Page last updated: 2024-10-31

methylphenidate and Complications, Pregnancy

methylphenidate has been researched along with Complications, Pregnancy in 16 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"To report the effects of intravenous abuse of pentazocine hydrochloride and methylphenidate hydrochloride during pregnancy."7.68Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome. ( Casiro, OG; Debooy, VD; Seshia, MM; Tenenbein, M, 1993)
"Methylphenidate is a central nervous system stimulant medicinally used in the treatment of attention-deficit disorder with or without hyperactivity (ADD/ADHD)."5.43Methylphenidate in Pregnancy: A Multicenter, Prospective, Comparative, Observational Study. ( Arnon, J; Beck, E; Borisch, C; Bozzo, P; Diav-Citrin, O; Nulman, I; Ornoy, A; Richardson, JL; Shechtman, S; Wajnberg, R, 2016)
" Women who received amphetamine-dextroamphetamine or methylphenidate monotherapy in the first half of pregnancy were compared with unexposed women."3.85Placental Complications Associated With Psychostimulant Use in Pregnancy. ( Bateman, BT; Cohen, JM; Desai, RJ; Gray, KJ; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Park, Y; Patorno, E, 2017)
"To report the effects of intravenous abuse of pentazocine hydrochloride and methylphenidate hydrochloride during pregnancy."3.68Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome. ( Casiro, OG; Debooy, VD; Seshia, MM; Tenenbein, M, 1993)
"Methylphenidate is a centrally acting sympathomimetic used for the treatment of attention deficit/hyperactivity disorder in children and adolescents and for narcolepsy in adults."2.49First trimester in utero exposure to methylphenidate. ( Aagaard, L; Damkier, P; Dideriksen, D; Hallas, J; Pottegård, A, 2013)
"Methylphenidate is a central nervous system stimulant medicinally used in the treatment of attention-deficit disorder with or without hyperactivity (ADD/ADHD)."1.43Methylphenidate in Pregnancy: A Multicenter, Prospective, Comparative, Observational Study. ( Arnon, J; Beck, E; Borisch, C; Bozzo, P; Diav-Citrin, O; Nulman, I; Ornoy, A; Richardson, JL; Shechtman, S; Wajnberg, R, 2016)
"The granulomas are associated with a history of intravenous injection of medications (Ritalin and Talwin) intended for oral use."1.27Maternal death associated with intravenous methylphenidate (Ritalin) and pentazocine (Talwin) abuse. ( Edland, JF; Lundquest, DE; Young, WK, 1987)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cohen, JM1
Hernández-Díaz, S2
Bateman, BT2
Park, Y1
Desai, RJ1
Gray, KJ1
Patorno, E1
Mogun, H2
Huybrechts, KF2
Bröms, G1
Christensen, LB1
Einarsdóttir, K1
Engeland, A1
Furu, K1
Gissler, M1
Karlsson, P1
Karlstad, Ø1
Kieler, H1
Lahesmaa-Korpinen, AM1
Nørgaard, M1
Reutfors, J1
Sørensen, HT1
Zoega, H1
Poulton, AS1
Armstrong, B1
Nanan, RK1
Baker, AS1
Freeman, MP1
Jiang, HY1
Zhang, X1
Jiang, CM1
Fu, HB1
Zubedat, S1
Aga-Mizrachi, S1
Cymerblit-Sabba, A1
Ritter, A1
Nachmani, M1
Avital, A1
Diav-Citrin, O1
Shechtman, S1
Arnon, J1
Wajnberg, R1
Borisch, C1
Beck, E1
Richardson, JL1
Bozzo, P1
Nulman, I1
Ornoy, A1
Dideriksen, D1
Pottegård, A1
Hallas, J1
Aagaard, L1
Damkier, P1
BRET, AJ1
SIMON, S1
Humphreys, C1
Garcia-Bournissen, F1
Ito, S1
Koren, G1
Debooy, VD1
Seshia, MM1
Tenenbein, M1
Casiro, OG1
Loney, J1
Prinz, RJ1
Mishalow, J1
Joad, J1
Denson, R1
Nanson, JL1
McWatters, MA1
Lundquest, DE1
Young, WK1
Edland, JF1
O'Malley, JE1
Eisenberg, L1
Rapoport, JL1
Quinn, PO1
Lamprecht, F1

Reviews

4 reviews available for methylphenidate and Complications, Pregnancy

ArticleYear
Management of Attention Deficit Hyperactivity Disorder During Pregnancy.
    Obstetrics and gynecology clinics of North America, 2018, Volume: 45, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cognitive B

2018
Maternal and neonatal outcomes after exposure to ADHD medication during pregnancy: A systematic review and meta-analysis.
    Pharmacoepidemiology and drug safety, 2019, Volume: 28, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cohort Studies; Fe

2019
First trimester in utero exposure to methylphenidate.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 112, Issue:2

    Topics: Adult; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Fe

2013
Exposure to attention deficit hyperactivity disorder medications during pregnancy.
    Canadian family physician Medecin de famille canadien, 2007, Volume: 53, Issue:7

    Topics: Abnormalities, Drug-Induced; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivit

2007

Other Studies

12 other studies available for methylphenidate and Complications, Pregnancy

ArticleYear
Placental Complications Associated With Psychostimulant Use in Pregnancy.
    Obstetrics and gynecology, 2017, Volume: 130, Issue:6

    Topics: Abruptio Placentae; Adrenergic Uptake Inhibitors; Adult; Amphetamine; Atomoxetine Hydrochloride; Att

2017
Association Between Methylphenidate and Amphetamine Use in Pregnancy and Risk of Congenital Malformations: A Cohort Study From the International Pregnancy Safety Study Consortium.
    JAMA psychiatry, 2018, 02-01, Volume: 75, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amphetamine; Attention Deficit Disorder with Hyperac

2018
Perinatal Outcomes of Women Diagnosed with Attention-Deficit/Hyperactivity Disorder: An Australian Population-Based Cohort Study.
    CNS drugs, 2018, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Australia; Central Nervous System

2018
Methylphenidate and environmental enrichment ameliorate the deleterious effects of prenatal stress on attention functioning.
    Stress (Amsterdam, Netherlands), 2015, Volume: 18, Issue:3

    Topics: Animals; Anxiety; Attention; Behavior, Animal; Central Nervous System Stimulants; Environment; Femal

2015
Methylphenidate in Pregnancy: A Multicenter, Prospective, Comparative, Observational Study.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:9

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Cardiovascular Abnormalities;

2016
[Obesity in pregnancy. Trial of RP 8228. 1-Phenyl-1-(2-piperidyl)-1-acetoxymethane HCi. Threolevogyric form].
    Revue francaise de gynecologie et d'obstetrique, 1963, Volume: 58

    Topics: Female; Humans; Methylphenidate; Obesity; Pregnancy; Pregnancy Complications

1963
Intravenous pentazocine and methylphenidate abuse during pregnancy. Maternal lifestyle and infant outcome.
    American journal of diseases of children (1960), 1993, Volume: 147, Issue:10

    Topics: Adolescent; Adult; Developmental Disabilities; Female; Fetal Growth Retardation; Follow-Up Studies;

1993
Hyperkinetic/aggressive boys in treatment: predictors of clinical response to methylphenidate.
    The American journal of psychiatry, 1978, Volume: 135, Issue:12

    Topics: Age Factors; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Fem

1978
Hyperkinesis and maternal smoking.
    Canadian Psychiatric Association journal, 1975, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Hyperkinesis; Male; Methylphenidate; Pre

1975
Maternal death associated with intravenous methylphenidate (Ritalin) and pentazocine (Talwin) abuse.
    Journal of forensic sciences, 1987, Volume: 32, Issue:3

    Topics: Adult; Dextropropoxyphene; Female; Granuloma; Humans; Liver; Lung; Methylphenidate; Myocardium; Pent

1987
The hyperkinetic syndrome.
    Seminars in psychiatry, 1973, Volume: 5, Issue:1

    Topics: Birth Order; Child; Child Behavior Disorders; Child, Preschool; Dextroamphetamine; Female; Humans; H

1973
Minor physical anomalies and plasma dopamine-beta-hydroxylase activity in hyperactive boys.
    The American journal of psychiatry, 1974, Volume: 131, Issue:4

    Topics: Abnormalities, Multiple; Child; Dopamine beta-Hydroxylase; Female; Humans; Hyperkinesis; Imipramine;

1974