Page last updated: 2024-10-31

methylphenidate and Enuresis

methylphenidate has been researched along with Enuresis in 16 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Enuresis: Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).

Research Excerpts

ExcerptRelevanceReference
"All patients responded positively with complete cessation of enuresis to varying dose schedules of methylphenidate."5.08Successful treatment of giggle incontinence with methylphenidate. ( Reinberg, Y; Sher, PK, 1996)
"A case is presented in which a hyperactive child with secondary enuresis had a dramatic response to both syndromes of methylphenidate therapy."3.66Enuresis: a new look at stimulant therapy. ( Diamond, JM; Stein, JM, 1983)
"Although the FDA recommends imipramine hydrochloride (IMI) only for temporary relief of symptoms of enuresis nocturna (EN), the drug has been applied to a number of other pediatric situations, including the Hyperkinetic Syndrome (HS), childhood depression, somnambulism and pavor nocturnus, school phobia, petit mal epilepsy, allergies, autism, encorpresis and head-banging."3.65Imipramine and children: a review and some speculations about the mechanism of drug action. ( Gualtieri, CT, 1977)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naguy, A1
Purper-Ouakil, D1
Chang, JH1
Lee, KY1
Kim, TB1
Yoon, SJ1
Lee, T1
Kim, KH1
Schulz-Juergensen, S1
Thiemann, A1
Gebhardt, J1
Baumgarten-Walczak, A1
Eggert, P1
BREGER, E2
DROOBY, AS1
LINKA, Z1
Baeyens, D1
Roeyers, H1
D'Haese, L1
Pieters, F1
Hoebeke, P1
Vande Walle, J1
Zhu, YG1
Xiao, YL1
Xu, WP1
Diamond, JM1
Stein, JM1
Sher, PK1
Reinberg, Y1
Eggers, C1
Gualtieri, CT1
White, JH1
Aman, MG1
Kern, RA1
Arnold, LE1
McGhee, DE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Characteristics of Prepulse Inhibition in Children and Adolescents Suffering From Attention Deficit Disorder: With and Without Medication.[NCT02344784]46 participants (Actual)Observational2015-01-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for methylphenidate and Enuresis

ArticleYear
[Use of psychotropic drugs in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:12

    Topics: Adolescent; Age Factors; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety Dis

2008
[Psychotropic drug therapy in children].
    Fortschritte der Medizin, 1977, Sep-08, Volume: 95, Issue:33

    Topics: Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Autistic Disorder;

1977

Trials

3 trials available for methylphenidate and Enuresis

ArticleYear
Prepulse inhibition of acoustic startle and the influence of methylphenidate in children with ADHD.
    Journal of attention disorders, 2014, Volume: 18, Issue:2

    Topics: Acoustic Stimulation; Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2014
Successful treatment of giggle incontinence with methylphenidate.
    The Journal of urology, 1996, Volume: 156, Issue:2 Pt 2

    Topics: Adolescent; Adult; Central Nervous System Stimulants; Child; Enuresis; Female; Follow-Up Studies; Hu

1996
Fenfluramine and mental retardation.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Double-Blind Method; Encopresis; Enuresis; Fenflurami

1991

Other Studies

11 other studies available for methylphenidate and Enuresis

ArticleYear
Duloxetine Alleviates Stimulant Dysphoria, Helps With Enuresis, and Complements Cognitive Response in an Adolescent With Attention-Deficit/Hyperactivity Disorder.
    The primary care companion for CNS disorders, 2016, Dec-29, Volume: 18, Issue:6

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cognit

2016
Clinical and urodynamic effect of methylphenidate for the treatment of giggle incontinence (enuresis risoria).
    Neurourology and urodynamics, 2011, Volume: 30, Issue:7

    Topics: Adolescent; Central Nervous System Stimulants; Child; Enuresis; Female; Humans; Laughter; Methylphen

2011
Hydroxyzine hydrochloride and methylphenidate hydrochloride in the management of enuresis.
    The Journal of pediatrics, 1962, Volume: 61

    Topics: Disease Management; Enuresis; Hydroxyzine; Methylphenidate; Nocturnal Enuresis

1962
The maintenance of therapeutic effect in children with enuresis. A follow-up study.
    The Journal of pediatrics, 1962, Volume: 61

    Topics: Child; Enuresis; Follow-Up Studies; Humans; Hydroxyzine; Meprobamate; Methylphenidate; Nocturnal Enu

1962
A RELIABLE TRUCE WITH ENURESIS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Adolescent; Amphetamine; Amphetamines; Atropa belladonna; Bromides; Child; Enuresis; Humans; Imipram

1964
[CENTEDRIN THERAPY OF NEUROSES AMONG ADOLESCENTS].
    Orvosi hetilap, 1964, Jul-19, Volume: 105

    Topics: Adolescent; Depression; Depressive Disorder; Drug Therapy; Enuresis; Humans; Methylphenidate; Neurot

1964
The prevalence of ADHD in children with enuresis: comparison between a tertiary and non-tertiary care sample.
    Acta paediatrica (Oslo, Norway : 1992), 2006, Volume: 95, Issue:3

    Topics: Academic Medical Centers; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stim

2006
[Therapeutic effect of ritalin on enuresis: experience of 40 cases].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2007, Volume: 9, Issue:1

    Topics: Child; Child, Preschool; Enuresis; Female; Humans; Male; Methylphenidate

2007
Enuresis: a new look at stimulant therapy.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Enuresis; Fe

1983
Imipramine and children: a review and some speculations about the mechanism of drug action.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Depression; Dopamine; Enuresis; Epilepsy, Absence;

1977
Practical use of psychotropic drugs in children.
    Texas medicine, 1976, Volume: 72, Issue:9

    Topics: Adolescent; Child; Child Behavior Disorders; Enuresis; Humans; Hyperkinesis; Imipramine; Methylpheni

1976