methylphenidate has been researched along with Psychomotor Agitation in 20 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data." | 5.14 | Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity. ( Aman, MG; Arnold, LE; Ghuman, J; Jahromi, LB; Kasari, CL; Kustan, E; Lee, LS; McCracken, JT; McDougle, CJ; Posey, DJ; Ritz, L; Scahill, L; Tierney, E; Vitiello, B; Witwer, A, 2009) |
| "The use of the atypical neuroleptic medication, risperidone, may be considered as part of the armamentarium available to physicians treating restlessness in severe brain injuries." | 3.72 | Risperidone treatment of motor restlessness following anoxic brain injury. ( Collins, L; Silver, BV; Zidek, KA, 2003) |
| "Neurobehavioural sequelae of traumatic brain injuries require an appropriate/effective pharmacological response in that they represent an important cause of disability." | 1.35 | Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury. ( Lombardi, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 12 (60.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bioulac, S | 1 |
| Micoulaud-Franchi, JA | 1 |
| Maire, J | 1 |
| Bouvard, MP | 1 |
| Rizzo, AA | 1 |
| Sagaspe, P | 1 |
| Philip, P | 1 |
| Luauté, J | 1 |
| Plantier, D | 1 |
| Wiart, L | 1 |
| Tell, L | 1 |
| Jahromi, LB | 1 |
| Kasari, CL | 1 |
| McCracken, JT | 1 |
| Lee, LS | 1 |
| Aman, MG | 1 |
| McDougle, CJ | 1 |
| Scahill, L | 1 |
| Tierney, E | 1 |
| Arnold, LE | 1 |
| Vitiello, B | 1 |
| Ritz, L | 1 |
| Witwer, A | 1 |
| Kustan, E | 1 |
| Ghuman, J | 1 |
| Posey, DJ | 1 |
| Carter, G | 1 |
| Bagdure, DN | 1 |
| Bhoite, GR | 1 |
| Reiter, PD | 1 |
| Dobyns, EL | 1 |
| Klein-Schwartz, W | 1 |
| McGrath, J | 1 |
| Silver, BV | 1 |
| Collins, L | 1 |
| Zidek, KA | 1 |
| Richard, I | 1 |
| Perrouin-Verbe, B | 1 |
| Rome, J | 1 |
| Bernat, C | 1 |
| Mathé, JF | 1 |
| EISENBERG, L | 1 |
| Cummings, MR | 1 |
| Miller, BD | 1 |
| Kratochvil, CJ | 1 |
| Varley, C | 1 |
| Cummins, TK | 1 |
| Martin, A | 1 |
| Fleminger, S | 1 |
| Greenwood, RJ | 1 |
| Oliver, DL | 1 |
| Sabuncuoglu, O | 1 |
| Lombardi, F | 1 |
| Melnick, SM | 1 |
| Hinshaw, SP | 1 |
| Weisfelt, M | 1 |
| Schrier, AC | 1 |
| de Leeuw, MC | 1 |
| Rosati, DL | 1 |
| Weinberg, WA | 1 |
| Brumback, RA | 1 |
| Haas, JF | 1 |
| Cope, DN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability: A Randomized, Double-Blind, Placebo-Controlled Trial[NCT00627250] | 76 participants (Actual) | Interventional | 2003-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for methylphenidate and Psychomotor Agitation
| Article | Year |
|---|---|
Care management of the agitation or aggressiveness crisis in patients with TBI. Systematic review of the literature and practice recommendations.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anti-Anxiety Agents; Anticonvulsants; Antipsych | 2016 |
[Pharmacological treatment of post-traumatic behavioural disorders].
Topics: Adrenergic beta-Antagonists; Aggression; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agent | 2003 |
Pharmacologic management of behavioral instability in medically ill pediatric patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Aggression; Analgesics, Non-Narcotic; Behavior Therapy; Behav | 2004 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2006 |
[Hyperactive behavior in adults; possibly attention deficit/hyperactivity disorder (ADHD)].
Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; | 2001 |
3 trials available for methylphenidate and Psychomotor Agitation
| Article | Year |
|---|---|
Virtual Remediation Versus Methylphenidate to Improve Distractibility in Children With ADHD: A Controlled Randomized Clinical Trial Study.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Met | 2020 |
Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity.
Topics: Adolescent; Asperger Syndrome; Autistic Disorder; Central Nervous System Stimulants; Child; Child De | 2009 |
What they want and what they get: the social goals of boys with ADHD and comparison boys.
Topics: Aggression; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 1996 |
12 other studies available for methylphenidate and Psychomotor Agitation
| Article | Year |
|---|---|
A washout period needed before switching from a neuroleptic to an amphetamine.
Topics: Adolescent; Amphetamines; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child | 2009 |
Animal behavior case of the month. Hyperactivity.
Topics: Animals; Anti-Anxiety Agents; Behavior Therapy; Behavior, Animal; Clonazepam; Dogs; Male; Methylphen | 2011 |
Dexmedetomidine in a child with methylphenidate intoxication.
Topics: Accidents, Home; Central Nervous System Stimulants; Child; Dexmedetomidine; Female; Humans; Hypnotic | 2013 |
Poison centers' experience with methylphenidate abuse in pre-teens and adolescents.
Topics: Adolescent; Adult; Child; Female; Humans; Hypertension; Male; Methylphenidate; Poison Control Center | 2003 |
Risperidone treatment of motor restlessness following anoxic brain injury.
Topics: Adolescent; Amantadine; Brain Injuries; Dopamine Agents; Drug Therapy, Combination; Humans; Hypoxia, | 2003 |
DRUG THERAPY OF OVERACTIVITY IN CHILDREN (BRIEF SUMMARY OF REMARKS).
Topics: Child; Dextromoramide; Humans; Methylphenidate; Movement Disorders; Psychomotor Agitation; Psychopha | 1963 |
Less is more: inpatient management of a child with complex pharmacotherapy.
Topics: Aggression; Amphetamines; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Depressio | 2006 |
Risperidone-to-methylphenidate switch reaction in children: three cases.
Topics: Adolescent; Akathisia, Drug-Induced; Antipsychotic Agents; Attention Deficit and Disruptive Behavior | 2007 |
Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury.
Topics: Amantadine; Animals; Antidepressive Agents; Antipsychotic Agents; Brain Injuries; Cognition; Cogniti | 2008 |
Early polyneuropharmacologic intervention in brain injury agitation.
Topics: Adolescent; Adult; Amantadine; Antipsychotic Agents; Brain Injuries; Dextroamphetamine; Drug Adminis | 2002 |
Primary disorder of vigilance: a novel explanation of inattentiveness, daydreaming, boredom, restlessness, and sleepiness.
Topics: Arousal; Attention; Attention Deficit Disorder with Hyperactivity; Boredom; Child; Child Behavior Di | 1990 |
Neuropharmacologic management of behavior sequelae in head injury: a case report.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Behavior; Craniocerebral Trauma; Human | 1985 |