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methylphenidate and Muscle Spasticity

methylphenidate has been researched along with Muscle Spasticity in 4 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)

Research Excerpts

ExcerptRelevanceReference
"A 28-year-old woman with a long history of drug abuse experienced flaccid quadriplegia and bilateral loss of posterior column sensation a few minutes after an intravenous (IV) injection of methylphenidate hydrochloride."3.66Medial medullary syndrome in a drug abuser. ( Gonatas, NK; Lewis, RA; Mizutani, T, 1980)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CARTER, CH1
Dyer, JA1
Eisenberg, ES1
Mizutani, T1
Lewis, RA1
Gonatas, NK1
Boogerd, W1
Beijnen, JH1

Other Studies

4 other studies available for methylphenidate and Muscle Spasticity

ArticleYear
The effects of reserpine and methylphenidylacetate (ritalin) in mental defectives, spastics, and epileptics.
    Psychiatric research reports, 1956, Issue:4

    Topics: Antihypertensive Agents; Diet, Reducing; Epilepsy; Intellectual Disability; Methylphenidate; Muscle

1956
The ophthalmologist and narcolepsy, or why are so many ophthalmologists caught napping?
    Transactions of the American Ophthalmological Society, 1982, Volume: 80

    Topics: Adolescent; Adult; Aged; Blepharoptosis; Cataplexy; Child; Diplopia; Female; Hallucinations; Humans;

1982
Medial medullary syndrome in a drug abuser.
    Archives of neurology, 1980, Volume: 37, Issue:7

    Topics: Adult; Brain; Cerebral Infarction; Female; Humans; Injections, Intravenous; Intracranial Embolism an

1980
Methylphenidate for cerebral palsy with choreoathetosis.
    Annals of internal medicine, 2000, Mar-21, Volume: 132, Issue:6

    Topics: Adrenergic Agents; Cerebral Palsy; Chorea; Dystonia; Humans; Methylphenidate; Muscle Spasticity

2000