Page last updated: 2024-10-31

methylphenidate and Heroin Abuse

methylphenidate has been researched along with Heroin Abuse in 10 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" The goal of the present study was to investigate these parameters of striatal dopamine transmission in heroin dependence and their association with drug seeking behavior."9.16Deficits in dopamine D(2) receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types of addiction. ( Broft, A; Comer, SD; Cook, S; Grassetti, A; Liu, F; Martinez, D; Orlowska, D; Saccone, PA; Slifstein, M; Van Heertum, R, 2012)
" The goal of the present study was to investigate these parameters of striatal dopamine transmission in heroin dependence and their association with drug seeking behavior."5.16Deficits in dopamine D(2) receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types of addiction. ( Broft, A; Comer, SD; Cook, S; Grassetti, A; Liu, F; Martinez, D; Orlowska, D; Saccone, PA; Slifstein, M; Van Heertum, R, 2012)
"Methylphenidate was well tolerated with similar retention rates compared with the placebo."2.78A randomized, controlled, pilot trial of methylphenidate and cognitive-behavioral group therapy for cocaine dependence in heroin prescription. ( Boss, J; Bürki, C; Dürsteler-MacFarland, KM; Farronato, NS; Kuntze, MF; Petitjean, SA; Strasser, J; Wiesbeck, GA, 2013)
" At each daily visit, signs and symptoms were assessed, and medications and dosing instructions were given for the following 24 hours."1.37A nonopioid procedure for outpatient opioid detoxification. ( Baier, AR; Coons, EE; Fingesten, A; Ockert, DM; Volpicelli, JR, 2011)
"Thirty adolescents with histories of minimal brain dysfunction who had been treated for at least six months with chemotherapy were compared with 30 adolescents who had not been so treated."1.25Childhood chemotherapy and later drug abuse and growth curve: a follow-up study of 30 adolescents. ( Beck, L; Langford, WS; Mackay, M; Sum, G, 1975)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, LY1
Crum, RM1
Strain, EC1
Martins, SS1
Mojtabai, R1
Dahlman, D1
Håkansson, A1
Björkman, P1
Blomé, MA1
Kral, AH1
Ockert, DM1
Volpicelli, JR1
Baier, AR1
Coons, EE1
Fingesten, A1
Martinez, D1
Saccone, PA1
Liu, F1
Slifstein, M1
Orlowska, D1
Grassetti, A1
Cook, S1
Broft, A1
Van Heertum, R1
Comer, SD1
Dürsteler-MacFarland, KM1
Farronato, NS1
Strasser, J1
Boss, J1
Kuntze, MF1
Petitjean, SA1
Bürki, C1
Wiesbeck, GA1
Smith, TA1
Kronick, RF1
Arnett, EN1
Battle, WE1
Russo, JV1
Roberts, WC1
Raskind, M1
Bradford, T1
Beck, L1
Langford, WS1
Mackay, M1
Sum, G1
Idanpaan-Heikkila, J1

Trials

2 trials available for methylphenidate and Heroin Abuse

ArticleYear
Deficits in dopamine D(2) receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types of addiction.
    Biological psychiatry, 2012, Feb-01, Volume: 71, Issue:3

    Topics: Adult; Behavior, Addictive; Choice Behavior; Corpus Striatum; Dopamine; Female; Heroin; Heroin Depen

2012
A randomized, controlled, pilot trial of methylphenidate and cognitive-behavioral group therapy for cocaine dependence in heroin prescription.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1

    Topics: Adult; Analgesics, Opioid; Central Nervous System Stimulants; Chi-Square Distribution; Cocaine-Relat

2013

Other Studies

8 other studies available for methylphenidate and Heroin Abuse

ArticleYear
Patterns of concurrent substance use among adolescent nonmedical ADHD stimulant users.
    Addictive behaviors, 2015, Volume: 49

    Topics: Adolescent; Amphetamines; Analgesics, Opioid; Central Nervous System Stimulants; Child; Cocaine-Rela

2015
Correlates of Skin and Soft Tissue Infections in Injection Drug Users in a Syringe-Exchange Program in Malmö, Sweden.
    Substance use & misuse, 2015, Volume: 50, Issue:12

    Topics: Adult; Amphetamine-Related Disorders; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Drug

2015
A nonopioid procedure for outpatient opioid detoxification.
    Journal of addiction medicine, 2011, Volume: 5, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Benzhydryl Compounds; Central Nervous Syste

2011
The policy culture of drugs: Ritalin, methadone, and the control of deviant behavior.
    The International journal of the addictions, 1979, Volume: 14, Issue:7

    Topics: Child; Heroin Dependence; Humans; Hyperkinesis; Methadone; Methylphenidate; Politics; Public Policy;

1979
Intravenous injection of talc-containing drugs intended for oral use. A cause of pulmonary granulomatosis and pulmonary hypertension.
    The American journal of medicine, 1976, May-10, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Dyspnea; Female; Granuloma; Heroin Dependence; Humans; Hypertension, Pulmonary; I

1976
Methylphenidate (ritalin) abuse and methadone maintenance.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Adult; Amphetamine; Atropa belladonna; Barbiturates; Diazepam; Female; Heroin Dependence; Humans; Ma

1975
Childhood chemotherapy and later drug abuse and growth curve: a follow-up study of 30 adolescents.
    The American journal of psychiatry, 1975, Volume: 132, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Body Height; Cannabis; Child; Child Behav

1975
Patterns, range and effects of misused psychotropic substances in Europe.
    The Medical journal of Australia, 1973, Sep-01, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Age Factors; Amphetamine; Analgesics; Cannabis; Drug and Narcotic Control; Europe

1973