methylphenidate has been researched along with Fatigue Syndrome, Chronic in 4 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fatigue scores fell significantly during methylphenidate intake in comparison with baseline (mean difference: -0." | 9.12 | Does methylphenidate reduce the symptoms of chronic fatigue syndrome? ( Blockmans, D; Bobbaers, H; Persoons, P; Van Houdenhove, B, 2006) |
| "Fatigue scores fell significantly during methylphenidate intake in comparison with baseline (mean difference: -0." | 5.12 | Does methylphenidate reduce the symptoms of chronic fatigue syndrome? ( Blockmans, D; Bobbaers, H; Persoons, P; Van Houdenhove, B, 2006) |
| "Treatment with methylphenidate resulted in complete resolution of symptoms in two patients and significant improvement in the other two." | 1.29 | Consideration of narcolepsy in the differential diagnosis of chronic fatigue syndrome. ( Ambrogetti, A; Olson, LG, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blockmans, D | 2 |
| Persoons, P | 2 |
| Van Houdenhove, B | 1 |
| Bobbaers, H | 1 |
| Valdizán Usón, JR | 1 |
| Idiazábal Alecha, MA | 1 |
| Ambrogetti, A | 1 |
| Olson, LG | 1 |
1 review available for methylphenidate and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Diagnostic and treatment challenges of chronic fatigue syndrome: role of immediate-release methylphenidate.
Topics: Central Nervous System Stimulants; Delayed-Action Preparations; Fatigue Syndrome, Chronic; Humans; M | 2008 |
2 trials available for methylphenidate and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Long-term methylphenidate intake in chronic fatigue syndrome.
Topics: Activities of Daily Living; Adult; Cross-Over Studies; Dopamine Uptake Inhibitors; Dose-Response Rel | 2016 |
Does methylphenidate reduce the symptoms of chronic fatigue syndrome?
Topics: Adult; Affect; Attention; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method | 2006 |
1 other study available for methylphenidate and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Consideration of narcolepsy in the differential diagnosis of chronic fatigue syndrome.
Topics: Adolescent; Diagnosis, Differential; Fatigue Syndrome, Chronic; Female; Humans; Male; Methylphenidat | 1994 |