methylphenidate has been researched along with Dyskinesia, Drug-Induced in 26 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| " It has been known to have side effects such as dyskinesia, but this case details the emergence of dystonia and dyskinesia when the simultaneous use of methylphenidate and a phenothiazine was followed by withdrawal of the phenothiazine." | 7.66 | Methylphenidate, neuroleptics and dyskinesia-dystonia. ( Chapel, J; Husain, A; Malek-Ahmadi, P, 1980) |
| "In a child with minimal brain dysfunction, we found that chorea was related to the major central effect of methylphenidate and probably to the effect of the drug on central catecholaminergic systems." | 7.66 | Methylphenidate-induced chorea: case report and pharmacologic implications. ( Klawans, HL; Nausieda, PA; Weiner, WJ, 1978) |
| "To determine if repeated dosing with methylphenidate hydrochloride (MPD) (Ritalin; Novartis Pharmaceuticals, East Hanover, NJ), an inhibitor of the dopamine transporter, would augment the effects of oral levodopa in patients with Parkinson disease." | 5.12 | Effects of methylphenidate on response to oral levodopa: a double-blind clinical trial. ( Carlson, NE; Carter, JH; Nutt, JG, 2007) |
| " We report two cases of an adverse effect of dyskinesia and bruxism when MPH was given to children maintained on valproic acid." | 3.70 | Adverse response to methylphenidate in combination with valproic acid. ( Gara, L; Roberts, W, 2000) |
| " It has been known to have side effects such as dyskinesia, but this case details the emergence of dystonia and dyskinesia when the simultaneous use of methylphenidate and a phenothiazine was followed by withdrawal of the phenothiazine." | 3.66 | Methylphenidate, neuroleptics and dyskinesia-dystonia. ( Chapel, J; Husain, A; Malek-Ahmadi, P, 1980) |
| "In a child with minimal brain dysfunction, we found that chorea was related to the major central effect of methylphenidate and probably to the effect of the drug on central catecholaminergic systems." | 3.66 | Methylphenidate-induced chorea: case report and pharmacologic implications. ( Klawans, HL; Nausieda, PA; Weiner, WJ, 1978) |
| " Both groups were assessed for dyskinetic symptoms at ten weekly intervals as dosage was phased out in the neuroleptic group." | 2.66 | Dyskinetic symptoms in profoundly retarded residents following neuroleptic withdrawal and during methylphenidate treatment. ( Aman, MG; Singh, NN, 1985) |
| "Methylphenidate is a short-acting stimulant." | 1.39 | Methylphenidate-induced acute orofacial and extremity dyskinesia. ( Donmez, A; Isik, B; Orun, E; Sonmez, FM; Tas, T; Yilmaz, AE, 2013) |
| " Personal or family tic history, medication selection, or dosage was not related to onset of T/D." | 1.29 | Tics and dyskinesias associated with stimulant treatment in attention-deficit hyperactivity disorder. ( Adesman, AR; Goldstein, IJ; Lipkin, PH, 1994) |
| "Deanol did not produce the anticipated elevation in choline levels postulated to be one mechanism of its action." | 1.26 | Deanol acetamidobenzoate (Deaner) in tardive dyskinesia. ( Fann, WE; Stafford, JR, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naguy, A | 1 |
| Alrashidi, F | 1 |
| Elsori, DH | 1 |
| Waugh, JL | 1 |
| Kim, JY | 1 |
| Baik, JS | 1 |
| Yilmaz, AE | 1 |
| Donmez, A | 1 |
| Orun, E | 1 |
| Tas, T | 1 |
| Isik, B | 1 |
| Sonmez, FM | 1 |
| Senecky, Y | 1 |
| Lobel, D | 1 |
| Diamond, GW | 1 |
| Weitz, R | 1 |
| Inbar, D | 1 |
| Mendhekar, DN | 1 |
| Duggal, HS | 1 |
| Nutt, JG | 1 |
| Carter, JH | 1 |
| Carlson, NE | 1 |
| Tahiroglu, AY | 1 |
| Avci, A | 1 |
| Balázs, J | 1 |
| Besnyo, M | 1 |
| Gádoros, J | 1 |
| Hollis, CP | 1 |
| Thompson, A | 1 |
| Christensen, AV | 2 |
| Nielsen, IM | 2 |
| Gerlach, J | 1 |
| Bjørndal, N | 1 |
| Christensson, E | 1 |
| El-Defrawi, MH | 1 |
| Greenhill, LL | 1 |
| Radonjic, D | 1 |
| Lapierre, YD | 1 |
| Knott, V | 1 |
| Husain, A | 1 |
| Chapel, J | 1 |
| Malek-Ahmadi, P | 1 |
| Lieberman, JA | 3 |
| Alvir, J | 2 |
| Geisler, S | 1 |
| Ramos-Lorenzi, J | 2 |
| Woerner, M | 2 |
| Novacenko, H | 1 |
| Cooper, T | 1 |
| Kane, JM | 2 |
| Lipkin, PH | 1 |
| Goldstein, IJ | 1 |
| Adesman, AR | 1 |
| Connor, DF | 1 |
| Gara, L | 1 |
| Roberts, W | 1 |
| Jeste, DV | 1 |
| Wyatt, RJ | 1 |
| Weiner, WJ | 1 |
| Nausieda, PA | 1 |
| Klawans, HL | 1 |
| Stafford, JR | 1 |
| Fann, WE | 1 |
| Aman, MG | 1 |
| Singh, NN | 1 |
| Sarantakos, S | 1 |
| Gadaleta, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subacute Trial of Methylphenidate in Parkinson's Disease[NCT00359723] | Phase 2 | 13 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methylphenidate and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Prediction of outcome in first-episode schizophrenia.
Topics: Antipsychotic Agents; Dopamine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Growth Hormo | 1993 |
In search of treatment for tardive dyskinesia: review of the literature.
Topics: Amantadine; Antipsychotic Agents; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Levodop | 1979 |
4 trials available for methylphenidate and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Effects of methylphenidate on response to oral levodopa: a double-blind clinical trial.
Topics: Administration, Oral; Aged; Antiparkinson Agents; Cross-Over Studies; Dopamine Uptake Inhibitors; Do | 2007 |
Methylphenidate response, psychopathology and tardive dyskinesia as predictors of relapse in schizophrenia.
Topics: Adolescent; Adult; Blinking; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Follow-Up Studie | 1994 |
Dyskinetic symptoms in profoundly retarded residents following neuroleptic withdrawal and during methylphenidate treatment.
Topics: Adolescent; Adult; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, | 1985 |
Prediction of relapse in schizophrenia.
Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Blinking; Dopamine Antagonists; Dyskinesia | 1987 |
20 other studies available for methylphenidate and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Methylphenidate-induced "Moving Ear Syndrome" in a child with ADHD responding favorably to add-on propranolol.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dyskinesia, | 2019 |
Acute dyskinetic reaction in a healthy toddler following methylphenidate ingestion.
Topics: Acute Disease; Central Nervous System Stimulants; Dyskinesia, Drug-Induced; Humans; Male; Methylphen | 2013 |
Adult onset methylphenidate induced dyskinesia after stroke.
Topics: Central Nervous System Stimulants; Dyskinesia, Drug-Induced; Female; Humans; Male; Methylphenidate; | 2014 |
Methylphenidate-induced acute orofacial and extremity dyskinesia.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; C | 2013 |
Isolated orofacial dyskinesia: a methylphenidate-induced movement disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dose-Respon | 2002 |
Methylphenidate-induced rabbit syndrome.
Topics: Child; Dyskinesia, Drug-Induced; Humans; Male; Methylphenidate; Movement Disorders | 2006 |
Polypharmacy and EPS in a child; a case report.
Topics: Attention Deficit Disorder with Hyperactivity; Benztropine; Bipolar Disorder; Child; Comorbidity; Do | 2007 |
Methylphenidate-induced orofacial and extremity dyskinesia.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dyskinesia, | 2007 |
Acute dyskinesia on starting methylphenidate after risperidone withdrawal.
Topics: Acute Disease; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous | 2007 |
Dopaminergic supersensitivity: influence of dopamine agonists and drugs used for the treatment of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interac | 1980 |
Methylphenidate, apomorphine, THIP, and diazepam in monkeys: dopamine-GABA behavior related to psychoses and tardive dyskinesia.
Topics: Animals; Apomorphine; Chlorocebus aethiops; Diazepam; Dopamine; Drug Interactions; Dyskinesia, Drug- | 1984 |
Substituting stimulants in treating behavior disorders.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dyskinesia, Drug-Induced; Humans; Male; Methyl | 1984 |
The effect of methylphenidate on tardive dyskinesia.
Topics: Adult; Dyskinesia, Drug-Induced; Electromyography; Humans; Methylphenidate; Middle Aged; Motor Activ | 1981 |
Methylphenidate, neuroleptics and dyskinesia-dystonia.
Topics: Asthma; Child, Preschool; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Dystonia; Humans; Hyp | 1980 |
Tics and dyskinesias associated with stimulant treatment in attention-deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Chronic Disease; | 1994 |
Stimulants and neuroleptic withdrawal dyskinesia.
Topics: Aggression; Antipsychotic Agents; Central Nervous System Stimulants; Child; Drug Therapy, Combinatio | 1998 |
Adverse response to methylphenidate in combination with valproic acid.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Bruxism; Central Nervous System Stim | 2000 |
Dopaminergic supersensitivity: influence of dopamine agonists, cholinergics, anticholinergics, and drugs used for the treatment of tardive dyskinesia.
Topics: Animals; Antiparkinson Agents; Apomorphine; Atropine; Dopamine; Drug Synergism; Dyskinesia, Drug-Ind | 1979 |
Methylphenidate-induced chorea: case report and pharmacologic implications.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Child; Child, Preschool; Chorea; Dopa | 1978 |
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
Topics: Choline; Cyproheptadine; Deanol; Drug Evaluation; Dyskinesia, Drug-Induced; Ethanolamines; Humans; M | 1977 |