Page last updated: 2024-10-31

methylphenidate and Movement Disorders

methylphenidate has been researched along with Movement Disorders in 24 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."6.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"We report two case histories of previously healthy patients who both developed persistent dyskinetic syndromes (spasmodic torticollis and cranial dystonia, respectively) following the intake of norpseudoephedrine (NPE) as an appetite suppressant."3.69Dyskinesias possibly induced by norpseudoephedrine. ( Dressler, D; Thiel, A, 1994)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."2.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199019 (79.17)18.7374
1990's1 (4.17)18.2507
2000's2 (8.33)29.6817
2010's1 (4.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Stämpfli, D1
Weiler, S1
Burden, AM1
Marti, G1
Fattinger, K1
Zimmermann, H1
Exadaktylos, A1
Goldstein, LB1
DENZEL, HA1
ARRIGONI-MARTELLI, E2
BISIANI, M1
GENOVESE, E2
GOLDWURM, GF1
EISENBERG, L2
Mendhekar, DN1
Duggal, HS1
Martin, DM1
Thiel, A1
Dressler, D1
Extein, I1
Sleator, EK1
Costall, B1
Naylor, RJ1
Caine, ED1
McBride, MC1
Chiverton, P1
Bamford, KA1
Rediess, S1
Shiao, J1
Millichap, JG2
Boldrey, EE1
Betti, V1
Fann, WE2
Davis, JM1
Wilson, IC1
Wender, PH1
Palatucci, DM1
Fowler, GW1
Zaffiri, O1
Maritano, M1
Sainz, A1

Reviews

4 reviews available for methylphenidate and Movement Disorders

ArticleYear
Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance.
    European child & adolescent psychiatry, 2021, Volume: 30, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Combined Modality Therapy; Comorbidity; Conduct Disor

2021
Amphetamines and related drugs in motor recovery after stroke.
    Physical medicine and rehabilitation clinics of North America, 2003, Volume: 14, Issue:1 Suppl

    Topics: Central Nervous System Stimulants; Dextroamphetamine; Humans; Methylphenidate; Motor Cortex; Movemen

2003
Minimal brain dysfunction in children. Diagnosis and management.
    Pediatric clinics of North America, 1973, Volume: 20, Issue:1

    Topics: Abnormalities, Multiple; Affective Symptoms; Age Factors; Amphetamine; Attention; Attention Deficit

1973
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic

1967

Trials

3 trials available for methylphenidate and Movement Disorders

ArticleYear
Studies in hyperkinetic behavior. II. Laboratory and clinical evaluations of drug treatments.
    Neurology, 1967, Volume: 17, Issue:5

    Topics: Adolescent; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Child; Higher

1967
Methylphenidate in tardive dyskinesia.
    The American journal of psychiatry, 1973, Volume: 130, Issue:8

    Topics: Administration, Oral; Basal Ganglia Diseases; Clinical Trials as Topic; Evaluation Studies as Topic;

1973
Treatment of "minimal brain dysfunction" syndromes. Selection of drugs for children with hyperactivity and learning disabilities.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Amphetamine; Anticonvulsants; Brain Damage, Chronic; Child; Chlordiazepoxide; Chlorpromazine; Clinic

1967

Other Studies

18 other studies available for methylphenidate and Movement Disorders

ArticleYear
Orofacial dyskinesia induced by nasal Ritalin(R) (methylphenidate) sniffing: a rare case report from Switzerland.
    Human & experimental toxicology, 2013, Volume: 32, Issue:3

    Topics: Administration, Intranasal; Adult; Central Nervous System Stimulants; Humans; Hypnotics and Sedative

2013
Clinical trial of ritalin in the treatment of chronically underactive and depressed patients.
    Delaware medical journal, 1958, Volume: 30, Issue:8

    Topics: Depression; Electroencephalography; Methylphenidate; Movement Disorders

1958
[Effect of phenothiazine derivatives on increased motility of the mouse].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Nov-30, Volume: 34, Issue:22

    Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Chlorpromazine; Methylphenidate; Mice; Mov

1958
[Effects of iproniazid on increased spontaneous motility due to central stimulants].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Nov-30, Volume: 34, Issue:22

    Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Iproniazid; Methylphenidate; Movement

1958
DRUG THERAPY OF OVERACTIVITY IN CHILDREN (BRIEF SUMMARY OF REMARKS).
    Clinical proceedings - Children's Hospital of the District of Columbia, 1963, Volume: 19

    Topics: Child; Dextromoramide; Humans; Methylphenidate; Movement Disorders; Psychomotor Agitation; Psychopha

1963
Methylphenidate-induced rabbit syndrome.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:11

    Topics: Child; Dyskinesia, Drug-Induced; Humans; Male; Methylphenidate; Movement Disorders

2006
Hyperkinetic behavior disorders in children: clinical results with methylphenidate hydrochloride (Ritalin).
    Western medicine; the medical journal of the west, 1967, Volume: 8, Issue:1

    Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Male; Methylphenidate

1967
Dyskinesias possibly induced by norpseudoephedrine.
    Journal of neurology, 1994, Volume: 241, Issue:3

    Topics: Adult; Amphetamine; Appetite Depressants; Brain; Female; Humans; Magnetic Resonance Imaging; Methylp

1994
Methylphenidate-induced choreoathetosis.
    The American journal of psychiatry, 1978, Volume: 135, Issue:2

    Topics: Female; Haloperidol; Humans; Methapyrilene; Methylphenidate; Middle Aged; Movement Disorders; Physos

1978
Letter: Methylphenidate reaction.
    Pediatrics, 1975, Volume: 55, Issue:6

    Topics: Ataxia; Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Methylphenidate; Movemen

1975
Actions of dopaminergic agonists on motor function.
    Advances in neurology, 1975, Volume: 9

    Topics: Amantadine; Animals; Apomorphine; Behavior; Dextroamphetamine; Disease Models, Animal; Dopamine Anta

1975
Tourette's syndrome in Monroe County school children.
    Neurology, 1988, Volume: 38, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid

1988
[Specific correction of extrapyramidal disorders following neuroleptoanalgesia].
    Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica, 1966, Volume: 15, Issue:2

    Topics: Animals; Guinea Pigs; Humans; Methylphenidate; Mice; Morpholines; Movement Disorders; Myoclonus; Neu

1966
Iatrogenic dyskinesia. A unique reaction to parenteral methylphenidate.
    The Journal of nervous and mental disease, 1974, Volume: 159, Issue:1

    Topics: Adult; Humans; Iatrogenic Disease; Injections, Intravenous; Male; Methylphenidate; Movement Disorder

1974
[Apropos of neuroleptoanalgesia: the extrapyramidal symptomatology of neuroleptics and drugs that modify such symptoms].
    Acta anaesthesiologica, 1965, Volume: 16

    Topics: Anesthesia; Animals; Atropine; Humans; Methylphenidate; Monoamine Oxidase Inhibitors; Movement Disor

1965
Use of methylphenidate to counteract acute dystonic effects of phenothiazines.
    The American journal of psychiatry, 1966, Volume: 122, Issue:11

    Topics: Adult; Humans; Male; Methylphenidate; Movement Disorders; Perphenazine; Schizophrenia; Torticollis;

1966
Hyperkinetic disease of children: diagnosis and therapy.
    Diseases of the nervous system, 1966, Volume: 7 Suppl, Issue:7

    Topics: Adolescent; Adult; Aging; Brain Damage, Chronic; Child; Chlordiazepoxide; Dextroamphetamine; Humans;

1966
The management of the hyperkinetic child.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:5

    Topics: Child; Child, Preschool; Chlorpromazine; Dextroamphetamine; Diphenhydramine; Environment; Family; Hu

1966