methylphenidate has been researched along with Nervous System Disorders in 12 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Adverse events were mild to moderate in severity and similar to previous observations for this class of neurostimulants." | 2.74 | Efficacy and safety of dexmethylphenidate extended-release capsules administered once daily to children with attention-deficit/hyperactivity disorder. ( Childress, AC; Gerstner, O; Lopez, F; Muniz, R; Post, A; Spencer, T; Thulasiraman, A, 2009) |
| "Thirty patients with primary brain tumors underwent neuropsychologic assessment before and during treatment with methylphenidate." | 2.69 | Methylphenidate therapy improves cognition, mood, and function of brain tumor patients. ( Levin, VA; Meyers, CA; Valentine, AD; Weitzner, MA, 1998) |
| "Methylphenidate (Ritalin) is a commonly used central nervous stimulant." | 2.41 | Ritalin revisited: does it really help in neurological injury? ( Kajs-Wyllie, M, 2002) |
| "Neurobehavioural sequelae of traumatic brain injuries require an appropriate/effective pharmacological response in that they represent an important cause of disability." | 1.35 | Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury. ( Lombardi, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salehi, P | 1 |
| Shahmirzadi, ZY | 1 |
| Mirrezaei, FS | 1 |
| Shirvani Boushehri, F | 1 |
| Mayahi, F | 1 |
| Songhori, M | 1 |
| Abofazeli, M | 1 |
| Motaghinejad, M | 1 |
| Safari, S | 1 |
| Childress, AC | 1 |
| Spencer, T | 1 |
| Lopez, F | 1 |
| Gerstner, O | 1 |
| Thulasiraman, A | 1 |
| Muniz, R | 1 |
| Post, A | 1 |
| Kajs-Wyllie, M | 1 |
| Lombardi, F | 1 |
| von Kerékjártó, M | 1 |
| Bodner, RA | 1 |
| Lynch, T | 1 |
| Lewis, L | 1 |
| Kahn, D | 1 |
| Meyers, CA | 1 |
| Weitzner, MA | 1 |
| Valentine, AD | 1 |
| Levin, VA | 1 |
| Schain, RJ | 1 |
| Sackler, AM | 1 |
| Weltman, AS | 1 |
| Caine, ED | 1 |
| McBride, MC | 1 |
| Chiverton, P | 1 |
| Bamford, KA | 1 |
| Rediess, S | 1 |
| Shiao, J | 1 |
| Nutt, JG | 1 |
| Muenter, MD | 1 |
| Melton, LJ | 1 |
| Aronson, A | 1 |
| Kurland, LT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neurophysiological Studies of Focal and Generalized Forms of Dystonia Using Transcranial Magnetic Stimulation (TMS)[NCT00017875] | 120 participants | Observational | 2001-06-30 | Completed | |||
| The Study of Surround Inhibition in Patients With Dystonia[NCT00029601] | 60 participants | Observational | 2002-01-31 | Completed | |||
| Plasticity in Cervical Dystonia[NCT00323765] | 44 participants | Observational | 2006-05-05 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methylphenidate and Nervous System Disorders
| Article | Year |
|---|---|
Ritalin revisited: does it really help in neurological injury?
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Brain Neoplasms; Central Nervous Syst | 2002 |
Minimal brain Dysfunction.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child; Child, Prescho | 1975 |
3 trials available for methylphenidate and Nervous System Disorders
| Article | Year |
|---|---|
Efficacy and safety of dexmethylphenidate extended-release capsules administered once daily to children with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Capsules; Child; Delayed-Action Preparations; Dexmeth | 2009 |
[Differences between prophylactic and therapeutic effects of stimulant drugs].
Topics: Adult; Amphetamine; Antidepressive Agents; Humans; Male; Methylphenidate; Nervous System Diseases; P | 1966 |
Methylphenidate therapy improves cognition, mood, and function of brain tumor patients.
Topics: Adolescent; Adult; Affect; Aged; Brain; Brain Neoplasms; Central Nervous System Stimulants; Cognitio | 1998 |
7 other studies available for methylphenidate and Nervous System Disorders
| Article | Year |
|---|---|
A hypothetic role of minocycline as a neuroprotective agent against methylphenidate-induced neuronal mitochondrial dysfunction and tau protein hyper-phosphorylation: Possible role of PI3/Akt/GSK3β signaling pathway.
Topics: Anti-Bacterial Agents; Cognition; Glycogen Synthase Kinase 3 beta; Humans; Methylphenidate; Minocycl | 2019 |
[Clinical & psychotechnical study of a new medication for the neuroleptic syndrome].
Topics: Antipsychotic Agents; Autonomic Agents; Humans; Methylphenidate; Nervous System Diseases; Syndrome | 1958 |
Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury.
Topics: Amantadine; Animals; Antidepressive Agents; Antipsychotic Agents; Brain Injuries; Cognition; Cogniti | 2008 |
Serotonin syndrome.
Topics: Depressive Disorder; Humans; Isocarboxazid; Male; Methylphenidate; Middle Aged; Nervous System Disea | 1995 |
Effects of methylphenidate on whirler mice: an animal model for hyperkinesis.
Topics: Administration, Oral; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System | 1985 |
Tourette's syndrome in Monroe County school children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |
Epidemiology of dystonia in Rochester, Minnesota.
Topics: Blepharospasm; Dystonia; Humans; Methylphenidate; Minnesota; Nervous System Diseases; Torticollis | 1988 |