methylphenidate has been researched along with Chromosome-Defective Micronuclei in 4 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zamora-Perez, AL | 1 |
| Lazalde-Ramos, BP | 1 |
| Sosa-Macías, MG | 1 |
| Gómez-Meda, BC | 1 |
| Torres-Bugarín, O | 1 |
| Zúñiga-González, GM | 1 |
| Preston, RJ | 1 |
| Kollins, SH | 1 |
| Swanson, JM | 1 |
| Greenhill, LL | 1 |
| Wigal, T | 1 |
| Elliott, GR | 1 |
| Vitiello, B | 1 |
| El-Zein, RA | 1 |
| Abdel-Rahman, SZ | 1 |
| Hay, MJ | 1 |
| Lopez, MS | 1 |
| Bondy, ML | 1 |
| Morris, DL | 1 |
| Legator, MS | 1 |
| Jacobson-Kram, D | 1 |
| Mattison, D | 1 |
| Shelby, M | 1 |
| Slikker, W | 1 |
| Tice, R | 1 |
| Witt, K | 1 |
1 trial available for methylphenidate and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Cytogenetic effects in children treated with methylphenidate.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Pres | 2005 |
3 other studies available for methylphenidate and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Methylphenidate lacks genotoxic effects in mouse peripheral blood erythrocytes.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Erythrocytes; Male; Methylphenidate | 2011 |
Comments on 'Cytogenetic effects in children treated with methylphenidate' by El-Zein et al.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Chromosome | 2005 |
Methylphenidate and chromosome damage.
Topics: Adolescent; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulant | 2008 |