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methylphenidate and Glioma

methylphenidate has been researched along with Glioma in 4 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with primary brain tumors underwent neuropsychologic assessment before and during treatment with methylphenidate."2.69Methylphenidate therapy improves cognition, mood, and function of brain tumor patients. ( Levin, VA; Meyers, CA; Valentine, AD; Weitzner, MA, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gehring, K1
Patwardhan, SY1
Collins, R1
Groves, MD1
Etzel, CJ1
Meyers, CA3
Wefel, JS1
Mulhern, RK1
Merchant, TE1
Gajjar, A1
Reddick, WE1
Kun, LE1
Weitzner, MA2
Valentine, AD1
Levin, VA1

Reviews

2 reviews available for methylphenidate and Glioma

ArticleYear
Late neurocognitive sequelae in survivors of brain tumours in childhood.
    The Lancet. Oncology, 2004, Volume: 5, Issue:7

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Central Nervous System Stimulants; Child; Child, Pres

2004
Cognitive functioning and quality of life in malignant glioma patients: a review of the literature.
    Psycho-oncology, 1997, Volume: 6, Issue:3

    Topics: Adult; Brain Neoplasms; Central Nervous System Stimulants; Chemotherapy, Adjuvant; Clinical Trials a

1997

Trials

2 trials available for methylphenidate and Glioma

ArticleYear
A randomized trial on the efficacy of methylphenidate and modafinil for improving cognitive functioning and symptoms in patients with a primary brain tumor.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Adult; Benzhydryl Compounds; Brain Neoplasms; Central Nervous System Stimulants; Cognition Disorders

2012
Methylphenidate therapy improves cognition, mood, and function of brain tumor patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Affect; Aged; Brain; Brain Neoplasms; Central Nervous System Stimulants; Cognitio

1998