methylphenidate has been researched along with Cerebrovascular Disorders in 16 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 76-year-old male with poststroke depression, seizure disorder, and global aphasia improved markedly when treated with methylphenidate." | 7.69 | Methylphenidate treatment of poststroke depression in a patient with global aphasia. ( Chaudhary, P; Masand, P, 1994) |
| "A 76-year-old male with poststroke depression, seizure disorder, and global aphasia improved markedly when treated with methylphenidate." | 3.69 | Methylphenidate treatment of poststroke depression in a patient with global aphasia. ( Chaudhary, P; Masand, P, 1994) |
| "Methylphenidate provides a safe and effective alternative to tricyclic antidepressants in medically ill populations but appears to be less effective in the presence of delirium." | 3.68 | Methylphenidate in depressed medically ill patients. ( Ahmed, I; Hurwitz, S; Rosenberg, PB, 1991) |
| "Methylphenidate appears to be a safe and effective intervention in early poststroke rehabilitation that may expedite recovery." | 2.69 | Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study. ( Blackwell, B; Chrostowski, J; Grade, C; Redford, B; Toussaint, L, 1998) |
| "2 years) meeting DSM-III-R criteria for major depression were followed-up during a 3-week efficacy and side effect trial involving methylphenidate." | 2.67 | Efficacy and side effects of methylphenidate for poststroke depression. ( Abassian, M; Fawcett, J; Groves, L; Hartman, C; Kartan, U; Lazarus, LW; Lingam, VR; Neyman, I; Winemiller, DR, 1992) |
| "A minority of alcohol abusers develop severe cerebral dysfunction in the form of Wernicke-Korsakoff syndrome." | 2.35 | Chronic cerebral effects of alcohol and drug abuse. ( Grant, I; Mohns, L, 1975) |
| "Methylphenidate was superior to no drug treatment." | 1.30 | Neuropharmacologic treatment of hemineglect: a case report comparing bromocriptine and methylphenidate. ( Hurford, P; Jann, B; Stringer, AY, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kraut, AA | 1 |
| Langner, I | 1 |
| Lindemann, C | 1 |
| Banaschewski, T | 1 |
| Petermann, U | 1 |
| Petermann, F | 1 |
| Mikolajczyk, RT | 1 |
| Garbe, E | 1 |
| ROBERTS, HJ | 1 |
| Masand, P | 2 |
| Chaudhary, P | 1 |
| Murray, GB | 1 |
| Pickett, P | 1 |
| Masand, PS | 1 |
| Lazarus, LW | 3 |
| Moberg, PJ | 1 |
| Langsley, PR | 1 |
| Lingam, VR | 3 |
| Hurford, P | 1 |
| Stringer, AY | 1 |
| Jann, B | 1 |
| Grade, C | 1 |
| Redford, B | 1 |
| Chrostowski, J | 1 |
| Toussaint, L | 1 |
| Blackwell, B | 1 |
| Grant, I | 1 |
| Mohns, L | 1 |
| Winemiller, DR | 1 |
| Neyman, I | 1 |
| Hartman, C | 1 |
| Abassian, M | 1 |
| Kartan, U | 1 |
| Groves, L | 2 |
| Fawcett, J | 1 |
| Johnson, ML | 1 |
| Roberts, MD | 1 |
| Ross, AR | 1 |
| Witten, CM | 1 |
| Rosenberg, PB | 1 |
| Ahmed, I | 1 |
| Hurwitz, S | 1 |
| Oh, SH | 1 |
| Patel, AN | 1 |
| Bennett, HD | 1 |
| Meyer, JS | 1 |
| Eadie, GA | 1 |
| Ericsson, AD | 1 |
| Hoobler, SW | 1 |
| MacMahon, HR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Placebo-controlled Trial of Methylphenidate in Veterans With a Diagnosis of Post Traumatic Stress Disorder and Recent Cerebral Stroke.[NCT04885257] | Phase 2 | 60 participants (Anticipated) | Interventional | 2022-01-14 | Recruiting | ||
| Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475] | Phase 4 | 39 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methylphenidate and Cerebrovascular Disorders
| Article | Year |
|---|---|
Chronic cerebral effects of alcohol and drug abuse.
Topics: Alcoholism; Amphetamines; Barbiturates; Brain Diseases; Cannabis; Cerebrovascular Disorders; Cocaine | 1975 |
5 trials available for methylphenidate and Cerebrovascular Disorders
| Article | Year |
|---|---|
Psychostimulants in post-stroke depression.
Topics: Aged; Aged, 80 and over; Central Nervous System Stimulants; Cerebrovascular Disorders; Depressive Di | 1991 |
Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study.
Topics: Activities of Daily Living; Adaptation, Psychological; Aged; Central Nervous System Stimulants; Cere | 1998 |
Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study.
Topics: Activities of Daily Living; Adaptation, Psychological; Aged; Central Nervous System Stimulants; Cere | 1998 |
Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study.
Topics: Activities of Daily Living; Adaptation, Psychological; Aged; Central Nervous System Stimulants; Cere | 1998 |
Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study.
Topics: Activities of Daily Living; Adaptation, Psychological; Aged; Central Nervous System Stimulants; Cere | 1998 |
Efficacy and side effects of methylphenidate for poststroke depression.
Topics: Age Factors; Aged; Cerebrovascular Disorders; Depressive Disorder; Female; Follow-Up Studies; Humans | 1992 |
Methylphenidate in stroke patients with depression.
Topics: Aged; Aged, 80 and over; Cerebrovascular Disorders; Depressive Disorder; Female; Humans; Male; Methy | 1992 |
A pilot study of antihypertensive therapy in cerebrovascular disease.
Topics: Adult; Cerebrovascular Disorders; Clinical Trials as Topic; Depression; Female; Humans; Hypertension | 1967 |
10 other studies available for methylphenidate and Cerebrovascular Disorders
| Article | Year |
|---|---|
Comorbidities in ADHD children treated with methylphenidate: a database study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Cardiovascular Diseases; Case-Control Stu | 2013 |
THE SYNDROME OF NARCOLEPSY AND DIABETOGENIC ("FUNCTIONAL") HYPERINSULINISM, WITH SPECIAL REFERENCE TO OBESITY, DIABETES, IDIOPATHIC EDEMA, CEREBRAL DYSRHYTHMIAS AND MULTIPLE SCLEROSIS (200 PATIENTS).
Topics: Alcoholism; Arrhythmias, Cardiac; Cerebrovascular Disorders; Diabetes Mellitus; Drug Therapy; Edema; | 1964 |
Methylphenidate treatment of poststroke depression in a patient with global aphasia.
Topics: Aged; Aphasia; Cerebrovascular Disorders; Depressive Disorder; Dose-Response Relationship, Drug; Dru | 1994 |
Psychostimulants, poststroke depression, and side effects.
Topics: Age Factors; Aged; Antidepressive Agents; Central Nervous System Stimulants; Cerebrovascular Disorde | 1993 |
Methylphenidate and nortriptyline in the treatment of poststroke depression: a retrospective comparison.
Topics: Aged; Cerebrovascular Disorders; Depressive Disorder; Drug Monitoring; Female; Humans; Male; Methylp | 1994 |
Neuropharmacologic treatment of hemineglect: a case report comparing bromocriptine and methylphenidate.
Topics: Brain Damage, Chronic; Bromocriptine; Cerebrovascular Disorders; Dopamine Agents; Humans; Male; Meth | 1998 |
Methylphenidate in depressed medically ill patients.
Topics: Adjustment Disorders; Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Clinical Trials as | 1991 |
Methylphenidate in treating poststroke depression.
Topics: Aged; Cerebrovascular Disorders; Depressive Disorder; Female; Humans; Male; Methylphenidate; Retrosp | 1988 |
Self-inflicted strokes.
Topics: Amphetamine; Animals; Cerebral Angiography; Cerebrovascular Disorders; Fundus Oculi; Haplorhini; Hum | 1972 |
The management of massive gastrointestinal bleeding in the aged patient.
Topics: Aged; Blood Volume Determination; Cardiovascular Diseases; Cerebrovascular Disorders; Chromium Isoto | 1967 |