Page last updated: 2024-10-31

methylphenidate and Poisoning

methylphenidate has been researched along with Poisoning in 15 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"Patients aged 5-18 years with a methylphenidate (MPH) prescription and an incident poisoning diagnosis between January 2001 and June 2020 were identified from the Hong Kong Clinical Data Analysis and Reporting System."8.02Treatment with Methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) and the Risk of All-Cause Poisoning in Children and Adolescents: A Self-Controlled Case Series Study. ( Chan, EW; Chui, CSL; Coghill, D; Gao, L; Hon, KL; Ip, P; Li, X; Lum, TYS; Man, KKC; Tse, ML; Wong, ICK; Wong, KHTW, 2021)
"Patients aged 5-18 years with a methylphenidate (MPH) prescription and an incident poisoning diagnosis between January 2001 and June 2020 were identified from the Hong Kong Clinical Data Analysis and Reporting System."4.02Treatment with Methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) and the Risk of All-Cause Poisoning in Children and Adolescents: A Self-Controlled Case Series Study. ( Chan, EW; Chui, CSL; Coghill, D; Gao, L; Hon, KL; Ip, P; Li, X; Lum, TYS; Man, KKC; Tse, ML; Wong, ICK; Wong, KHTW, 2021)
"Ethylphenidate is a stimulant novel psychoactive substance that is an analogue of the prescription drug methylphenidate (Ritalin(®))."1.43Seven fatalities associated with ethylphenidate. ( Cole, R; Hikin, L; Maskell, PD; Morley, SR; Smith, PR, 2016)
"Methylphenidate exposure was associated with symptom development in 31% of cases."1.31Characterization of methylphenidate exposures reported to a regional poison control center. ( White, SR; Yadao, CM, 2000)
"Methylphenidate abuse was common among adolescents and adults."1.31A profile of methylphenidate exposures. ( Foley, R; Krenzelok, EP; Mrvos, R, 2000)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's2 (13.33)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Gao, L1
Man, KKC1
Chan, EW1
Chui, CSL1
Li, X1
Coghill, D1
Hon, KL1
Tse, ML1
Lum, TYS1
Wong, KHTW1
Ip, P1
Wong, ICK1
Jensen, LS1
Pagsberg, AK1
Dalhoff, K1
Hondebrink, L1
Rietjens, SJ1
Hunault, CC1
Pereira, RR1
Kelleci, N1
Yasar, G1
Ghebreslasie, A1
Lo-A-Foe, C1
De Vries, I1
Meulenbelt, J1
Maskell, PD1
Smith, PR1
Cole, R1
Hikin, L1
Morley, SR1
LoVecchio, F1
Ozimek, J1
Sawyers, B1
Thole, D1
HOAGLAND, RJ2
McCARTY, RJ1
PLUMB, RL1
JOSEPH, SW1
Bailey, B1
Letarte, A1
Abran, MC1
Bastecký, J1
Wax, PM1
White, SR1
Yadao, CM1
Foley, R1
Mrvos, R1
Krenzelok, EP1
Comstock, EG1
Murphree, HB1

Other Studies

15 other studies available for methylphenidate and Poisoning

ArticleYear
Treatment with Methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) and the Risk of All-Cause Poisoning in Children and Adolescents: A Self-Controlled Case Series Study.
    CNS drugs, 2021, Volume: 35, Issue:7

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2021
Methylphenidate misuse in adult patients and the impact of therapeutic use.
    Human & experimental toxicology, 2015, Volume: 34, Issue:5

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Data Interp

2015
Methylphenidate intoxications in children and adults: exposure circumstances and evidence-based dose threshold for pre-hospital triage.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Central Nervous System Stimulants; Child; Child, Preschool; Dose-Response Relatio

2015
Seven fatalities associated with ethylphenidate.
    Forensic science international, 2016, Volume: 265

    Topics: Adult; Central Nervous System Stimulants; Diagnosis, Differential; Fatal Outcome; Forensic Pathology

2016
Outcomes after accidental pediatric ingestions of (dextro)amphetamine and methylphenidate.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:8

    Topics: Accidents; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimul

2009
Treatment of drug-induced coma: effectiveness of methylphenidate.
    The American journal of the medical sciences, 1963, Volume: 245

    Topics: Coma; Humans; Methylphenidate; Poisoning; Suicide

1963
INGESTION OF A TOXIC OVERDOSE OF CHLORPROTHIXENE BY A 3 YEAR OLD.
    The Journal of pediatrics, 1964, Volume: 65

    Topics: Child; Chlorprothixene; Drug Therapy; Eating; Methylphenidate; Neurologic Manifestations; Phenobarbi

1964
PHARMACOLOGIC TREATMENT OF COMA OF DIVERSE ORIGIN.
    The American journal of the medical sciences, 1965, Volume: 249

    Topics: Acidosis; Antitoxins; Asphyxia Neonatorum; Cerebral Hemorrhage; Coma; Craniocerebral Trauma; Diabeti

1965
Methylphenidate unintentional ingestion in preschool children.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:3

    Topics: Child, Preschool; Female; Humans; Infant; Male; Methylphenidate; Poisoning

2005
[Methylphenidate (Ritalin) in the treatment of acute drug poisoning (discussion)].
    Ceska a slovenska psychiatrie, 1996, Volume: 92 Suppl 1

    Topics: Adult; Antipsychotic Agents; Central Nervous System Stimulants; Female; Humans; Male; Methylphenidat

1996
Analeptic use in clinical toxicology: a historical appraisal.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:2

    Topics: Barbiturates; Central Nervous System Stimulants; History, 20th Century; Humans; Methylphenidate; Poi

1997
Characterization of methylphenidate exposures reported to a regional poison control center.
    Archives of pediatrics & adolescent medicine, 2000, Volume: 154, Issue:12

    Topics: Adolescent; Adult; Age Distribution; Attention Deficit Disorder with Hyperactivity; Child; Child, Pr

2000
A profile of methylphenidate exposures.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Central Nervous System Stimulants; Child; Child, Preschool; Databases, Factual; F

2000
Letter: Treatment of acute barbiturate poisoning.
    American family physician, 1974, Volume: 10, Issue:3

    Topics: Barbiturates; Charcoal; Humans; Mannitol; Methylphenidate; Poisoning

1974
The continuing problem of barbiturate poisoning.
    American family physician, 1973, Volume: 8, Issue:2

    Topics: Accidents; Acidosis; Barbiturates; Diuresis; Drug Tolerance; Gastric Lavage; Humans; Mannitol; Methy

1973