methylphenidate has been researched along with Psychoses, Drug in 39 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate." | 4.86 | Methylphenidate-induced psychosis in adult attention-deficit/hyperactivity disorder: report of 3 new cases and review of the literature. ( Kis, B; Kraemer, M; Uekermann, J; Wiltfang, J, 2010) |
| " While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs." | 2.49 | Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. ( Banaschewski, T; Buitelaar, J; Coghill, D; Cortese, S; Danckaerts, M; Dittmann, RW; Graham, J; Holtmann, M; Sergeant, J; Taylor, E, 2013) |
| "Amphetamine use was associated with a greater risk of psychosis than methylphenidate." | 1.51 | Psychosis with Methylphenidate or Amphetamine in Patients with ADHD. ( Castro, VM; Hsu, J; Moran, LV; Ongur, D; Perlis, RH; Schneeweiss, S, 2019) |
| " Antidepressant medications, both TCAs and MAOIs, often help relieve the symptoms of depression that emerge when chronic use of cocaine is discontinued." | 1.27 | Cocaine abuse and its treatment. ( Resnick, EB; Resnick, RB, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (46.15) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 12 (30.77) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Kooij, JJS | 1 |
| Martínez-Aguayo, JC | 1 |
| Arancibia, M | 1 |
| Meza-Concha, N | 1 |
| Bustamante, C | 1 |
| Pérez-Bracchiglione, J | 1 |
| Madrid, E | 1 |
| Espadas, M | 1 |
| Insa, I | 1 |
| Chamorro, M | 1 |
| Alda-Diez, JA | 1 |
| Moran, LV | 1 |
| Ongur, D | 1 |
| Hsu, J | 1 |
| Castro, VM | 1 |
| Perlis, RH | 1 |
| Schneeweiss, S | 1 |
| Hollis, C | 2 |
| Chen, Q | 1 |
| Chang, Z | 1 |
| Quinn, PD | 1 |
| Viktorin, A | 1 |
| Lichtenstein, P | 1 |
| D'Onofrio, B | 1 |
| Landén, M | 1 |
| Larsson, H | 1 |
| Merrill, RM | 1 |
| Thygerson, SM | 1 |
| Palmer, CA | 1 |
| Man, KK | 1 |
| Coghill, D | 2 |
| Chan, EW | 1 |
| Lau, WC | 1 |
| Liddle, E | 1 |
| Banaschewski, T | 2 |
| McCarthy, S | 1 |
| Neubert, A | 1 |
| Sayal, K | 1 |
| Ip, P | 1 |
| Wong, IC | 1 |
| Kraemer, M | 1 |
| Uekermann, J | 1 |
| Wiltfang, J | 1 |
| Kis, B | 1 |
| Ekinci, O | 1 |
| Sabuncuoglu, O | 1 |
| Fernández-Fernández, MA | 1 |
| Rufo-Campos, M | 1 |
| Mateos-Checa, R | 1 |
| Muñoz-Cabello, B | 1 |
| Madruga-Garrido, M | 1 |
| Blanco-Martínez, B | 1 |
| Grau-López, L | 1 |
| Roncero, C | 1 |
| Navarro, MC | 1 |
| Casas, M | 1 |
| Pereiro Gómez, C | 1 |
| Vicente-Alba, J | 1 |
| Ramos-Caneda, A | 1 |
| Vázquez Ventoso, C | 1 |
| Fontela-Vivanco, E | 1 |
| Díaz del Valle, JC | 1 |
| Cortese, S | 1 |
| Holtmann, M | 1 |
| Buitelaar, J | 1 |
| Danckaerts, M | 1 |
| Dittmann, RW | 1 |
| Graham, J | 1 |
| Taylor, E | 1 |
| Sergeant, J | 1 |
| Mahowald, MW | 2 |
| Bornemann, MA | 1 |
| Ross, RG | 1 |
| Caci, H | 1 |
| Baylé, F | 1 |
| Greiner, C | 1 |
| Enss, E | 1 |
| Haen, E | 1 |
| Gerlach, J | 1 |
| Bjørndal, N | 1 |
| Christensson, E | 1 |
| Resnick, RB | 1 |
| Resnick, EB | 1 |
| Pawluk, LK | 1 |
| Hurwitz, TD | 1 |
| Schluter, JL | 1 |
| Ullevig, C | 1 |
| Koreen, AR | 1 |
| Lieberman, JA | 1 |
| Alvir, J | 1 |
| Chakos, M | 1 |
| Numachi, Y | 1 |
| Yoshida, S | 1 |
| Matsuoka, H | 1 |
| Sato, M | 1 |
| Cherland, E | 1 |
| Fitzpatrick, R | 1 |
| Rosenfeld, AA | 1 |
| Allen, RP | 1 |
| Safer, D | 1 |
| Covi, L | 1 |
| Gershon, S | 2 |
| Angrist, B | 2 |
| Shopsin, B | 1 |
| Eisenberg, L | 1 |
| Fog, R | 1 |
| Janowksy, DS | 1 |
| el-Yousef, MK | 1 |
| Davis, JM | 1 |
| Sekerke, HJ | 1 |
| Hasse, HE | 1 |
| Schönhöfer, PS | 1 |
| Waldmann, H | 1 |
| Morrison, JR | 1 |
| Ziolko, HU | 1 |
| Kuipers, F | 1 |
| Spensley, J | 2 |
| Rockwell, DA | 1 |
| Rozberg, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Therapeutic Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Pediatric Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Cohorts (ADHD): a Randomized, Sham-controlled Study.[NCT06069323] | 80 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for methylphenidate and Psychoses, Drug
| Article | Year |
|---|---|
Brief psychosis induced by methylphenidate in a child with attention deficit disorder: a case report and literature review.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Mal | 2017 |
[Side effects of methylphenidate in children and the young].
Topics: Adolescent; Anorexia; Attention Deficit Disorder with Hyperactivity; Bone Diseases, Developmental; C | 2018 |
Methylphenidate-induced psychosis in adult attention-deficit/hyperactivity disorder: report of 3 new cases and review of the literature.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Nervous System Stimu | 2010 |
Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressure | 2013 |
[Neurotoxicity of psychostimulants].
Topics: Amphetamine; Brain; Central Nervous System Stimulants; Depression, Chemical; Dopamine; Humans; Methy | 1999 |
Effects of psychostimulants on aggression.
Topics: Adolescent; Aggression; Amphetamine; Animals; Child; Dextroamphetamine; Dogs; Dose-Response Relation | 1975 |
Dopamine and psychotic states: preliminary remarks.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carbon Radioisotopes; Cats; Cocaine; Dihydroxyp | 1974 |
On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Caffeine; Catalepsy; Cocaine; Compulsive Behavior; Corpus Stria | 1972 |
2 trials available for methylphenidate and Psychoses, Drug
| Article | Year |
|---|---|
The behavioral effect of m-chlorophenylpiperazine (mCPP) and methylphenidate in first-episode schizophrenia and normal controls.
Topics: Adolescent; Adult; Behavior; Dopamine Uptake Inhibitors; Female; Humans; Infusions, Intravenous; Mal | 1997 |
[Personality dependant changes in the experimental psychosis induced by lysergic acid diethylamide].
Topics: Adult; Clinical Trials as Topic; Euphoria; Fear; Female; Humans; Lysergic Acid Diethylamide; Meclofe | 1966 |
29 other studies available for methylphenidate and Psychoses, Drug
| Article | Year |
|---|---|
[Risk of psychosis with treatment for ADHD].
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2020 |
Psychosis with Methylphenidate or Amphetamine in Patients with ADHD.
Topics: Adolescent; Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous Syste | 2019 |
Methylphenidate and the risk of psychosis in adolescents and young adults: a population-based cohort study.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Cohort Studies; Female; Humans; In | 2019 |
Risk of Injury According to Attention Deficit Hyperactivity Disorder, Comorbid Mental Illness, and Medication Therapy.
Topics: Adolescent; Adult; Amphetamine; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperacti | 2016 |
Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system.
Topics: Adolescent; Child; Electronic Health Records; Female; Follow-Up Studies; Hallucinations; Hong Kong; | 2016 |
Psychosis associated with switching from risperidone to aripiprazole in an adolescent on methylphenidate treatment.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Central Nervous System Stimulants; Humans; Male; Met | 2011 |
[Infantile psychosis secondary to methylphenidate].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Mal | 2011 |
Psychosis induced by the interaction between disulfiram and methylphenidate may be dose dependent.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Disulfiram; Dopamin | 2012 |
[Ekbom syndrome in an intravenous methylphenidate abuser].
Topics: Central Nervous System Stimulants; Delusional Parasitosis; Humans; Male; Methylphenidate; Middle Age | 2012 |
Stimulants and narcolepsy.
Topics: Central Nervous System Stimulants; Dose-Response Relationship, Drug; Humans; Methylphenidate; Narcol | 2005 |
Psychotic and manic-like symptoms during stimulant treatment of attention deficit hyperactivity disorder.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Ne | 2006 |
A case of disulfiram-methylphenidate interaction: implications for treatment.
Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Disulfiram; Dopamine beta-Hydroxyl | 2007 |
[Drug-induced psychosis after intake of a modified--release formulation of methylphenidate].
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Diagnosis, Differential; Dose-Response Re | 2009 |
Methylphenidate, apomorphine, THIP, and diazepam in monkeys: dopamine-GABA behavior related to psychoses and tardive dyskinesia.
Topics: Animals; Apomorphine; Chlorocebus aethiops; Diazepam; Dopamine; Drug Interactions; Dyskinesia, Drug- | 1984 |
Cocaine abuse and its treatment.
Topics: Antidepressive Agents; Behavior Therapy; Cocaine; Cognition; Conditioning, Psychological; Diazepam; | 1984 |
Psychiatric morbidity in narcoleptics on chronic high dose methylphenidate therapy.
Topics: Adult; Causality; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Male; Methy | 1995 |
Psychotic side effects of psychostimulants: a 5-year review.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Pres | 1999 |
Depression and psychotic regression following prolonged methylphenidate use and withdrawal: case report.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Depression; Humans; Male; Methylphenidate; Psy | 1979 |
Drugs, diagnosis, and disease.
Topics: Acetylcholine; Amphetamines; Bipolar Disorder; Humans; Imipramine; Levodopa; Lithium; Methylphenidat | 1975 |
Symposium: behavior modification by drugs. 3. The clinical use of stimulant drugs in children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Feeding and Eat | 1972 |
Amphetamine-type drugs for hyperactive children.
Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Body Weight; Brain; Child; Dextroamphetamin | 1972 |
Cholinergic antagonism of methylphenidate-induced stereotyped behavior.
Topics: Animals; Behavior, Animal; Drug Antagonism; Humans; Male; Methylphenidate; Neostigmine; Physostigmin | 1972 |
[Significance of amphetamine-like drugs in the psychodynamics of drug abuse in juveniles].
Topics: Adult; Amphetamine; Female; Hallucinations; Humans; Male; Methylphenidate; Psychoses, Substance-Indu | 1973 |
Letter: Hereditary factors in hyperkinesis.
Topics: Family; Genetic Diseases, Inborn; Humans; Hyperkinesis; Methylphenidate; Psychoses, Substance-Induce | 1974 |
[Hallucination as side effect of methylphenidate].
Topics: Adolescent; Female; Hallucinations; Humans; Methylphenidate; Psychoses, Substance-Induced | 1972 |
Psychosis during methylphenidate abuse.
Topics: Adult; Female; Humans; Injections, Intravenous; Male; Methylphenidate; Paranoid Disorders; Psychoses | 1972 |
Folie à deux with methylphenidate psychosis.
Topics: Adult; Female; Humans; Interpersonal Relations; Male; Methylphenidate; Paranoid Disorders; Psychoses | 1972 |
[Folie à deux associated with methylphenidate addiction].
Topics: Adult; Family Characteristics; Female; Humans; Male; Methylphenidate; Personality Assessment; Psycho | 1971 |
Drugs for depression.
Topics: Amphetamine; Antidepressive Agents; Humans; Methylphenidate; Monoamine Oxidase Inhibitors; Obesity; | 1968 |