methylphenidate has been researched along with Prader-Willi Syndrome in 4 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Prader-Willi Syndrome: An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antipsychotics, particularly risperidone, appear to be effective in reducing problem behaviors in children with intellectual disability." | 4.93 | Pharmacotherapy for mental health problems in people with intellectual disability. ( Findling, RL; Ji, NY, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, NY | 1 |
| Findling, RL | 1 |
| Martin, A | 1 |
| State, M | 1 |
| Koenig, K | 1 |
| Schultz, R | 1 |
| Dykens, EM | 1 |
| Cassidy, SB | 1 |
| Leckman, JF | 1 |
| Jerome, L | 2 |
1 review available for methylphenidate and Prader-Willi Syndrome
| Article | Year |
|---|---|
Pharmacotherapy for mental health problems in people with intellectual disability.
Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Ce | 2016 |
3 other studies available for methylphenidate and Prader-Willi Syndrome
| Article | Year |
|---|---|
Prader-Willi syndrome.
Topics: Child; Chromosome Deletion; Female; Fluvoxamine; Human Growth Hormone; Humans; In Situ Hybridization | 1998 |
Pharmacotherapy of eating and behavioral problems.
Topics: Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluoxetine; Humans; Male; Met | 1991 |
Pharmacotherapeutic approaches for Prader-Willi Syndrome.
Topics: Appetite; Body Weight; Child; Humans; Male; Methylphenidate; Prader-Willi Syndrome | 1989 |