methylphenidate has been researched along with Gambling, Pathologic in 3 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate was effective in 'normalizing' the decision-making behavior of patients, such that they became less risk taking on medication, although there were no significant effects on other aspects of cognitive function, including working memory, attentional set shifting, and reversal learning." | 6.72 | Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia. ( Clark, L; Hodges, JR; Mehta, MA; Nestor, PJ; Rahman, S; Robbins, TW; Sahakian, BJ, 2006) |
| " In a randomized placebo-controlled study in healthy volunteers, we show that methylphenidate, a drug that increases tonic dopamine levels, systematically reduced striatal phasic BOLD responses to gain and loss in a gambling task as measured with fMRI." | 5.24 | High reward expectancy during methylphenidate depresses the dopaminergic response to gain and loss. ( Evers, EA; Ramaekers, JG; Stiers, P, 2017) |
| "Methylphenidate was effective in 'normalizing' the decision-making behavior of patients, such that they became less risk taking on medication, although there were no significant effects on other aspects of cognitive function, including working memory, attentional set shifting, and reversal learning." | 2.72 | Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia. ( Clark, L; Hodges, JR; Mehta, MA; Nestor, PJ; Rahman, S; Robbins, TW; Sahakian, BJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evers, EA | 1 |
| Stiers, P | 1 |
| Ramaekers, JG | 1 |
| Rahman, S | 1 |
| Robbins, TW | 1 |
| Hodges, JR | 1 |
| Mehta, MA | 1 |
| Nestor, PJ | 1 |
| Clark, L | 2 |
| Sahakian, BJ | 2 |
| DeVito, EE | 1 |
| Blackwell, AD | 1 |
| Kent, L | 1 |
| Ersche, KD | 1 |
| Salmond, CH | 1 |
| Dezsery, AM | 1 |
2 trials available for methylphenidate and Gambling, Pathologic
| Article | Year |
|---|---|
High reward expectancy during methylphenidate depresses the dopaminergic response to gain and loss.
Topics: Corpus Striatum; Dopamine; Double-Blind Method; Female; Functional Neuroimaging; Gambling; Humans; M | 2017 |
Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia.
Topics: Aged; Central Nervous System Stimulants; Cognition; Dementia; Double-Blind Method; Female; Gambling; | 2006 |
1 other study available for methylphenidate and Gambling, Pathologic
| Article | Year |
|---|---|
The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2008 |