methylphenidate has been researched along with HIV Coinfection in 9 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of 2 psychostimulant medications, methylphenidate hydrochloride (Ritalin) and pemoline (Cylert), with a placebo intervention for the treatment of fatigue in patients with HIV disease." | 5.09 | A randomized, double-blind, placebo-controlled trial of psychostimulants for the treatment of fatigue in ambulatory patients with human immunodeficiency virus disease. ( Breitbart, W; Funesti-Esch, J; Kaim, M; Rosenfeld, B, 2001) |
| "Four months after initiation of methylphenidate therapy the increased daytime sleepiness improved and excessive weight gain stopped." | 3.88 | Case report: narcolepsy type 1 in an adolescent with HIV infection-coincidence or potential trigger? ( Berger, C; Hackenberg, A; Paioni, P; Relly, C; Scherrer, KS, 2018) |
| "Methylphenidate is a psychostimulant originally used for the treatment of attention-deficit disorder." | 2.48 | Methylphenidate: established and expanding roles in symptom management. ( Prommer, E, 2012) |
| "Treatment with methylphenidate has been advocated in patients with traumatic brain injury and stroke, cancer patients, and those with human immunodeficiency virus infection." | 2.41 | Methylphenidate: its pharmacology and uses. ( Challman, TD; Lipsky, JJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McLaurin, KA | 1 |
| Li, H | 1 |
| Booze, RM | 1 |
| Fairchild, AJ | 1 |
| Mactutus, CF | 1 |
| Scherrer, KS | 1 |
| Relly, C | 1 |
| Hackenberg, A | 1 |
| Berger, C | 1 |
| Paioni, P | 1 |
| Prommer, E | 1 |
| Volkow, ND | 1 |
| Wang, GJ | 1 |
| Fowler, JS | 1 |
| Telang, F | 1 |
| Jayne, M | 1 |
| Wong, C | 1 |
| Hennink, M | 1 |
| Abbas, Z | 1 |
| Choudhri, Y | 1 |
| Diener, T | 1 |
| Lloyd, K | 1 |
| Archibald, CP | 1 |
| Cule, S | 1 |
| van Dyck, CH | 1 |
| McMahon, TJ | 1 |
| Rosen, MI | 1 |
| O'Malley, SS | 1 |
| O'Connor, PG | 1 |
| Lin, CH | 1 |
| Pearsall, HR | 1 |
| Woods, SW | 1 |
| Kosten, TR | 1 |
| Challman, TD | 1 |
| Lipsky, JJ | 1 |
| Breitbart, W | 1 |
| Rosenfeld, B | 1 |
| Kaim, M | 1 |
| Funesti-Esch, J | 1 |
| Swenson, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methylphenidate Effect on Performing Humphrey Visual Fields[NCT02162381] | 32 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| A Parallel-group, Double-blind, Placebo-controlled Study of Methylphenidate as an Add on Therapy for Mirtazapine in the Treatment of Major Depressive Disorder in Cancer Patients Under Palliative Care[NCT01497548] | Phase 3 | 120 participants (Anticipated) | Interventional | 2011-03-31 | Recruiting | ||
| Fatigue in Sarcoidosis - A Feasibility Study Investigating the Treatment of Fatigue in Stable Sarcoidosis Patients Using Methylphenidate[NCT02643732] | 30 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methylphenidate and HIV Coinfection
| Article | Year |
|---|---|
Methylphenidate: established and expanding roles in symptom management.
Topics: Analgesics, Opioid; Brain Neoplasms; Central Nervous System Stimulants; Cognition; Cognition Disorde | 2012 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
Methylphenidate: its pharmacology and uses.
Topics: Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System Stimulants; De | 2000 |
3 trials available for methylphenidate and HIV Coinfection
| Article | Year |
|---|---|
Stimulant-induced enhanced sexual desire as a potential contributing factor in HIV transmission.
Topics: Administration, Oral; Adult; Central Nervous System Stimulants; Cocaine-Related Disorders; Comorbidi | 2007 |
Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study.
Topics: Adult; Attention; Central Nervous System Stimulants; Cognition Disorders; Delayed-Action Preparation | 1997 |
A randomized, double-blind, placebo-controlled trial of psychostimulants for the treatment of fatigue in ambulatory patients with human immunodeficiency virus disease.
Topics: Ambulatory Care; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Female; HIV Infect | 2001 |
4 other studies available for methylphenidate and HIV Coinfection
| Article | Year |
|---|---|
Unraveling Individual Differences In The HIV-1 Transgenic Rat: Therapeutic Efficacy Of Methylphenidate.
Topics: Animals; Behavior, Animal; Biological Variation, Population; Central Nervous System Stimulants; Cogn | 2018 |
Case report: narcolepsy type 1 in an adolescent with HIV infection-coincidence or potential trigger?
Topics: Adolescent; Central Nervous System Stimulants; Drug Monitoring; HIV Infections; Humans; Male; Methyl | 2018 |
Risk behaviours for infection with HIV and hepatitis C virus among people who inject drugs in Regina, Saskatchewan.
Topics: Adult; Chlamydia Infections; Cocaine-Related Disorders; Condoms; Cross-Sectional Studies; Female; Go | 2007 |
What are the pharmacologic considerations when treating depression in patients with HIV infection?
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Comorbidity; Depressive Disorder; H | 1998 |