Page last updated: 2024-10-31

methylphenidate and Infertility

methylphenidate has been researched along with Infertility in 2 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Infertility: A reduced or absent capacity to reproduce.

Research Excerpts

ExcerptRelevanceReference
" Long-term use of MPH has been associated not only with an increase in the development of neurodegenerative diseases, but it also causes side effects on male fertility in experimental animals."1.72Increased sperm deoxyribonucleic acid damage leads to poor embryo quality and subfertility of male rats treated with methylphenidate hydrochloride in adolescence. ( Bellin, CS; da Costa Nunes Gomes, AC; da Silva Dias, S; de Araújo, MP; de Queiroz de Rosa, T; Mendes, TB; Miraglia, SM; Vendramini, V, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
da Costa Nunes Gomes, AC1
Bellin, CS1
da Silva Dias, S1
de Queiroz de Rosa, T1
de Araújo, MP1
Miraglia, SM1
Mendes, TB1
Vendramini, V1
Golub, M1
Costa, L1
Crofton, K1
Frank, D1
Fried, P1
Gladen, B1
Henderson, R1
Liebelt, E1
Lusskin, S1
Marty, S1
Rowland, A1
Scialli, J1
Vore, M1

Reviews

1 review available for methylphenidate and Infertility

ArticleYear
NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of methylphenidate.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2005, Volume: 74, Issue:4

    Topics: Animals; Central Nervous System Stimulants; Developmental Disabilities; Female; Humans; Infant, Newb

2005

Other Studies

1 other study available for methylphenidate and Infertility

ArticleYear
Increased sperm deoxyribonucleic acid damage leads to poor embryo quality and subfertility of male rats treated with methylphenidate hydrochloride in adolescence.
    Andrology, 2022, Volume: 10, Issue:8

    Topics: Animals; Central Nervous System Stimulants; Chromatin; Female; Infertility; Male; Methylphenidate; P

2022