methylphenidate has been researched along with Delayed Effects, Prenatal Exposure in 18 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aims of this review were to summarize the scientific evidence about the risks of using methylphenidate for ADHD in pregnancy and lactation, to present a case in which interruption of treatment after delivery and during breastfeeding was harmful and to discuss the implications of treating or not treating ADHD in pregnancy and lactation." | 8.90 | Methylphenidate use in pregnancy and lactation: a systematic review of evidence. ( Bolea-Alamanac, BM; Davies, SJ; Green, A; Maxwell, P; Verma, G, 2014) |
| "Methylphenidate (MPH) is a central nervous system stimulant drug that increases concentration and energy level." | 5.43 | Investigation of possible teratogenic effects in the offspring of mice exposed to methylphenidate during pregnancy. ( Bacchi, AD; Costa, Gde A; Galvão, TC; Moreira, EG; Salles, MJ, 2016) |
| "The aims of this review were to summarize the scientific evidence about the risks of using methylphenidate for ADHD in pregnancy and lactation, to present a case in which interruption of treatment after delivery and during breastfeeding was harmful and to discuss the implications of treating or not treating ADHD in pregnancy and lactation." | 4.90 | Methylphenidate use in pregnancy and lactation: a systematic review of evidence. ( Bolea-Alamanac, BM; Davies, SJ; Green, A; Maxwell, P; Verma, G, 2014) |
| "Maternal smoking during pregnancy, a form of developmental nicotine exposure (DNE), is associated with increased nicotine use and neurodevelopmental disorders such as ADHD in children." | 3.91 | Developmental nicotine exposure precipitates multigenerational maternal transmission of nicotine preference and ADHD-like behavioral, rhythmometric, neuropharmacological, and epigenetic anomalies in adolescent mice. ( Buck, JM; Knopik, VS; O'Neill, HC; Sanders, KN; Stitzel, JA; Wageman, CR, 2019) |
| "Cigarette smoking, nicotine replacement therapy, and smokeless tobacco use during pregnancy are associated with cognitive disabilities later in life in children exposed prenatally to nicotine." | 3.78 | Prenatal nicotine exposure mouse model showing hyperactivity, reduced cingulate cortex volume, reduced dopamine turnover, and responsiveness to oral methylphenidate treatment. ( Bhide, PG; Biederman, J; Spencer, TJ; Xu, Y; Zhang, X; Zhu, J, 2012) |
| "The main reason for pharmacological treatment of FASD children is attention deficit hyperactivity disorder (ADHD), and methylphenidate (MPH) is the drug of choice." | 1.72 | Influence of ( Białecka, M; Brzuchalski, B; Grzywacz, E; Machoy-Mokrzyńska, A; Malinowski, D; Pierzchlińska, A; Śmiarowska, M, 2022) |
| "Methylphenidate (MPH) is a central nervous system stimulant drug that increases concentration and energy level." | 1.43 | Investigation of possible teratogenic effects in the offspring of mice exposed to methylphenidate during pregnancy. ( Bacchi, AD; Costa, Gde A; Galvão, TC; Moreira, EG; Salles, MJ, 2016) |
| "Methylphenidate (MPH) is a commonly-used medication for the treatment of children with Attention-Deficit/Hyperactivity Disorders (ADHD)." | 1.40 | Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats. ( Belzung, C; Castelnau, P; Chalon, S; Cortese, S; Emond, P; Faraone, SV; Galineau, L; Lepelletier, FX; Nicolas, C; Solinas, M; Tauber, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Śmiarowska, M | 1 |
| Brzuchalski, B | 1 |
| Grzywacz, E | 1 |
| Malinowski, D | 1 |
| Machoy-Mokrzyńska, A | 1 |
| Pierzchlińska, A | 1 |
| Białecka, M | 1 |
| Bang Madsen, K | 1 |
| Robakis, TK | 1 |
| Liu, X | 1 |
| Momen, N | 1 |
| Larsson, H | 1 |
| Dreier, JW | 1 |
| Kildegaard, H | 1 |
| Groth, JB | 1 |
| Newcorn, JH | 1 |
| Hove Thomsen, P | 1 |
| Munk-Olsen, T | 1 |
| Bergink, V | 1 |
| Aoki, S | 1 |
| Kaizaki-Mitsumoto, A | 1 |
| Hattori, N | 1 |
| Numazawa, S | 1 |
| Buck, JM | 1 |
| Sanders, KN | 1 |
| Wageman, CR | 1 |
| Knopik, VS | 1 |
| Stitzel, JA | 1 |
| O'Neill, HC | 1 |
| Bolea-Alamanac, BM | 1 |
| Green, A | 1 |
| Verma, G | 1 |
| Maxwell, P | 1 |
| Davies, SJ | 1 |
| Lloyd, SA | 1 |
| Oltean, C | 1 |
| Pass, H | 1 |
| Phillips, B | 1 |
| Staton, K | 1 |
| Robertson, CL | 1 |
| Shanks, RA | 1 |
| Lepelletier, FX | 1 |
| Tauber, C | 1 |
| Nicolas, C | 1 |
| Solinas, M | 1 |
| Castelnau, P | 1 |
| Belzung, C | 1 |
| Emond, P | 1 |
| Cortese, S | 1 |
| Faraone, SV | 1 |
| Chalon, S | 1 |
| Galineau, L | 1 |
| Zubedat, S | 1 |
| Aga-Mizrachi, S | 1 |
| Cymerblit-Sabba, A | 1 |
| Ritter, A | 1 |
| Nachmani, M | 1 |
| Avital, A | 1 |
| Kung, TS | 1 |
| Richardson, JR | 1 |
| Cooper, KR | 1 |
| White, LA | 1 |
| Juárez, J | 1 |
| Guerrero-Álvarez, Á | 1 |
| Costa, Gde A | 1 |
| Galvão, TC | 1 |
| Bacchi, AD | 1 |
| Moreira, EG | 1 |
| Salles, MJ | 1 |
| Pagerols, M | 1 |
| Richarte, V | 1 |
| Sánchez-Mora, C | 1 |
| Garcia-Martínez, I | 1 |
| Corrales, M | 1 |
| Corominas, M | 1 |
| Cormand, B | 1 |
| Casas, M | 1 |
| Ribasés, M | 1 |
| Ramos-Quiroga, JA | 1 |
| Zhu, J | 2 |
| Fan, F | 1 |
| McCarthy, DM | 1 |
| Zhang, L | 1 |
| Cannon, EN | 1 |
| Spencer, TJ | 2 |
| Biederman, J | 2 |
| Bhide, PG | 2 |
| Torres-Reveron, A | 1 |
| Weedon, J | 1 |
| Dow-Edwards, DL | 1 |
| Zhang, X | 1 |
| Xu, Y | 1 |
| Choong, KC | 1 |
| Shen, RY | 1 |
| McFadyen-Leussis, MP | 1 |
| Lewis, SP | 1 |
| Bond, TL | 1 |
| Carrey, N | 1 |
| Brown, RE | 1 |
| Herning, RI | 1 |
1 review available for methylphenidate and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Methylphenidate use in pregnancy and lactation: a systematic review of evidence.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Breast Feeding; Child Development; Female | 2014 |
17 other studies available for methylphenidate and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Influence of
Topics: Attention Deficit Disorder with Hyperactivity; Catechol O-Methyltransferase; Child; Female; Fetal Al | 2022 |
In utero exposure to ADHD medication and long-term offspring outcomes.
Topics: Adult; Amphetamines; Attention Deficit Disorder with Hyperactivity; Child, Preschool; Clonidine; Coh | 2023 |
Fetal methylphenidate exposure induced ADHD-like phenotypes and decreased Drd2 and Slc6a3 expression levels in mouse offspring.
Topics: Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Dopamine Plasma Membrane T | 2021 |
Developmental nicotine exposure precipitates multigenerational maternal transmission of nicotine preference and ADHD-like behavioral, rhythmometric, neuropharmacological, and epigenetic anomalies in adolescent mice.
Topics: Adolescent; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Corpus Striatu | 2019 |
Prenatal exposure to psychostimulants increases impulsivity, compulsivity, and motivation for rewards in adult mice.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Compulsive Behavior; Female; Impulsive | 2013 |
Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.
Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dietary Sucrose; Disease Models, Animal; | 2014 |
Methylphenidate and environmental enrichment ameliorate the deleterious effects of prenatal stress on attention functioning.
Topics: Animals; Anxiety; Attention; Behavior, Animal; Central Nervous System Stimulants; Environment; Femal | 2015 |
Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish.
Topics: Animals; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Insecticides; Methy | 2015 |
Effects of methylphenidate and atomoxetine on impulsivity and motor activity in preadolescent rats prenatally-treated with alcohol.
Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Central Nervous System Depressants | 2015 |
Investigation of possible teratogenic effects in the offspring of mice exposed to methylphenidate during pregnancy.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Female; Gestatio | 2016 |
Pharmacogenetics of methylphenidate response and tolerability in attention-deficit/hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Chi-Sq | 2017 |
A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Attention Deficit Disorder with Hypera | 2017 |
Methylphenidate response in prenatal cocaine-exposed rats: a behavioral and brain functional study.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibi | 2010 |
Prenatal nicotine exposure mouse model showing hyperactivity, reduced cingulate cortex volume, reduced dopamine turnover, and responsiveness to oral methylphenidate treatment.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine; Female; Gy | 2012 |
Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Elec | 2004 |
Prenatal exposure to methylphenidate hydrochloride decreases anxiety and increases exploration in mice.
Topics: Animals; Anxiety; Exploratory Behavior; Female; Male; Maze Learning; Methylphenidate; Mice; Pregnanc | 2004 |
Cognitive event-related potentials in populations at risk for substance abuse.
Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 1996 |