methylphenidate has been researched along with Necrosis in 4 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 36-year-old patient presented with a severe hand ischemia after intraarterial injection of four dissolved tablets of Methylphenidate each 10 mg (Ritalin into the right radial artery." | 3.72 | [Acute ischemia after intraarterial drug injection]. ( Aschwanden, M; Jäger, KA; Kliem, M; Stürchler, M; Thalhammer, C, 2004) |
| " Liver injury measured by either method was essentially nonexistent for dosages < or = 50 mg/kg in male mice, and was only minimally evident in female mice at the highest dosage testable." | 1.29 | Methylphenidate-induced hepatotoxicity in mice and its potentiation by beta-adrenergic agonist drugs. ( Harbison, RD; James, RC; Roberts, SM; Roth, L, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thalhammer, C | 1 |
| Aschwanden, M | 1 |
| Kliem, M | 1 |
| Stürchler, M | 1 |
| Jäger, KA | 1 |
| Gautschi, OP | 1 |
| Zellweger, R | 1 |
| Roberts, SM | 1 |
| Harbison, RD | 1 |
| Roth, L | 1 |
| James, RC | 1 |
| Crawford, SA | 1 |
| Evans, JA | 1 |
| Crawford, GE | 1 |
4 other studies available for methylphenidate and Necrosis
| Article | Year |
|---|---|
[Acute ischemia after intraarterial drug injection].
Topics: Acute Disease; Adult; Amputation, Surgical; Anti-Inflammatory Agents; Anticoagulants; Central Nervou | 2004 |
Necrotising myositis after intravenous methylphenidat (Ritalin) injection.
Topics: Adult; Central Nervous System Stimulants; Humans; Injections, Intravenous; Male; Methylphenidate; My | 2006 |
Methylphenidate-induced hepatotoxicity in mice and its potentiation by beta-adrenergic agonist drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alanine Transamina | 1994 |
Necrotizing fasciitis associated with Haemophilus aphrophilus. Report of a case.
Topics: Adult; Anti-Bacterial Agents; Drainage; Fascia; Haemophilus Infections; Humans; Inflammation; Male; | 1978 |