoidosis." | 2.73 | Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue. ( Baughman, RP; Harman, S; Lower, EE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tachibana, T | 1 |
| Iwai, K | 1 |
| Takemura, T | 1 |
| Lower, EE | 1 |
| Harman, S | 1 |
| Baughman, RP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fatigue in Sarcoidosis - A Feasibility Study Investigating the Treatment of Fatigue in Stable Sarcoidosis Patients Using Methylphenidate[NCT02643732] | 30 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting | |||
| Randomized, Double-Blind, Placebo-Controlled Study of Dexmethylphenidate Hydrochloride, (d-MPH) in the Treatment of Fatigue in Sarcoidosis Subjects.[NCT00361387] | Phase 4 | 12 participants (Anticipated) | Interventional | 2006-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methylphenidate and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Sarcoidosis in the aged: review and management.
Topics: Age Factors; Aged; Aged, 80 and over; Bosentan; Humans; Incidence; Methylphenidate; Sarcoidosis, Pul | 2010 |
1 trial available for methylphenidate and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue.
Topics: Adult; Aged; Central Nervous System Stimulants; Cross-Over Studies; Dexmethylphenidate Hydrochloride | 2008 |
Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue.
Topics: Adult; Aged; Central Nervous System Stimulants; Cross-Over Studies; Dexmethylphenidate Hydrochloride | 2008 |
Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue.
Topics: Adult; Aged; Central Nervous System Stimulants; Cross-Over Studies; Dexmethylphenidate Hydrochloride | 2008 |
Double-blind, randomized trial of dexmethylphenidate hydrochloride for the treatment of sarcoidosis-associated fatigue.
Topics: Adult; Aged; Central Nervous System Stimulants; Cross-Over Studies; Dexmethylphenidate Hydrochloride | 2008 |