methylphenidate has been researched along with Muscle Contraction in 10 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Muscle fatigue is a disturbed homeostatic state characterized by a temporary inability to maintain force output and has lasting effects on the brain in the period immediately after exercise, such as decreased interhemispheric functional connectivity (FC)." | 2.87 | Methylphenidate alters brain connectivity after enhanced physical performance. ( Brooks, SJ; Ipser, J; King, M; Rauch, LH; Stein, DJ; van Breda, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| King, M | 1 |
| van Breda, K | 1 |
| Rauch, LH | 1 |
| Brooks, SJ | 1 |
| Stein, DJ | 1 |
| Ipser, J | 1 |
| Klass, M | 1 |
| Roelands, B | 1 |
| Lévénez, M | 1 |
| Fontenelle, V | 1 |
| Pattyn, N | 1 |
| Meeusen, R | 1 |
| Duchateau, J | 1 |
| Snider, RM | 1 |
| Ordway, GA | 1 |
| Gerald, MC | 1 |
| Soroko, FE | 1 |
| Mehta, NB | 1 |
| Maxwell, RA | 1 |
| Ferris, RM | 1 |
| Schroeder, DH | 1 |
| Braud, LW | 1 |
| Chinn, C | 1 |
| Weber, LJ | 1 |
| Ghouri, MS | 1 |
| Haley, TJ | 1 |
| Caldwell, RW | 1 |
| Goldberg, LI | 1 |
| Chernov, HI | 1 |
| Wilson, DE | 1 |
| Partyka, DA | 1 |
| Bernard, PS | 1 |
| Huebner, CF | 1 |
| Buckner, CK | 1 |
| Patil, PN | 1 |
| Tye, A | 1 |
| Malspeis, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of a Single Dose of Methylphenidate on Motor Performance[NCT04283604] | Phase 4 | 200 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for methylphenidate and Muscle Contraction
| Article | Year |
|---|---|
Methylphenidate alters brain connectivity after enhanced physical performance.
Topics: Adult; Brain; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2018 |
Effects of noradrenaline and dopamine on supraspinal fatigue in well-trained men.
Topics: Adrenergic alpha-Agonists; Adult; Athletic Performance; Bicycling; Dopamine; Dopamine Uptake Inhibit | 2012 |
8 other studies available for methylphenidate and Muscle Contraction
| Article | Year |
|---|---|
Effects of methylphenidate on rat endurance performance and neuromuscular transmission in vitro.
Topics: Acetylcholine; Animals; Behavior, Animal; Diaphragm; Electric Stimulation; Electrophysiology; In Vit | 1983 |
Bupropion hydrochloride ((+/-) alpha-t-butylamino-3-chloropropiophenone HCl): a novel antidepressant agent.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Cats; Dextroamphet | 1977 |
The effects of frontal EMG biofeedback and progressive relaxation upon hyperactivity and its behavioral concomitants.
Topics: Adolescent; Biofeedback, Psychology; Body Temperature; Child; Electromyography; Facial Muscles; Fema | 1978 |
The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat.
Topics: Alkynes; Animals; Atropine; Carbamates; Cats; Desipramine; Dimethylphenylpiperazinium Iodide; Electr | 1974 |
In vitro evaluation of a series of sympathomimetic amines and the beta-adrenergic blocking properties of cyclopentamine.
Topics: Animals; Cyclopentanes; Female; Ileum; In Vitro Techniques; Isoproterenol; Metaraminol; Methoxamine; | 1969 |
An evaluation of the vasodilation produced by mephentermine and certain other sympathomimetic amines.
Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Chemical Phenomena; Chemistry; Dextroamphetamine; | 1970 |
Pharmacological properties of Su-19789B, a unique central nervous system stimulant.
Topics: Adrenalectomy; Animals; Antidepressive Agents; Blood Pressure; Cats; Central Nervous System; Central | 1970 |
Steric aspects of adrenergic drugs. XII. Some peripheral effects of (+-)-erythro- and (+-)-threo-methylphenidate.
Topics: Animals; Cats; Chemical Phenomena; Chemistry; Cocaine; Dibenzylchlorethamine; Drug Synergism; Fluore | 1969 |