methylphenidate has been researched along with Lung Neoplasms in 6 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Modafinil had no effect on cancer-related fatigue and should not be prescribed outside a clinical trial setting." | 9.19 | Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial. ( Bahadori, R; Bates, N; Benepal, T; Blackhall, F; Dutton, S; Fife, K; O'Brien, M; Spathis, A; Stone, P; Wee, B; Wharton, R, 2014) |
| "Modafinil had no effect on cancer-related fatigue and should not be prescribed outside a clinical trial setting." | 5.19 | Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial. ( Bahadori, R; Bates, N; Benepal, T; Blackhall, F; Dutton, S; Fife, K; O'Brien, M; Spathis, A; Stone, P; Wee, B; Wharton, R, 2014) |
| "Neurophysiologic measurements were made on a patient with multiple lung cancers and severe cancer-related fatigue (CRF) who responded to 5 mg methylphenidate twice daily, titrated to 10 mg twice daily after 2 weeks." | 3.74 | Combining objective and subjective outcomes in cancer-related fatigue: illustrations from a single case report. ( Davis, MP; Khoshknabi, DS; Kirkova, J; Ranganathan, VK; Siemionow, V; Walsh, D; Yue, GH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spathis, A | 1 |
| Fife, K | 1 |
| Blackhall, F | 1 |
| Dutton, S | 1 |
| Bahadori, R | 1 |
| Wharton, R | 1 |
| O'Brien, M | 1 |
| Stone, P | 1 |
| Benepal, T | 1 |
| Bates, N | 1 |
| Wee, B | 1 |
| Ruddy, KJ | 1 |
| Barton, D | 1 |
| Loprinzi, CL | 1 |
| Khoshknabi, DS | 1 |
| Davis, MP | 1 |
| Ranganathan, VK | 1 |
| Siemionow, V | 1 |
| Walsh, D | 1 |
| Kirkova, J | 1 |
| Yue, GH | 1 |
| Maréchal, R | 1 |
| Berghmans, T | 1 |
| Sculier, P | 1 |
| Giner-Sorolla, A | 1 |
| Greenbaum, J | 1 |
| Last-Barney, K | 1 |
| Anderson, LM | 1 |
| Budinger, JM | 1 |
| Williams, J | 1 |
| Wilhoite, S | 1 |
| Manos, P | 1 |
| Zollars, P | 1 |
| Youngberg, G | 1 |
| Dralle, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Modafinil for the Treatment of Fatigue in Lung Cancer: a Multicentre, Randomised, Double-blinded, Placebo-controlled Trial[NCT00829322] | Phase 4 | 208 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methylphenidate and Lung Neoplasms
| Article | Year |
|---|---|
Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial.
Topics: Aged; Aged, 80 and over; Benzhydryl Compounds; Carcinoma, Non-Small-Cell Lung; Central Nervous Syste | 2014 |
5 other studies available for methylphenidate and Lung Neoplasms
| Article | Year |
|---|---|
Laying to rest psychostimulants for cancer-related fatigue?
Topics: Benzhydryl Compounds; Carcinoma, Non-Small-Cell Lung; Central Nervous System Stimulants; Fatigue; Fe | 2014 |
Combining objective and subjective outcomes in cancer-related fatigue: illustrations from a single case report.
Topics: Central Nervous System Stimulants; Fatigue; Female; Humans; Lung Neoplasms; Methylphenidate; Middle | 2008 |
Successful treatment of intractable hiccup with methylphenidate in a lung cancer patient.
Topics: Carcinoma, Small Cell; Central Nervous System Stimulants; Hiccup; Humans; Lung Neoplasms; Male; Meth | 2003 |
Lack of carcinogenic effect of nitrosochlordiazepoxide and of nitrosomethylphenidate given orally to mice.
Topics: Animals; Carcinogens; Chlordiazepoxide; Female; Lung Neoplasms; Male; Methylphenidate; Mice; Neoplas | 1980 |
Pulmonary talc granulomatosis due to intravenous ritalin.
Topics: Adenocarcinoma; Adult; Granuloma; Humans; Injections, Intravenous; Lung Neoplasms; Male; Methylpheni | 1988 |