Page last updated: 2024-10-31

methylphenidate and Conduct Disorder

methylphenidate has been researched along with Conduct Disorder in 43 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Conduct Disorder: A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"This study investigated the safety and efficacy of adding the atypical antipsychotic quetiapine to ongoing OROS methylphenidate treatment for adolescents with comorbid ADHD and severe aggression that were incompletely responsive to methylphenidate monotherapy."9.12Quetiapine addition in methylphenidate treatment-resistant adolescents with comorbid ADHD, conduct/oppositional-defiant disorder, and aggression: a prospective, open-label study. ( Bohnstedt, BN; Dunn, DW; Giauque, AL; Kronenberger, WG; Lafata, DE; Maxey, LE, 2007)
"A pilot comparison of the safety and efficacy of methylphenidate (MPH) combined with clonidine, clonidine monotherapy, or MPH monotherapy in 6- to 16-year-old children diagnosed with attention deficit hyperactivity disorder (ADHD) and comorbid aggressive oppositional defiant disorder or conduct disorder was completed."9.09A pilot study of methylphenidate, clonidine, or the combination in ADHD comorbid with aggressive oppositional defiant or conduct disorder. ( Barkley, RA; Connor, DF; Davis, HT, 2000)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."6.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"Methylphenidate has short-term positive effects on children and adolescents with CD."6.68Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder. ( Abikoff, H; Ganeles, D; Klass, E; Klein, RG; Pollack, S; Seese, LM, 1997)
"Conduct disorder was significantly higher in patients with DP, whereas ODD was significantly higher in the DESR and non-ED groups (P < 0."5.46Effect of Methylphenidate on Emotional Dysregulation in Children With Attention-Deficit/Hyperactivity Disorder + Oppositional Defiant Disorder/Conduct Disorder. ( Akyol Ardic, U; Ercan, ES; Kutlu, A, 2017)
"Methylphenidate treatment for ADHD and CD has acute effects on these processes."5.43Acute effects of methylphenidate on impulsivity and attentional behavior among adolescents comorbid for ADHD and conduct disorder. ( Acheson, A; Dougherty, DM; Hill-Kapturczak, N; Mathias, CW; Olvera, RL; Ryan, SR, 2016)
"Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score."5.40Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder. ( Bilgiç, A; Hergüner, S; Yılmaz, S, 2014)
" To determine (1) the serum baseline daily variations and nocturnal excretion of melatonin in ADHD subtypes and (2) the effect of chronic administration of methylphenidate, as well as the effects on symptomatology, 136 children with ADHD (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision: DSM-IV-TR criteria) were divided into subgroups using the "Children's Depression Inventory" (CDI)."5.19Methylphenidate ameliorates depressive comorbidity in ADHD children without any modification on differences in serum melatonin concentration between ADHD subtypes. ( Cubero-Millán, I; Fernández-López, L; Luna-del-Castillo, JD; Machado-Casas, I; Martínez-Serrano, S; Molina-Carballo, A; Muñoz-Hoyos, A; Ruiz-López, A; Tortosa-Pinto, P; Uberos, J, 2014)
"This study investigated the safety and efficacy of adding the atypical antipsychotic quetiapine to ongoing OROS methylphenidate treatment for adolescents with comorbid ADHD and severe aggression that were incompletely responsive to methylphenidate monotherapy."5.12Quetiapine addition in methylphenidate treatment-resistant adolescents with comorbid ADHD, conduct/oppositional-defiant disorder, and aggression: a prospective, open-label study. ( Bohnstedt, BN; Dunn, DW; Giauque, AL; Kronenberger, WG; Lafata, DE; Maxey, LE, 2007)
"A pilot comparison of the safety and efficacy of methylphenidate (MPH) combined with clonidine, clonidine monotherapy, or MPH monotherapy in 6- to 16-year-old children diagnosed with attention deficit hyperactivity disorder (ADHD) and comorbid aggressive oppositional defiant disorder or conduct disorder was completed."5.09A pilot study of methylphenidate, clonidine, or the combination in ADHD comorbid with aggressive oppositional defiant or conduct disorder. ( Barkley, RA; Connor, DF; Davis, HT, 2000)
"The aim of this study was to compare the effect of methylphenidate (MPH) versus MPH + parent training in children with ADHD and oppositional defiant disorder/conduct disorder (ODD/CD) over a 12-month period."3.80No beneficial effects of adding parent training to methylphenidate treatment for ADHD + ODD/CD children: a 1-year prospective follow-up study. ( Ardic, UA; Durak, S; Ercan, ES; Kutlu, A, 2014)
" The average dosage of MPH in the group with ADHD was 0."2.84Empathy and Facial Expression Recognition in Children With and Without Attention-Deficit/Hyperactivity Disorder: Effects of Stimulant Medication on Empathic Skills in Children with Attention-Deficit/Hyperactivity Disorder. ( Gokce, S; Gumustas, F; Sabuncuoglu, O; Yilmaz, I; Yulaf, Y, 2017)
"3%) of 65 children was reduced sufficiently after stimulant dosage adjustment and behavioral therapy to preclude adjunctive medication."2.75Stimulant-responsive and stimulant-refractory aggressive behavior among children with ADHD. ( Blader, JC; Jensen, PS; Kafantaris, V; Pliszka, SR; Schooler, NR, 2010)
" Children whose aggressive behavior persisted at the conclusion of the lead-in phase were randomly assigned to receive double-blind, flexibly dosed divalproex or a placebo adjunctive to stimulant for 8 weeks."2.74Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. ( Blader, JC; Jensen, PS; Kafantaris, V; Pliszka, SR; Schooler, NR, 2009)
" The results from the literature underline the necessity of caution and patient monitoring when risperidone dosing is modified during methylphenidate therapy."2.72Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance. ( Burden, AM; Stämpfli, D; Weiler, S, 2021)
"Methylphenidate has short-term positive effects on children and adolescents with CD."2.68Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder. ( Abikoff, H; Ganeles, D; Klass, E; Klein, RG; Pollack, S; Seese, LM, 1997)
"Although the relationship between attention-deficit/hyperactivity disorder (ADHD) and transport accidents has been shown, there is limited information on the relationship between medication and dose-response effects and transport accident risk."1.62Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH. ( Chen, VC; Chen, YL; Gossop, M; Liu, YC; Yang, YH, 2021)
"Conduct disorder (CD) and oppositional defiant disorder (ODD), collectively termed disruptive behavior disorders (DBDs), are a major cause of impairment and suffering in those affected by these conditions and their families and communities."1.48Does Methylphenidate Normalize Brain Dysfunction During Fear Learning in Adolescents With Disruptive Behavior Disorders? ( Fairchild, G, 2018)
"Conduct disorder was significantly higher in patients with DP, whereas ODD was significantly higher in the DESR and non-ED groups (P < 0."1.46Effect of Methylphenidate on Emotional Dysregulation in Children With Attention-Deficit/Hyperactivity Disorder + Oppositional Defiant Disorder/Conduct Disorder. ( Akyol Ardic, U; Ercan, ES; Kutlu, A, 2017)
"Methylphenidate treatment for ADHD and CD has acute effects on these processes."1.43Acute effects of methylphenidate on impulsivity and attentional behavior among adolescents comorbid for ADHD and conduct disorder. ( Acheson, A; Dougherty, DM; Hill-Kapturczak, N; Mathias, CW; Olvera, RL; Ryan, SR, 2016)
"Diagnoses of SUD and alcohol abuse were obtained from The Danish Psychiatric Central Register."1.40ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - a naturalistic long-term follow-up study. ( Dalsgaard, S; Frydenberg, M; Mortensen, PB; Thomsen, PH, 2014)
"Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score."1.40Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder. ( Bilgiç, A; Hergüner, S; Yılmaz, S, 2014)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.65)18.7374
1990's4 (9.30)18.2507
2000's17 (39.53)29.6817
2010's18 (41.86)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Stämpfli, D1
Weiler, S1
Burden, AM1
Liu, YC1
Chen, VC1
Yang, YH1
Chen, YL1
Gossop, M1
Gumustas, F1
Yilmaz, I1
Yulaf, Y1
Gokce, S1
Sabuncuoglu, O2
Gnanavel, S1
Fairchild, G1
Zoratto, F1
Franchi, F1
Macrì, S1
Laviola, G1
Dalsgaard, S1
Mortensen, PB1
Frydenberg, M1
Thomsen, PH1
Yılmaz, S1
Bilgiç, A1
Hergüner, S1
Blader, JC3
Pliszka, SR4
Kafantaris, V3
Foley, CA1
Crowell, JA1
Carlson, GA1
Sauder, CL1
Margulies, DM1
Sinha, C1
Sverd, J1
Matthews, TL1
Bailey, BY1
Daviss, WB1
Javelot, H1
Glay-Ribau, C1
Ligier, F1
Weiner, L1
Didelot, N1
Messaoudi, M1
Socha, M1
Body-Lawson, F1
Kabuth, B1
Rubia, K1
Alegría, AA1
Brinson, H1
Cubero-Millán, I1
Molina-Carballo, A1
Machado-Casas, I1
Fernández-López, L1
Martínez-Serrano, S1
Tortosa-Pinto, P1
Ruiz-López, A1
Luna-del-Castillo, JD1
Uberos, J1
Muñoz-Hoyos, A1
Helseth, SA1
Waschbusch, DA3
Gnagy, EM1
Onyango, AN1
Burrows-MacLean, L1
Fabiano, GA1
Coles, EK1
Chacko, A1
Wymbs, BT1
Walker, KS1
Wymbs, FA1
Garefino, A1
Massetti, GM1
Robb Mazzant, J1
Hoffman, MT1
Waxmonsky, JG1
Nichols-Lopez, K1
Pelham, WE3
Dougherty, DM1
Olvera, RL1
Acheson, A1
Hill-Kapturczak, N1
Ryan, SR1
Mathias, CW1
Kutlu, A2
Akyol Ardic, U1
Ercan, ES3
Karama, S1
Ben Amor, L1
Grizenko, N2
Ciampi, A1
Mbekou, V1
Ter-Stepanian, M2
Lageix, P1
Baron, C1
Schwartz, G1
Joober, R2
King, S2
Frankland, BW1
Andrade, BF1
Jacques, S1
Corkum, PV1
Dopheide, JA1
Schooler, NR2
Jensen, PS2
Rothermel, B1
Poustka, L1
Banaschewski, T2
Becker, K1
Zappitelli, M1
Ardic, UA1
Durak, S1
Tamm, L1
Trello-Rishel, K1
Riggs, P1
Nakonezny, PA1
Acosta, M1
Bailey, G1
Winhusen, T1
Hazell, PL1
Stuart, JE1
ZIMMERMAN, FT1
BURGEMEISTER, BB1
GROSS, MD1
WILSON, WC1
Yamashita, T1
Wada, Y1
Shiomi, S1
Nakane, A1
Taylor, E1
Döpfner, M2
Sergeant, J1
Asherson, P1
Buitelaar, J1
Coghill, D1
Danckaerts, M1
Rothenberger, A1
Sonuga-Barke, E1
Steinhausen, HC1
Zuddas, A1
Varan, A1
Deniz, U1
Craig, R1
Kronenberger, WG2
Giauque, AL2
Lafata, DE1
Bohnstedt, BN1
Maxey, LE1
Dunn, DW2
Sinzig, J1
Lehmkuhl, G1
Uebel, H1
Schmeck, K1
Poustka, F1
Gerber, WD1
Günter, M1
Knölker, U1
Gehrke, M1
Hässler, F1
Resch, F1
Brünger, M1
Ose, C1
Fischer, R1
Maia, CR1
Matte, BC1
Ludwig, HT1
Rohde, LA1
Szobot, CM1
Bukstein, O1
Handen, BL1
Janosky, J1
McAuliffe, S1
Klein, RG1
Abikoff, H1
Klass, E1
Ganeles, D1
Seese, LM1
Pollack, S1
Kolko, DJ1
Bukstein, OG1
Barron, J1
Weller, EB1
Rowan, A1
Elia, J1
Weller, RA1
Connor, DF1
Barkley, RA1
Davis, HT1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-Blind, Placebo-Controlled Trial of Flexible Dose Divalproex Sodium Adjunctive to Stimulant Treatment for Aggressive Children With Attention-Deficit Hyperactivity Disorder[NCT00228046]Phase 440 participants (Anticipated)Interventional2004-01-31Completed
Adjunctive Treatment With Divalproex or Risperidone for Aggression Refractory to Stimulant Monotherapy Among Children With ADHD[NCT00794625]Phase 4270 participants (Anticipated)Interventional2008-11-30Recruiting
Virtual Reality Attention Management Program for Improving Attention in Children[NCT03221244]50 participants (Anticipated)Interventional2016-06-02Recruiting
Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)[NCT00483106]Phase 4885 participants (Actual)Interventional1999-11-30Completed
Randomized Controlled Trial of Osmotic-Release Methylphenidate (OROS-MPH) for Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)[NCT00264797]Phase 3303 participants (Actual)Interventional2006-02-28Completed
Multimodal Treatment Study of Children With ADHD[NCT00000388]Phase 40 participants Interventional1998-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

ADHD Severity

DSM IV ADHD Rating Scale (ADHD-RS) adolescent informant, ascertained at baseline and weekly throughout the 16 week study. This scale is an 18-item symptom checklist of self-reported adolescent ADHD symptoms. Symptoms are scored as None (0), Mild (1), Moderate (2), and Severe (3), with a summary total of scores for the 18 symptoms. Possible scores range from 0 to 54, with higher scores indicating greater severity. Outcome is measured as the decrease in total severity score over time. (NCT00264797)
Timeframe: baseline and 20 weeks

Interventionunits on a scale (Mean)
Methylphenidate-20.6
Methylphenidate (Placebo)-21.8

OROS-MPH Abuse Liability

Assessed by pill counts in conjunction with weekly review of subjects' medication diaries and self-reported medication compliance. (NCT00264797)
Timeframe: 20 weeks

Interventionpills (Mean)
Methylphenidate15.4
Methylphenidate (Placebo)9.7

Substance Use

The change in number of days of substance use from baseline to end of the trial. The number of days of non-tobacco drug/alcohol ascertained using standard timeline follow back (TLFB) procedures. (NCT00264797)
Timeframe: 20 weeks

Interventiondays (Mean)
Methylphenidate-5.7
Methylphenidate (Placebo)-5.2

Substance Use Outcomes

The mean number of negative urine drug screens (UDS). (NCT00264797)
Timeframe: 20 weeks

Interventionnegative UDS (Mean)
Methylphenidate3.8
Methylphenidate (Placebo)2.8

Reviews

7 reviews available for methylphenidate and Conduct Disorder

ArticleYear
Movement disorders and use of risperidone and methylphenidate: a review of case reports and an analysis of the WHO database in pharmacovigilance.
    European child & adolescent psychiatry, 2021, Volume: 30, Issue:7

    Topics: Attention Deficit Disorder with Hyperactivity; Combined Modality Therapy; Comorbidity; Conduct Disor

2021
Brain abnormalities in attention-deficit hyperactivity disorder: a review.
    Revista de neurologia, 2014, Feb-24, Volume: 58 Suppl 1

    Topics: Adolescent; Adult; Atomoxetine Hydrochloride; Attention Deficit and Disruptive Behavior Disorders; A

2014
Attention-deficit-hyperactivity disorder: an update.
    Pharmacotherapy, 2009, Volume: 29, Issue:6

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Amphetamine; Antidepressive Agents, Second-Generati

2009
[Conduct disorder confined to the family context].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Adolescent; Central Nervous System Stimulants; Child; Child, Preschool; Conduct Disorder; Domestic V

2003
[Conduct disorder, unsocialized and socialized].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Antipsychotic Agents; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Central Nerv

2003
Attention deficit hyperactivity disorder and substance use disorders.
    Child and adolescent psychiatric clinics of North America, 2008, Volume: 17, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bupropion; Central Nervous System Stimula

2008
Aggressive behavior in patients with attention-deficit/hyperactivity disorder, conduct disorder, and pervasive developmental disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 15

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child D

1999

Trials

19 trials available for methylphenidate and Conduct Disorder

ArticleYear
Empathy and Facial Expression Recognition in Children With and Without Attention-Deficit/Hyperactivity Disorder: Effects of Stimulant Medication on Empathic Skills in Children with Attention-Deficit/Hyperactivity Disorder.
    Journal of child and adolescent psychopharmacology, 2017, Volume: 27, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Central Nervous Sys

2017
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2013, Volume: 52, Issue:12

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D

2013
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2013, Volume: 52, Issue:12

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D

2013
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2013, Volume: 52, Issue:12

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D

2013
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2013, Volume: 52, Issue:12

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D

2013
Methylphenidate ameliorates depressive comorbidity in ADHD children without any modification on differences in serum melatonin concentration between ADHD subtypes.
    International journal of molecular sciences, 2014, Sep-25, Volume: 15, Issue:9

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2014
Effects of behavioral and pharmacological therapies on peer reinforcement of deviancy in children with ADHD-only, ADHD and conduct problems, and controls.
    Journal of consulting and clinical psychology, 2015, Volume: 83, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Central Nervous System Stimulants;

2015
Factor structure of the restricted academic situation scale: implications for ADHD.
    Journal of attention disorders, 2009, Volume: 12, Issue:5

    Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity;

2009
Social information processing in elementary-school aged children with ADHD: medication effects and comparisons with typical children.
    Journal of abnormal child psychology, 2009, Volume: 37, Issue:4

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2009
Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy.
    The American journal of psychiatry, 2009, Volume: 166, Issue:12

    Topics: Adolescent; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorders; Atten

2009
Clinical response to methylphenidate in children diagnosed with attention-deficit hyperactivity disorder and comorbid psychiatric disorders.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2010, Volume: 55, Issue:5

    Topics: Anxiety Disorders; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder w

2010
Stimulant-responsive and stimulant-refractory aggressive behavior among children with ADHD.
    Pediatrics, 2010, Volume: 126, Issue:4

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimul

2010
Predictors of treatment response in adolescents with comorbid substance use disorder and attention-deficit/hyperactivity disorder.
    Journal of substance abuse treatment, 2013, Volume: 44, Issue:2

    Topics: Administration, Oral; Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; C

2013
A randomized controlled trial of clonidine added to psychostimulant medication for hyperactive and aggressive children.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:8

    Topics: Adolescent; Aggression; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disor

2003
Self-handicapping prior to academic-oriented tasks in children with attention deficit/hyperactivity disorder (ADHD): medication effects and comparisons with controls.
    Journal of abnormal child psychology, 2007, Volume: 35, Issue:2

    Topics: Adolescent; Aptitude; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorde

2007
Quetiapine addition in methylphenidate treatment-resistant adolescents with comorbid ADHD, conduct/oppositional-defiant disorder, and aggression: a prospective, open-label study.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:3

    Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central

2007
Long-acting methylphenidate has an effect on aggressive behavior in children with attention-deficit/hyperactivity disorder.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:4

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimul

2007
Switching from methylphenidate immediate release to MPH-SODAS in attention-deficit/hyperactivity disorder.
    European child & adolescent psychiatry, 2008, Volume: 17, Issue:3

    Topics: Administration, Oral; Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit

2008
Long-term follow-up of children with mental retardation/borderline intellectual functioning and ADHD.
    Journal of abnormal child psychology, 1997, Volume: 25, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

1997
Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder.
    Archives of general psychiatry, 1997, Volume: 54, Issue:12

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; Conduct D

1997
Methylphenidate and behavior modification in children with ADHD and comorbid ODD or CD: main and incremental effects across settings.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1999, Volume: 38, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Central Nervous System

1999
A pilot study of methylphenidate, clonidine, or the combination in ADHD comorbid with aggressive oppositional defiant or conduct disorder.
    Clinical pediatrics, 2000, Volume: 39, Issue:1

    Topics: Adolescent; Adrenergic alpha-Agonists; Aggression; Attention Deficit Disorder with Hyperactivity; Ce

2000

Other Studies

17 other studies available for methylphenidate and Conduct Disorder

ArticleYear
Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH.
    Epidemiology and psychiatric sciences, 2021, Feb-15, Volume: 30

    Topics: Accidents, Traffic; Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Defic

2021
Tardive Oculogyric Crisis With Low-Dose Antipsychotic in an Adolescent: A Case Report.
    The primary care companion for CNS disorders, 2018, Nov-22, Volume: 20, Issue:6

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys

2018
Does Methylphenidate Normalize Brain Dysfunction During Fear Learning in Adolescents With Disruptive Behavior Disorders?
    Journal of the American Academy of Child and Adolescent Psychiatry, 2018, Volume: 57, Issue:12

    Topics: Adolescent; Adult; Attention Deficit and Disruptive Behavior Disorders; Brain; Child; Conduct Disord

2018
Methylphenidate administration promotes sociability and reduces aggression in a mouse model of callousness.
    Psychopharmacology, 2019, Volume: 236, Issue:9

    Topics: Aggression; Animals; Attention; Conduct Disorder; Disease Models, Animal; Dopamine Uptake Inhibitors

2019
ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - a naturalistic long-term follow-up study.
    Addictive behaviors, 2014, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Attention Deficit Disorder with Hyperactivity; Central N

2014
Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:3

    Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp

2014
Methylphenidate-risperidone combination in child psychiatry: A retrospective analysis of 44 cases.
    Annales pharmaceutiques francaises, 2014, Volume: 72, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Psychiatry; Conduct Disorder

2014
Acute effects of methylphenidate on impulsivity and attentional behavior among adolescents comorbid for ADHD and conduct disorder.
    Journal of adolescence, 2016, Volume: 53

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimula

2016
Effect of Methylphenidate on Emotional Dysregulation in Children With Attention-Deficit/Hyperactivity Disorder + Oppositional Defiant Disorder/Conduct Disorder.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:2

    Topics: Adolescent; Affective Symptoms; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; C

2017
[Bipolar disorders as co-morbidity in childhood and adolescence--underdiagnosed or overinterpreted? Therapy of a 14-year-old boy with hyperkinetic conduct disorder and hypomania].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2010, Volume: 38, Issue:2

    Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; A

2010
No beneficial effects of adding parent training to methylphenidate treatment for ADHD + ODD/CD children: a 1-year prospective follow-up study.
    Journal of attention disorders, 2014, Volume: 18, Issue:2

    Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Conduct Diso

2014
Action of methyl-phenidylacetate (ritalin) and reserpine in behavior disorders in children and adults.
    The American journal of psychiatry, 1958, Volume: 115, Issue:4

    Topics: Behavior; Conduct Disorder; Mental Disorders; Methylphenidate; Reserpine

1958
BEHAVIOR DISORDERS OF CHILDREN WITH CEREBRAL DYSRHYTHMIAS; SUCCESSFUL TREATMENT OF SUBCONVULSIVE DYSRHYTHMIA WITH ANTICONVULSANTS.
    Archives of general psychiatry, 1964, Volume: 11

    Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Child; Child Behavior Disorders; Conduct

1964
European clinical guidelines for hyperkinetic disorder -- first upgrade.
    European child & adolescent psychiatry, 2004, Volume: 13 Suppl 1

    Topics: Alleles; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Ch

2004
Effects of combined treatment on Turkish children diagnosed with attention-deficit/hyperactivity disorder: a preliminary report.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:2

    Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Conduct Diso

2005
Risperidone-to-methylphenidate switch reaction in children: three cases.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:2

    Topics: Adolescent; Akathisia, Drug-Induced; Antipsychotic Agents; Attention Deficit and Disruptive Behavior

2007
Development and validation of the outburst monitoring scale for children and adolescents.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:4

    Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Central

2007