methylphenidate has been researched along with Drug Overdose in 19 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 14-year-old girl with suicidal ideation was presented to the paediatric hospital about 2 h after ingestion of 21 long-acting methylphenidate (MPH) 54-mg tablets (1,134 mg Concerta(®))." | 3.76 | Case report: intoxication with high dose of long-acting methylphenidate (Concerta(®)) in a suicidal 14-year-old girl. ( Burger, R; Gerlach, M; Klampfl, K; Pfuhlmann, B; Quattländer, A; Warnke, A, 2010) |
| "The FDA addressed interchangeability problems with generic modified-release alternatives of bupropion and methylphenidate including lack of bioequivalence, reduced efficacy, and increased incidence of adverse events." | 1.43 | Interchangeability, Safety and Efficacy of Modified-Release Drug Formulations in the USA: The Case of Opioid and Other Nervous System Drugs. ( Hansen, R; Rodriguez-Monguio, R; Seoane-Vazquez, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Vohra, V | 1 |
| King, A | 1 |
| Daviskiba, S | 1 |
| Reed, B | 1 |
| Rockhill, S | 1 |
| Kern, P | 1 |
| Dean, D | 1 |
| Bailey, GP | 1 |
| Ho, JH | 1 |
| Hudson, S | 1 |
| Dines, A | 1 |
| Archer, JR | 1 |
| Dargan, PI | 1 |
| Wood, DM | 1 |
| Seoane-Vazquez, E | 1 |
| Rodriguez-Monguio, R | 1 |
| Hansen, R | 1 |
| Dunlop, AJ | 1 |
| Newman, LK | 1 |
| Cairns, R | 1 |
| Daniels, B | 1 |
| Wood, DA | 1 |
| Brett, J | 1 |
| Fettahoglu, EC | 1 |
| Satilmis, A | 1 |
| Gokcen, C | 1 |
| Ozatalay, E | 1 |
| Hill, SL | 1 |
| El-Khayat, RH | 1 |
| Sandilands, EA | 1 |
| Thomas, SH | 1 |
| Poulton, A | 1 |
| Ozdemir, E | 1 |
| Karaman, MG | 1 |
| Yurteri, N | 1 |
| Erdogan, A | 1 |
| Klampfl, K | 1 |
| Quattländer, A | 1 |
| Burger, R | 1 |
| Pfuhlmann, B | 1 |
| Warnke, A | 1 |
| Gerlach, M | 1 |
| Ruwald, MH | 1 |
| Ruwald, AC | 1 |
| Tønder, N | 1 |
| Coetzee, M | 1 |
| Kaminer, Y | 1 |
| Morales, A | 1 |
| FIER, M | 1 |
| GOLDBERG, MA | 1 |
| Reimers, A | 1 |
| Langsetmo, HK | 1 |
| Massello, W | 1 |
| Carpenter, DA | 1 |
| Markowitz, JS | 1 |
| Logan, BK | 1 |
| Diamond, F | 1 |
| Patrick, KS | 1 |
| Klein-Schwartz, W | 1 |
| Lichtigfeld, FJ | 1 |
| Gillman, MA | 1 |
1 review available for methylphenidate and Drug Overdose
| Article | Year |
|---|---|
Abuse and toxicity of methylphenidate.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2002 |
18 other studies available for methylphenidate and Drug Overdose
| Article | Year |
|---|---|
Stimulant storm - state health department psychostimulant age-adjusted mortality rate correlates with psychostimulant-based Michigan Poison Center case exposures over time.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Dextroamphetamine; Drug Overdose; Female; Hum | 2021 |
Nopaine no gain: recreational ethylphenidate toxicity.
Topics: Adult; Anxiety; Arrhythmias, Cardiac; Central Nervous System; Central Nervous System Stimulants; Chr | 2015 |
Interchangeability, Safety and Efficacy of Modified-Release Drug Formulations in the USA: The Case of Opioid and Other Nervous System Drugs.
Topics: Analgesics, Opioid; Antidepressive Agents, Second-Generation; Bupropion; Centers for Medicare and Me | 2016 |
ADHD and psychostimulants - overdiagnosis and overprescription.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Drug Overdose; Fem | 2016 |
ADHD medication overdose and misuse: the NSW Poisons Information Centre experience, 2004-2014.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; | 2016 |
Oral megadose methylphenidate ingestion for suicide attempt.
Topics: Administration, Oral; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan | 2009 |
Electrocardiographic effects of methylphenidate overdose.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Drug Overdose; Electrocardiography; Female; He | 2010 |
Oral megadose methylphenidate ingestion for suicide attempt.
Topics: Administration, Oral; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan | 2010 |
A case of suicide attempt with long-acting methylphenidate (Concerta).
Topics: Adolescent; Central Nervous System Stimulants; Delayed-Action Preparations; Drug Overdose; Female; H | 2010 |
Case report: intoxication with high dose of long-acting methylphenidate (Concerta(®)) in a suicidal 14-year-old girl.
Topics: Adolescent; Central Nervous System Stimulants; Delayed-Action Preparations; Drug Overdose; Female; H | 2010 |
[Methylphenidate induced ST elevation acute myocardial infarction].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Coronary Vasospasm | 2012 |
Megadose intranasal methylphenidate (ritalin) abuse in adult attention deficit hyperactivity disorder.
Topics: Administration, Intranasal; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous Sy | 2002 |
CONVULSIVE SEIZURES IN CHLORPROTHIXENE OVERDOSE.
Topics: Black People; Chlorprothixene; Drug Overdose; Humans; Methylphenidate; Phenytoin; Seizures; Toxicolo | 1964 |
ADHD update: new data on the risks of medication.
Topics: Adrenergic Uptake Inhibitors; Adult; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hype | 2006 |
Combined overdose of atomoxetine and methylphenidate in a cytochrome P450 2D6 poor metabolizer.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Cytochrome P-450 CYP2D6; Drug O | 2007 |
A fatality due to the intranasal abuse of methylphenidate (Ritalin).
Topics: Administration, Intranasal; Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; | 1999 |
Detection of the novel metabolite ethylphenidate after methylphenidate overdose with alcohol coingestion.
Topics: Adult; Alcohol Drinking; Dose-Response Relationship, Drug; Drug Overdose; Drug Synergism; Female; Ga | 1999 |
Methylphenidate for reversal of drug-induced coma.
Topics: Adult; Barbiturates; Coma; Drug Overdose; Female; Humans; Methylphenidate | 1990 |