methylphenidate has been researched along with Chorea in 6 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a child with minimal brain dysfunction, we found that chorea was related to the major central effect of methylphenidate and probably to the effect of the drug on central catecholaminergic systems." | 7.66 | Methylphenidate-induced chorea: case report and pharmacologic implications. ( Klawans, HL; Nausieda, PA; Weiner, WJ, 1978) |
| " The studies reported 22 different treatments for chorea, including carbidopa/levodopa, tetrabenazine, clonazepam, methylphenidate, carbamazepine, topiramate, trihexyphenidyl, haloperidol, propranolol, risperidone, and valproate." | 5.41 | Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series. ( Bachoud-Lévi, AC; Blasco-Amaro, JA; Capuano, A; Isabel-Gómez, R; Martín-Gómez, C; Nou-Fontanet, L; Ortigoza-Escobar, JD; Zorzi, G, 2023) |
| "In a child with minimal brain dysfunction, we found that chorea was related to the major central effect of methylphenidate and probably to the effect of the drug on central catecholaminergic systems." | 3.66 | Methylphenidate-induced chorea: case report and pharmacologic implications. ( Klawans, HL; Nausieda, PA; Weiner, WJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Nou-Fontanet, L | 1 |
| Martín-Gómez, C | 1 |
| Isabel-Gómez, R | 1 |
| Bachoud-Lévi, AC | 1 |
| Zorzi, G | 1 |
| Capuano, A | 1 |
| Blasco-Amaro, JA | 1 |
| Ortigoza-Escobar, JD | 1 |
| Gauquelin, L | 1 |
| Tran, LT | 1 |
| Chouinard, S | 1 |
| Bernard, G | 1 |
| Machado, A | 1 |
| Cerqueira, J | 1 |
| Rodrigues, M | 1 |
| Soares-Fernandes, J | 1 |
| Morgan, JC | 1 |
| Winter, WC | 1 |
| Wooten, GF | 1 |
| Boogerd, W | 1 |
| Beijnen, JH | 1 |
| Weiner, WJ | 1 |
| Nausieda, PA | 1 |
| Klawans, HL | 1 |
1 review available for methylphenidate and Chorea
| Article | Year |
|---|---|
Systematic review of drug therapy for chorea in NXK2-1-related disorders: Efficacy and safety evidence from case studies and series.
Topics: Carbidopa; Chorea; Clonazepam; Humans; Levodopa; Methylphenidate; Tetrabenazine | 2023 |
5 other studies available for methylphenidate and Chorea
| Article | Year |
|---|---|
The Movement Disorder of Brain-Lung-Thyroid Syndrome Can be Responsive to Methylphenidate.
Topics: Athetosis; Central Nervous System Stimulants; Child; Chorea; Congenital Hypothyroidism; Female; Huma | 2017 |
Is methylphenidate-induced chorea responsive to chlorpromazine?
Topics: Child; Chlorpromazine; Chorea; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Humans; Met | 2010 |
Amphetamine-induced chorea in attention deficit-hyperactivity disorder.
Topics: Adult; Amphetamines; Attention Deficit Disorder with Hyperactivity; Chorea; Humans; Male; Methylphen | 2004 |
Methylphenidate for cerebral palsy with choreoathetosis.
Topics: Adrenergic Agents; Cerebral Palsy; Chorea; Dystonia; Humans; Methylphenidate; Muscle Spasticity | 2000 |
Methylphenidate-induced chorea: case report and pharmacologic implications.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Child; Child, Preschool; Chorea; Dopa | 1978 |