methylphenidate has been researched along with Post-Concussion Syndrome in 5 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Post-Concussion Syndrome: The organic and psychogenic disturbances observed after closed head injuries (HEAD INJURIES, CLOSED). Post-concussion syndrome includes subjective physical complaints (i.e. headache, dizziness), cognitive, emotional, and behavioral changes. These disturbances can be chronic, permanent, or late emerging.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate was tested in each patient using three treatment strategies: no medication, low dose (5 mg × 3) and normal dose (20 mg × 3) for 4 weeks using a randomized cross-over design." | 6.79 | Evaluation of dosage, safety and effects of methylphenidate on post-traumatic brain injury symptoms with a focus on mental fatigue and pain. ( Andréll, P; Johansson, B; Mannheimer, C; Odenstedt, J; Rönnbäck, L; Wentzel, AP, 2014) |
| "Thirty participants who suffered from long-term post-concussion symptoms after a mild TBI or moderate TBI and who had reported positive effects with methylphenidate during an initial phase of this follow-up study were treated with methylphenidate for a further six months." | 5.24 | Long-term treatment with methylphenidate for fatigue after traumatic brain injury. ( Andréll, P; Johansson, B; Mannheimer, C; Rönnbäck, L; Wentzel, AP, 2017) |
| "Methylphenidate was tested in each patient using three treatment strategies: no medication, low dose (5 mg × 3) and normal dose (20 mg × 3) for 4 weeks using a randomized cross-over design." | 2.79 | Evaluation of dosage, safety and effects of methylphenidate on post-traumatic brain injury symptoms with a focus on mental fatigue and pain. ( Andréll, P; Johansson, B; Mannheimer, C; Odenstedt, J; Rönnbäck, L; Wentzel, AP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quinn, DK | 1 |
| Mayer, AR | 1 |
| Master, CL | 1 |
| Fann, JR | 1 |
| Johansson, B | 3 |
| Wentzel, AP | 3 |
| Andréll, P | 3 |
| Rönnbäck, L | 3 |
| Mannheimer, C | 3 |
| Odenstedt, J | 1 |
| Lee, H | 1 |
| Kim, SW | 1 |
| Kim, JM | 1 |
| Shin, IS | 1 |
| Yang, SJ | 1 |
| Yoon, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exercise Training in Depressed Traumatic Brain Injury Survivors[NCT01805479] | 0 participants (Actual) | Interventional | 2013-02-28 | Withdrawn (stopped due to Unable to enroll participants. Sponsor requested study closure.) | |||
| Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417] | Phase 2 | 120 participants (Anticipated) | Interventional | 2022-05-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for methylphenidate and Post-Concussion Syndrome
| Article | Year |
|---|---|
Evaluation of dosage, safety and effects of methylphenidate on post-traumatic brain injury symptoms with a focus on mental fatigue and pain.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Cross-Over Studies; Dose-Response Relationship | 2014 |
Long-term treatment with methylphenidate for fatigue after traumatic brain injury.
Topics: Adult; Attention; Brain Injuries, Traumatic; Central Nervous System Stimulants; Cognition; Female; H | 2017 |
Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Cognition Disorders; Depression; Do | 2005 |
Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Cognition Disorders; Depression; Do | 2005 |
Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Cognition Disorders; Depression; Do | 2005 |
Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Cognition Disorders; Depression; Do | 2005 |
2 other studies available for methylphenidate and Post-Concussion Syndrome
| Article | Year |
|---|---|
Prolonged Postconcussive Symptoms.
Topics: Accidents, Traffic; Adaptation, Psychological; Anxiety Disorders; Attention; Axons; Brain Concussion | 2018 |
Two-Year Methylphenidate Treatment of Mental Fatigue and Cognitive Function After a Traumatic Brain Injury: A Clinical Prospective Study.
Topics: Adult; Brain Injuries, Traumatic; Central Nervous System Stimulants; Cognitive Dysfunction; Female; | 2018 |