Page last updated: 2024-10-31

methylphenidate and Intellectual Disability

methylphenidate has been researched along with Intellectual Disability in 73 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"Optimal dosing of methylphenidate is practical and effective in some children with hyperkinetic disorder and intellectual disability."9.17Randomized controlled double-blind trial of optimal dose methylphenidate in children and adolescents with severe attention deficit hyperactivity disorder and intellectual disability. ( Baird, G; Bernard, S; Chadwick, O; Golaszewski, A; Jichi, F; Kelly, J; Kennedy, J; Liang, H; Riemer, K; Rodney, L; Sharma, K; Sharma, SP; Simonoff, E; Taylor, E; Walwyn, R; West, N; Whitwell, S; Wood, N, 2013)
"Methylphenidate is a first-line treatment for ADHD, however no previous meta-analysis has evaluated its overall efficacy for ADHD in children with comorbid intellectual disability (ID) or borderline intellectual functioning."6.61Therapeutic effects of methylphenidate for attention-deficit/hyperactivity disorder in children with borderline intellectual functioning or intellectual disability: A systematic review and meta-analysis. ( Carvalho, AF; Chen, TY; Chen, YW; Cheng, YS; Li, DJ; Lin, PY; Stubbs, B; Sun, CK; Tseng, PT; Wu, CK; Wu, MK, 2019)
"Optimal dosing of methylphenidate is practical and effective in some children with hyperkinetic disorder and intellectual disability."5.17Randomized controlled double-blind trial of optimal dose methylphenidate in children and adolescents with severe attention deficit hyperactivity disorder and intellectual disability. ( Baird, G; Bernard, S; Chadwick, O; Golaszewski, A; Jichi, F; Kelly, J; Kennedy, J; Liang, H; Riemer, K; Rodney, L; Sharma, K; Sharma, SP; Simonoff, E; Taylor, E; Walwyn, R; West, N; Whitwell, S; Wood, N, 2013)
"Antipsychotics, particularly risperidone, appear to be effective in reducing problem behaviors in children with intellectual disability."4.93Pharmacotherapy for mental health problems in people with intellectual disability. ( Findling, RL; Ji, NY, 2016)
"This randomized clinical trial of methylphenidate in children with intellectual disability (ID) by Simonoff et al."3.79Commentary: Filling out the evidence base for treatment of attention-deficit hyperactivity disorder symptoms in children with intellectual and developmental disability: conclusions for clinicians--a response to Simonoff et al. (2013). ( Eugene Arnold, L, 2013)
"The commentary by Arnold (2013) raises a number of interesting issues and speculations about the action of methylphenidate in children with intellectual disability (ID) and associated neurodevelopmental disorders, such as autism spectrum disorders."3.79Commentary: RCT of optimal dose methylphenidate in children and adolescents with severe ADHD and ID--a reply to Arnold (2013). ( Baird, G; Bernard, S; Simonoff, E; Taylor, E, 2013)
" Analysis of dose-response curves revealed significant linear components of trend on measures tapping sustained attention, visual selective attention, auditory selective attention, as well as two tasks tapping inhibition/impulsivity: delay of gratification and match-to-sample."2.71Treatment effects of methylphenidate on cognitive functioning in children with mental retardation and ADHD. ( Casat, CD; Cleveland, LA; Faria, LP; Jerger, SW; Lachar, D; Lane, DM; Loveland, KA; Payne, CD; Pearson, DA; Roache, JD; Santos, CW, 2004)
"The aim of this study was to investigate the effects of ongoing methylphenidate (MPH) on ADHD-related and autistic symptoms in Pervasive Developmental Disorders (PDD) in children who did not present any adverse effects to an initial acute dose administered at the clinic."2.71Methylphenidate for pervasive developmental disorders: safety and efficacy of acute single dose test and ongoing therapy: an open-pilot study. ( Cianchetti, C; Di Martino, A; Melis, G; Zuddas, A, 2004)
"Parents of children with mental retardation or borderline IQ who took part in two drug studies were surveyed by mail 4 weeks after their involvement."2.68Consumer satisfaction with involvement in drug research: a social validity study. ( Aman, MG; Wolford, PL, 1995)
"Fenfluramine dosage was gradually increased to a standardized dose of 1."2.67Fenfluramine and methylphenidate in children with mental retardation and attention deficit hyperactivity disorder: laboratory effects. ( Aman, MG; Arnold, LE; Kern, RA; McGhee, DE, 1993)
"The adverse side effects of methylphenidate were evaluated in 27 children with attention deficit hyperactivity disorder and IQs of 48 to 74 who participated in a double-blind study of two doses of methylphenidate and placebo."2.67Adverse side effects of methylphenidate among mentally retarded children with ADHD. ( Breaux, AM; Feldman, H; Gosling, A; Handen, BL; McAuliffe, S, 1991)
" Both groups were assessed for dyskinetic symptoms at ten weekly intervals as dosage was phased out in the neuroleptic group."2.66Dyskinetic symptoms in profoundly retarded residents following neuroleptic withdrawal and during methylphenidate treatment. ( Aman, MG; Singh, NN, 1985)
"Methylphenidate is a first-line treatment for ADHD, however no previous meta-analysis has evaluated its overall efficacy for ADHD in children with comorbid intellectual disability (ID) or borderline intellectual functioning."2.61Therapeutic effects of methylphenidate for attention-deficit/hyperactivity disorder in children with borderline intellectual functioning or intellectual disability: A systematic review and meta-analysis. ( Carvalho, AF; Chen, TY; Chen, YW; Cheng, YS; Li, DJ; Lin, PY; Stubbs, B; Sun, CK; Tseng, PT; Wu, CK; Wu, MK, 2019)
"Probably pseudohypoaldosteronism was a coincidental finding in this girl with a CDK13 mutation, but because only limited information is known about CDK13-related disorders, further investigation could be more informative to clarify this presentation."2.61One-month-old girl presenting with pseudohypoaldosteronism leading to the diagnosis of CDK13-related disorder: a case report and review of the literature. ( Ayman, A; Kremer, AK; van den Akker, M; Yakubov, R, 2019)
"Children and adolescents with autism spectrum disorders and intellectual disability have a high prevalence of attention-deficit/hyperactive disorder, mood disorders, catatonia and repetitive behaviours compared with children without autism."2.44Children with autism spectrum disorders and intellectual disability. ( McCarthy, J, 2007)
"Methylphenidate (2."1.91Complex Attention-Deficit/Hyperactivity Disorder in a Bilingual Child with Down Syndrome and Intellectual Disability. ( Carroll, G; Fogler, J; Froehlich, T; Moore, T; Nyp, SS; Soccorso, C, 2023)
"Although the relationship between attention-deficit/hyperactivity disorder (ADHD) and transport accidents has been shown, there is limited information on the relationship between medication and dose-response effects and transport accident risk."1.62Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH. ( Chen, VC; Chen, YL; Gossop, M; Liu, YC; Yang, YH, 2021)
"Methylphenidate was administered, for one week each, in a low dose of 0."1.26Methylphenidate in severely retarded residents and the clinical significance of stereotypic behavior. ( Aman, MG; Singh, NN, 1982)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199030 (41.10)18.7374
1990's15 (20.55)18.2507
2000's13 (17.81)29.6817
2010's11 (15.07)24.3611
2020's4 (5.48)2.80

Authors

AuthorsStudies
Moore, T1
Soccorso, C1
Fogler, J1
Carroll, G1
Froehlich, T1
Nyp, SS1
Sun, CK1
Tseng, PT1
Wu, CK1
Li, DJ1
Chen, TY1
Stubbs, B1
Carvalho, AF1
Chen, YW1
Lin, PY1
Cheng, YS1
Wu, MK1
Yakubov, R1
Ayman, A1
Kremer, AK1
van den Akker, M1
Miller, J1
Perera, B1
Shankar, R1
Joshi, G1
Wilens, T1
Firmin, ES1
Hoskova, B1
Biederman, J1
Liu, YC1
Chen, VC1
Yang, YH1
Chen, YL1
Gossop, M1
Operto, FF1
Mazza, R1
Campanozzi, S1
Pastorino, GM1
Amadori, E1
Coppola, G1
Tarrant, N1
Roy, M1
Deb, S1
Odedra, S1
Retzer, A1
Roy, A1
Eugene Arnold, L1
Simonoff, E2
Taylor, E2
Baird, G2
Bernard, S2
Lipkin, PH1
Ji, NY1
Findling, RL2
Deutsch, CK1
Dube, WV1
McIlvane, WJ1
Mace, FC2
Prager, KL1
Thomas, K1
Kochy, J1
Dyer, TJ1
Perry, L1
Pritchard, D1
Rowles, BM1
Peyre, H1
Delorme, R1
Chadwick, O1
Liang, H1
Whitwell, S1
Riemer, K1
Sharma, K1
Sharma, SP1
Wood, N1
Kelly, J1
Golaszewski, A1
Kennedy, J1
Rodney, L1
West, N1
Walwyn, R1
Jichi, F1
Pearson, DA3
Santos, CW3
Roache, JD3
Casat, CD3
Loveland, KA3
Lachar, D3
Lane, DM3
Faria, LP3
Cleveland, LA3
Aman, MG10
Buican, B1
Arnold, LE3
CARTER, CH2
MALEY, MC1
LEVY, JM1
JONES, BE1
CROLEY, HT1
BEAUJARD, M1
REVOL, E1
BUENO, UP1
CAPP, AB1
Jerger, SW2
Payne, CD2
Mansour, R1
Henderson, JA1
Di Martino, A1
Melis, G1
Cianchetti, C1
Zuddas, A1
Jou, R1
Handen, B1
Hardan, A1
Dicesare, A1
McAdam, DB1
Toner, A1
Varrell, J1
Correia Filho, AG1
Bodanese, R1
Silva, TL1
Alvares, JP1
Aman, M2
Rohde, LA1
Bilgiç, A1
Gürkan, K1
Türkoğlu, S1
McCarthy, J1
Poling, A1
Breuning, SE1
Varley, CK1
Trupin, EW1
Singh, NN3
Wolford, PL1
Johnson, CR1
Handen, BL6
Lubetsky, MJ1
Sacco, KA1
Janosky, J3
McAuliffe, S4
Breaux, AM4
Feldman, H4
Kern, RA3
McGhee, DE2
Blum, NJ1
Mauk, JE1
McComas, JJ1
Osborne, P1
Tumuluru, R1
Rojahn, J1
del Medico, V1
Detterman, DK1
Thompson, LA1
Searcy, E1
Corbett, JA1
Authier, J1
Donaldson, J1
Prica, G1
Alperin, E1
Ensz, G1
Morrison, TL1
Thomas, MD1
Renshaw, DC1
Schain, RJ1
Springer, NS1
Fricke, NL1
Gosling, A3
Voigt, RG1
Johnson, GH1
Brown, FR1
Marks, RE2
Turbott, SH2
Wilsher, CP2
Merry, SN2
Ploof, DL1
Payton, JB1
Burkhart, JE1
Hersen, M1
Helsel, WJ1
Knoll, E1
Millichamp, CJ1
McDaniel, KD1
St Jean, A1
Sterlin, C1
Noe, W1
Ban, TA1
Omenn, GS2
Alabiso, F1
Blacklidge, VY1
Ekblad, RL1
Browder, JA1
Davis, KV2
Millichap, JG1
Aymat, F1
Sturgis, LH1
Larsen, KW1
Egan, RA1
Sprague, RL1
Werry, JS1

Reviews

18 reviews available for methylphenidate and Intellectual Disability

ArticleYear
Therapeutic effects of methylphenidate for attention-deficit/hyperactivity disorder in children with borderline intellectual functioning or intellectual disability: A systematic review and meta-analysis.
    Scientific reports, 2019, 11-04, Volume: 9, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Int

2019
One-month-old girl presenting with pseudohypoaldosteronism leading to the diagnosis of CDK13-related disorder: a case report and review of the literature.
    Journal of medical case reports, 2019, Dec-29, Volume: 13, Issue:1

    Topics: CDC2 Protein Kinase; Chelating Agents; DNA Mutational Analysis; Female; Humans; Infant; Intellectual

2019
Clinical guidance on pharmacotherapy for the treatment of attention-deficit hyperactivity disorder (ADHD) for people with intellectual disability.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:15

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Child; Clonidi

2020
Pharmacotherapy of attention deficit/hyperactivity disorder in individuals with autism spectrum disorder: A systematic review of the literature.
    Journal of psychopharmacology (Oxford, England), 2021, Volume: 35, Issue:3

    Topics: Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder;

2021
The effectiveness of methylphenidate in the management of Attention Deficit Hyperactivity Disorder (ADHD) in people with intellectual disabilities: A systematic review.
    Research in developmental disabilities, 2018, Volume: 83

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Int

2018
Pharmacotherapy for mental health problems in people with intellectual disability.
    Current opinion in psychiatry, 2016, Volume: 29, Issue:2

    Topics: Aggression; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Ce

2016
Attention deficits, Attention-Deficit Hyperactivity Disorder, and intellectual disabilities.
    Developmental disabilities research reviews, 2008, Volume: 14, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Chro

2008
Review of pharmacotherapy options for the treatment of attention-deficit/hyperactivity disorder (ADHD) and ADHD-like symptoms in children and adolescents with developmental disorders.
    Developmental disabilities research reviews, 2010, Volume: 16, Issue:3

    Topics: Adolescent; Amphetamines; Antipsychotic Agents; Atomoxetine Hydrochloride; Attention Deficit Disorde

2010
Children with autism spectrum disorders and intellectual disability.
    Current opinion in psychiatry, 2007, Volume: 20, Issue:5

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with

2007
Stimulant drug effects in developmental disorders and hyperactivity--toward a resolution of disparate findings.
    Journal of autism and developmental disorders, 1982, Volume: 12, Issue:4

    Topics: Amphetamines; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Autistic Disorder;

1982
What is so special about special education?
    The American psychologist, 1997, Volume: 52, Issue:10

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Combined Modalit

1997
Helping the patient who has pervasive developmental disorder.
    JAAPA : official journal of the American Academy of Physician Assistants, 2001, Volume: 14, Issue:10

    Topics: Child; Child Development Disorders, Pervasive; Communication; Diagnosis, Differential; Haloperidol;

2001
Behavioural and drug treatment of children with severe mental handicap.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: Spec No 9

    Topics: Amphetamines; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bar

1975
Minimal brain Dysfunction.
    Current problems in pediatrics, 1975, Volume: 5, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child; Child, Prescho

1975
Nutrition and drug therapy for persons with developmental disabilities.
    American journal of mental deficiency, 1975, Volume: 80, Issue:3

    Topics: Anticonvulsants; Antidepressive Agents; Appetite; Dextroamphetamine; Drug-Related Side Effects and A

1975
Pharmacological treatment of self-injurious behavior in mentally retarded persons.
    Journal of autism and developmental disorders, 1985, Volume: 15, Issue:3

    Topics: Adolescent; Anti-Anxiety Agents; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Double-Blind

1985
Genetic approaches to the syndrome of minimal brain dysfunction.
    Annals of the New York Academy of Sciences, 1973, Feb-28, Volume: 205

    Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Diseases in Tw

1973
Genetic issues in the syndrome of minimal brain dysfunction.
    Seminars in psychiatry, 1973, Volume: 5, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Dextroamphetamine; Diseases in Twins; Female; Humans;

1973

Trials

28 trials available for methylphenidate and Intellectual Disability

ArticleYear
Randomized controlled double-blind trial of optimal dose methylphenidate in children and adolescents with severe attention deficit hyperactivity disorder and intellectual disability.
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2013
Treatment effects of methylphenidate on behavioral adjustment in children with mental retardation and ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Cross-Over

2003
Methylphenidate treatment in children with borderline IQ and mental retardation: analysis of three aggregated studies.
    Journal of child and adolescent psychopharmacology, 2003,Spring, Volume: 13, Issue:1

    Topics: Adolescent; Adolescent Behavior; Attention Deficit Disorder with Hyperactivity; Central Nervous Syst

2003
Treatment effects of methylphenidate on cognitive functioning in children with mental retardation and ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:6

    Topics: Analysis of Variance; Attention; Attention Deficit Disorder with Hyperactivity; Central Nervous Syst

2004
Effects of methylphenidate treatment in children with mental retardation and ADHD: individual variation in medication response.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Behavior; Central Nervous System Stimulants; Child; C

2004
Methylphenidate for pervasive developmental disorders: safety and efficacy of acute single dose test and ongoing therapy: an open-pilot study.
    Journal of child and adolescent psychopharmacology, 2004,Summer, Volume: 14, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Central Nervous System

2004
The effects of methylphenidate on a functional analysis of disruptive behavior: a replication and extension.
    Journal of applied behavior analysis, 2005,Spring, Volume: 38, Issue:1

    Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Behavior; Behavior Therapy; Central

2005
Comparison of risperidone and methylphenidate for reducing ADHD symptoms in children and adolescents with moderate mental retardation.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:8

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2005
Double-blind administration of methylphenidate to mentally retarded children with attention deficit disorder; a preliminary study.
    American journal of mental deficiency, 1982, Volume: 86, Issue:6

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior; Child, Preschool;

1982
Consumer satisfaction with involvement in drug research: a social validity study.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:7

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clinical Trials

1995
Efficacy of methylphenidate and behavioral intervention on classroom behavior in children with ADHD and mental retardation.
    Behavior modification, 1994, Volume: 18, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Child, Preschool

1994
Prediction of response to methylphenidate among children with ADHD and mental retardation.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1994, Volume: 33, Issue:8

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Double-Blind

1994
Fenfluramine and methylphenidate in children with mental retardation and attention deficit hyperactivity disorder: laboratory effects.
    Journal of autism and developmental disorders, 1993, Volume: 23, Issue:3

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Cogni

1993
Separate and combined effects of methylphenidate and a behavioral intervention on disruptive behavior in children with mental retardation.
    Journal of applied behavior analysis, 1996,Fall, Volume: 29, Issue:3

    Topics: Aggression; Attention; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Child

1996
Fenfluramine and methylphenidate in children with mental retardation and borderline IQ: clinical effects.
    American journal of mental retardation : AJMR, 1997, Volume: 101, Issue:5

    Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

1997
Long-term follow-up of children with mental retardation/borderline intellectual functioning and ADHD.
    Journal of abnormal child psychology, 1997, Volume: 25, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

1997
Effects and noneffects of methylphenidate in children with mental retardation and ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1992, Volume: 31, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Double-Blind

1992
Methylphenidate and thioridazine in the treatment of intellectually subaverage children: effects on cognitive-motor performance.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:5

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Doubl

1991
Adverse side effects of methylphenidate among mentally retarded children with ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:2

    Topics: Anxiety; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior; Double-Blind Method;

1991
Clinical effects of methylphenidate and thioridazine in intellectually subaverage children.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:2

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorder

1991
Fenfluramine and mental retardation.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Double-Blind Method; Encopresis; Enuresis; Fenflurami

1991
Efficacy of methylphenidate among mentally retarded children with attention deficit hyperactivity disorder.
    Pediatrics, 1990, Volume: 86, Issue:6

    Topics: Analysis of Variance; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child Behavio

1990
Treatment of ADDH in mentally retarded children: a preliminary study.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1989, Volume: 28, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Clinical Trials as Topic; Co

1989
Dyskinetic symptoms in profoundly retarded residents following neuroleptic withdrawal and during methylphenidate treatment.
    Journal of mental deficiency research, 1985, Volume: 29 ( Pt 2)

    Topics: Adolescent; Adult; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Dyskinesia,

1985
Clinical studies with propericiazine (R.P. 8909).
    Diseases of the nervous system, 1967, Volume: 28, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Association; Behavior; Chlorpromazine; Chronic Disease; Clin

1967
The effectiveness of methylphenidate hydrochloride (ritalin) on learning and behavior in public school educable mentally retarded children.
    Pediatrics, 1971, Volume: 47, Issue:5

    Topics: Adolescent; Child; Child Behavior; Clinical Trials as Topic; Education of Intellectually Disabled; E

1971
Hyperkinetic behavior and learning disorders. 3. Battery of neuropsychological tests in controlled trial of methylphenidate.
    American journal of diseases of children (1960), 1968, Volume: 116, Issue:3

    Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Female; Humans; Hydrochloric Acid; In

1968
Stereotyped behavior and activity level in severe retardates: the effect of drugs.
    American journal of mental deficiency, 1969, Volume: 73, Issue:5

    Topics: Adolescent; Analysis of Variance; Arousal; Humans; Intellectual Disability; Male; Methylphenidate; M

1969

Other Studies

27 other studies available for methylphenidate and Intellectual Disability

ArticleYear
Complex Attention-Deficit/Hyperactivity Disorder in a Bilingual Child with Down Syndrome and Intellectual Disability.
    Journal of developmental and behavioral pediatrics : JDBP, 2023, 09-01, Volume: 44, Issue:7

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cesarean Section; Child; Down Syndrome; Female

2023
Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH.
    Epidemiology and psychiatric sciences, 2021, Feb-15, Volume: 30

    Topics: Accidents, Traffic; Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Defic

2021
Attention deficit hyperactivity disorder in genetically-determined intellectual disability.
    Minerva pediatrica, 2019, Volume: 71, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Follow-Up S

2019
Commentary: Filling out the evidence base for treatment of attention-deficit hyperactivity disorder symptoms in children with intellectual and developmental disability: conclusions for clinicians--a response to Simonoff et al. (2013).
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Female; Humans; In

2013
Commentary: RCT of optimal dose methylphenidate in children and adolescents with severe ADHD and ID--a reply to Arnold (2013).
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Female; Humans; In

2013
Methylphenidate reduces ADHD symptoms in children with severe ADHD and intellectual disability.
    Evidence-based mental health, 2013, Volume: 16, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Female; Humans; In

2013
Effects of stimulant medication under varied motivational operations.
    Journal of applied behavior analysis, 2009,Spring, Volume: 42, Issue:1

    Topics: Attention; Attention Deficit Disorder with Hyperactivity; Choice Behavior; Delayed-Action Preparatio

2009
A case of severe hyperthermia after administration of methylphenidate.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Central Nervous System Stimulants; Child; Fever; Humans; Intellectual Disability; Male; Methylphenid

2012
The effects of reserpine and methylphenidylacetate (ritalin) in mental defectives, spastics, and epileptics.
    Psychiatric research reports, 1956, Issue:4

    Topics: Antihypertensive Agents; Diet, Reducing; Epilepsy; Intellectual Disability; Methylphenidate; Muscle

1956
Parenteral use of methylphenidate (ritalin).
    Diseases of the nervous system, 1957, Volume: 18, Issue:4

    Topics: Brain; Brain Injuries; Diet, Reducing; Epilepsy; Humans; Intellectual Disability; Methylphenidate

1957
Effects of methylphenidate (ritalin) on drug-induced drowsiness in mentally retarded patients.
    American journal of mental deficiency, 1957, Volume: 62, Issue:2

    Topics: Humans; Intellectual Disability; Methylphenidate; Persons with Mental Disabilities; Sleep; Sleep Sta

1957
[Clinical tests of the activity of RP 8228 (phacetoperane) in an oligophrenic child].
    Pediatrie, 1960, Volume: 15

    Topics: Child; Diet, Reducing; Humans; Intellectual Disability; Methylphenidate; Piperidines

1960
[Clinical results following the use of a new psychotonic in mentally defective children and mentally defective epileptics].
    Hospital (Rio de Janeiro, Brazil), 1962, Volume: 62

    Topics: Child; Epilepsy; Humans; Intellectual Disability; Methylphenidate

1962
Psychostimulant treatment of adults with mental retardation and attention-deficit hyperactivity disorder.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2004, Volume: 12, Issue:4

    Topics: Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants

2004
Excessive masturbation and hypersexual behavior associated with methylphenidate.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2007, Volume: 46, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dopamine Up

2007
Effects of methylphenidate on the fixed-ratio performance of mentally retarded children.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:4

    Topics: Adolescent; Child; Conditioning, Operant; Female; Humans; Intellectual Disability; Male; Methylpheni

1983
Methylphenidate in severely retarded residents and the clinical significance of stereotypic behavior.
    Applied research in mental retardation, 1982, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Attention; Behavior; Double-Blind Method; Eating; Female; Humans; Intellectual Di

1982
Family practice grand rounds. Hyperactivity: a symptom, not a disease entity.
    The Journal of family practice, 1977, Volume: 4, Issue:5

    Topics: Anxiety; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Epilepsy, Absence;

1977
Judgments of educators and child-care personnel about appropriate treatment for mentally retarded or normal, overactive or withdrawn, boys.
    Journal of clinical psychology, 1976, Volume: 32, Issue:2

    Topics: Allied Health Personnel; Attitude of Health Personnel; Behavior Therapy; Child; Child Behavior Disor

1976
Mentally retarded, hyperkinetic and psychotic.
    Diseases of the nervous system, 1977, Volume: 38, Issue:7

    Topics: Adult; Female; Humans; Hyperkinesis; Indoles; Intellectual Disability; Methylphenidate; Molindone; P

1977
Mental retardation and ADHD!
    Pediatrics, 1992, Volume: 89, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Intellectual Disability; Methylphenida

1992
Attention disorder in children: is the literature purged? Was it ever tainted?
    JAMA, 1989, Apr-28, Volume: 261, Issue:16

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Crime; Fraud; Humans; Intellectual Disa

1989
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 2).
    Clinical pediatrics, 1986, Volume: 25, Issue:3

    Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Child; Chlorpromazine; Haloper

1986
The use of methylphenidate in autism.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1988, Volume: 27, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Humans; Intellectual Disabi

1988
Inhibitory functions of attention in reducing hyperactive behavior.
    American journal of mental deficiency, 1972, Volume: 77, Issue:3

    Topics: Attention; Behavior Therapy; Brain; Child; Child, Preschool; Conditioning, Operant; Education of Int

1972
Appropriate use of psychic drugs in school children.
    American journal of diseases of children (1960), 1972, Volume: 124, Issue:4

    Topics: Adolescent; Antidepressive Agents; Child; Child Behavior Disorders; Humans; Intellectual Disability;

1972
The effect of drugs on stereotyped and nonstereotyped operant behaviors in retardates.
    Psychopharmacologia, 1971, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Behavior; Conditioning, Operant; Hospitalization; Humans; Intellectual Disability

1971