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methylphenidate and Drug Abuse, Intravenous

methylphenidate has been researched along with Drug Abuse, Intravenous in 28 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"To report the effects of intravenous abuse of pentazocine hydrochloride and methylphenidate hydrochloride during pregnancy."7.68Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome. ( Casiro, OG; Debooy, VD; Seshia, MM; Tenenbein, M, 1993)
" Some relationships previously revealed in our study setting, such as the known relationship between Talwin (pentazocine) and Ritalin (methylphenidate) use, injection in hotels, and hepatitis C virus prevalence, were confirmed through our cluster analysis approach."3.74Identifying heterogeneity among injection drug users: a cluster analysis approach. ( Jolly, AM; Shah, L; Shaw, SY; Wylie, JL, 2008)
"A 36-year-old patient presented with a severe hand ischemia after intraarterial injection of four dissolved tablets of Methylphenidate each 10 mg (Ritalin into the right radial artery."3.72[Acute ischemia after intraarterial drug injection]. ( Aschwanden, M; Jäger, KA; Kliem, M; Stürchler, M; Thalhammer, C, 2004)
"To report the effects of intravenous abuse of pentazocine hydrochloride and methylphenidate hydrochloride during pregnancy."3.68Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome. ( Casiro, OG; Debooy, VD; Seshia, MM; Tenenbein, M, 1993)
"Methylphenidate is an effective treatment for reducing intravenous drug use in patients with severe amphetamine dependence."2.73A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence. ( Föhr, J; Haukka, J; Kuikanmäki, O; Kuoppasalmi, K; Meririnne, E; Sokero, P; Tiihonen, J; Tuomola, P; Vorma, H, 2007)
"Methylphenidate (MPH) is a prescription stimulant used to treat attention-deficit hyperactivity disorder."1.46Methylphenidate disintegration from oral formulations for intravenous use by experienced substance users. ( Asgrimsson, V; Bjarnadottir, GD; Bragadottir, H; Haraldsson, HM; Johannsson, M; Magnusson, A; Rafnar, BO; Sigurdsson, E; Snorradottir, I; Steingrimsson, S, 2017)
"Lower lobe panacinar emphysema was more common in methylphenidate abusers (six [86%] of seven patients) than in non-mnethylphenidate drug abusers (one [20%] of five, p<0."1.31Talcosis associated with IV abuse of oral medications: CT findings. ( Godwin, JD; Heyneman, LE; Kazerooni, EA; Müller, NL; Reittner, P; Ward, S, 2000)
"Radiographs showed pulmonary emphysema in all cases."1.29Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. ( Frank, MS; Glenny, RW; Godwin, JD; Schmidt, RA; Schmutz, JF; Stern, EJ, 1994)
"These findings indicate that some intravenous drug abusers develop emphysema that clinically, radiologically, and pathologically resembles that caused by alpha-1-antitrypsin deficiency but which must have a different pathogenesis."1.28Panlobular emphysema in young intravenous Ritalin abusers. ( Cantino, ME; Glenny, RW; Godwin, JD; Hampson, NB; Reichenbach, DD; Schmidt, RA, 1991)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (28.57)18.2507
2000's10 (35.71)29.6817
2010's9 (32.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Shram, MJ1
Setnik, B1
Webster, L1
Guenther, S1
Mickle, TC1
Braeckman, R1
Kanski, J1
Martin, A1
Kelsh, D1
Vince, BD1
Barrett, AC1
Yeung, A1
Weir, A1
Austin, H1
Morrison, K1
Inverarity, D1
Sherval, J1
Henderson, N1
Joshi, S1
Ure, R1
McAuley, A1
Bjarnadottir, GD1
Johannsson, M1
Magnusson, A1
Rafnar, BO1
Sigurdsson, E1
Steingrimsson, S1
Asgrimsson, V1
Snorradottir, I1
Bragadottir, H1
Haraldsson, HM1
Pannett, M1
Goodall, K1
Bhutia, S1
Imbert, B1
Cohen, J1
Simon, N1
Frauger, E1
Amaslidou, D1
Spadari, M1
Allaria-Lapierre, V1
Braunstein, D1
Sciortino, V1
Thirion, X1
Djezzar, S1
Micallef, J2
Dahlman, D1
Håkansson, A1
Björkman, P1
Blomé, MA1
Kral, AH1
Lafferty, C1
Smith, L1
Coull, A1
Shanley, J1
Vérité, F1
Shaw, SY1
Shah, L1
Jolly, AM1
Wylie, JL1
Shlomi, D1
Shitrit, D1
Bendayan, D1
Sahar, G1
Shechtman, Y1
Kramer, MR1
Roux, P1
Carrieri, MP1
Keijzer, L1
Dasgupta, N1
Huss, M1
Lehmkuhl, U1
Thalhammer, C1
Aschwanden, M1
Kliem, M1
Stürchler, M1
Jäger, KA1
El-Jabali, F1
Cohen, S1
Gautschi, OP1
Zellweger, R1
Tiihonen, J1
Kuoppasalmi, K1
Föhr, J1
Tuomola, P1
Kuikanmäki, O1
Vorma, H1
Sokero, P1
Haukka, J1
Meririnne, E1
Hennink, M1
Abbas, Z1
Choudhri, Y1
Diener, T1
Lloyd, K1
Archibald, CP1
Cule, S1
Debooy, VD1
Seshia, MM1
Tenenbein, M1
Casiro, OG1
Carter, HS1
Watson, WA1
Stern, EJ1
Frank, MS1
Schmutz, JF1
Glenny, RW2
Schmidt, RA2
Godwin, JD3
Padley, SP1
Adler, BD1
Staples, CA1
Miller, RR1
Müller, NL2
Weinman, SA1
D'Agostino, JL1
Ward, S1
Heyneman, LE1
Reittner, P1
Kazerooni, EA1
Still, A1
Gordon, M1
Mercer, J1
Roake, J1
Kajiki, A1
Tsuda, T1
Yamazaki, H1
Kido, M1
Parran, TV1
Jasinski, DR1
Hampson, NB1
Cantino, ME1
Reichenbach, DD1

Reviews

2 reviews available for methylphenidate and Drug Abuse, Intravenous

ArticleYear
Accidental intra-arterial injection of methylphenidate into the radial artery.
    ANZ journal of surgery, 2019, Volume: 89, Issue:5

    Topics: Adult; Amputation, Surgical; Compartment Syndromes; Female; Fingers; Follow-Up Studies; Humans; Infa

2019
Methylphenidate and substance abuse: a review of pharmacology, animal, and clinical studies.
    Journal of attention disorders, 2002, Volume: 6 Suppl 1

    Topics: Administration, Oral; Animals; Central Nervous System Stimulants; Child; Humans; Longitudinal Studie

2002

Trials

2 trials available for methylphenidate and Drug Abuse, Intravenous

ArticleYear
Oral, intranasal, and intravenous abuse potential of serdexmethylphenidate, a novel prodrug of d-methylphenidate.
    Current medical research and opinion, 2022, Volume: 38, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cross-Over Studies

2022
A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence.
    The American journal of psychiatry, 2007, Volume: 164, Issue:1

    Topics: Adult; Amphetamine; Amphetamine-Related Disorders; Aripiprazole; Female; Humans; Male; Methylphenida

2007

Other Studies

24 other studies available for methylphenidate and Drug Abuse, Intravenous

ArticleYear
Assessing the impact of a temporary class drug order on ethylphenidate-related infections among people who inject drugs in Lothian, Scotland: an interrupted time-series analysis.
    Addiction (Abingdon, England), 2017, Volume: 112, Issue:10

    Topics: Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; Comorbidity; Disease Outbre

2017
Methylphenidate disintegration from oral formulations for intravenous use by experienced substance users.
    Drug and alcohol dependence, 2017, 09-01, Volume: 178

    Topics: Administration, Intravenous; Administration, Oral; Adult; Attention Deficit Disorder with Hyperactiv

2017
Intravenous abuse of methylphenidate.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:5

    Topics: Adult; Central Nervous System Stimulants; Drug Users; Humans; Injections, Intravenous; Male; Methylp

2013
Patterns of Methylphenidate Use and Assessment of Its Abuse among the General Population and Individuals with Drug Dependence.
    European addiction research, 2016, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Databases, Factual; Epidemiological Monitoring; Female; France; Humans; Insurance

2016
Correlates of Skin and Soft Tissue Infections in Injection Drug Users in a Syringe-Exchange Program in Malmö, Sweden.
    Substance use & misuse, 2015, Volume: 50, Issue:12

    Topics: Adult; Amphetamine-Related Disorders; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Drug

2015
The experience of an increase in the injection of ethylphenidate in Lothian April 2014-March 2015.
    Scottish medical journal, 2016, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Aged; Central Nervous System Stimulants; Commerce; Female; Humans; Injections; Ma

2016
[Acute psychiatric symptoms during methylphenidate intravenous injections: A case report].
    Therapie, 2017, Volume: 72, Issue:3

    Topics: Adult; Akathisia, Drug-Induced; Central Nervous System Stimulants; Delirium; Humans; Injections, Int

2017
Identifying heterogeneity among injection drug users: a cluster analysis approach.
    American journal of public health, 2008, Volume: 98, Issue:8

    Topics: Adolescent; Adult; Analgesics, Opioid; Central Nervous System Stimulants; Cluster Analysis; Cross-Se

2008
Successful lung transplantation for talcosis secondary to intravenous abuse of oral drug.
    International journal of chronic obstructive pulmonary disease, 2008, Volume: 3, Issue:2

    Topics: Central Nervous System Stimulants; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Injec

2008
Reducing harm from injecting pharmaceutical tablet or capsule material by injecting drug users.
    Drug and alcohol review, 2011, Volume: 30, Issue:3

    Topics: Buprenorphine; Capsules; Chemistry, Pharmaceutical; France; Harm Reduction; Humans; Methylphenidate;

2011
[Acute ischemia after intraarterial drug injection].
    Deutsche medizinische Wochenschrift (1946), 2004, Nov-05, Volume: 129, Issue:45

    Topics: Acute Disease; Adult; Amputation, Surgical; Anti-Inflammatory Agents; Anticoagulants; Central Nervou

2004
Images in clinical medicine. Talc retinopathy.
    The New England journal of medicine, 2006, Mar-23, Volume: 354, Issue:12

    Topics: Adult; Female; Hepatitis C, Chronic; Humans; Liver; Methylphenidate; Retina; Substance Abuse, Intrav

2006
Necrotising myositis after intravenous methylphenidat (Ritalin) injection.
    Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:9

    Topics: Adult; Central Nervous System Stimulants; Humans; Injections, Intravenous; Male; Methylphenidate; My

2006
Risk behaviours for infection with HIV and hepatitis C virus among people who inject drugs in Regina, Saskatchewan.
    Canada communicable disease report = Releve des maladies transmissibles au Canada, 2007, Mar-01, Volume: 33, Issue:5

    Topics: Adult; Chlamydia Infections; Cocaine-Related Disorders; Condoms; Cross-Sectional Studies; Female; Go

2007
Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome.
    American journal of diseases of children (1960), 1993, Volume: 147, Issue:10

    Topics: Adolescent; Adult; Developmental Disabilities; Female; Fetal Growth Retardation; Follow-Up Studies;

1993
IV pentazocine/methylphenidate abuse--the clinical toxicity of another Ts and blues combination.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:5

    Topics: Adult; Drug Combinations; Emergency Service, Hospital; Female; Humans; Male; Methylphenidate; Pentaz

1994
Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans.
    AJR. American journal of roentgenology, 1994, Volume: 162, Issue:3

    Topics: Adult; Female; Humans; Lung; Male; Methylphenidate; Middle Aged; Pulmonary Emphysema; Retrospective

1994
Pulmonary talcosis: CT findings in three cases.
    Radiology, 1993, Volume: 186, Issue:1

    Topics: Adult; Female; Granuloma, Foreign-Body; Humans; Lung Diseases; Male; Methylphenidate; Middle Aged; P

1993
Pyrogenic reaction after intravenous injection of pentazocine and methylphenidate.
    Journal of emergency nursing, 1993, Volume: 19, Issue:1

    Topics: Adult; Education, Nursing, Continuing; Fever; Humans; Male; Methylphenidate; Pentazocine; Substance

1993
Talcosis associated with IV abuse of oral medications: CT findings.
    AJR. American journal of roentgenology, 2000, Volume: 174, Issue:3

    Topics: Adult; Central Nervous System Stimulants; Diagnosis, Differential; Female; Foreign-Body Reaction; Gr

2000
Ritalin: drug of abuse. Two case reports of intra-arterial injection.
    The New Zealand medical journal, 2001, Nov-23, Volume: 114, Issue:1144

    Topics: Adult; Aneurysm, False; Arterial Occlusive Diseases; Central Nervous System Stimulants; Femoral Arte

2001
[Two cases of chronic respiratory failure in intravenous methylphenidate (Ritalin) abusers].
    Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:7

    Topics: Adult; Chronic Disease; Humans; Lung Diseases, Obstructive; Male; Methylphenidate; Middle Aged; Resp

1992
Intravenous methylphenidate abuse. Prototype for prescription drug abuse.
    Archives of internal medicine, 1991, Volume: 151, Issue:4

    Topics: Adult; Baltimore; Female; Humans; Lung Diseases; Male; Methylphenidate; Substance Abuse Treatment Ce

1991
Panlobular emphysema in young intravenous Ritalin abusers.
    The American review of respiratory disease, 1991, Volume: 143, Issue:3

    Topics: Adult; Electron Probe Microanalysis; Female; Humans; Lung; Male; Methylphenidate; Middle Aged; Pulmo

1991