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methylphenidate and Cerebral Palsy

methylphenidate has been researched along with Cerebral Palsy in 6 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"High- and low-dose methylphenidate administration was evaluated prospectively for 3 elementary school-age children with cerebral palsy, cognitive impairments, and attention-deficit hyperactivity disorder (ADHD) symptoms using single-case, randomized, double-blind, placebo-controlled designs."9.12The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis. ( Hoch, J; Kim, O; Symons, FJ; Tervo, RC, 2007)
"Our objective was to study the short-term efficacy and safety of methylphenidate in patients with the dual diagnosis of cerebral palsy and attention-deficit hyperactivity disorder (ADHD)."9.10Efficacy of methylphenidate in patients with cerebral palsy and attention-deficit hyperactivity disorder (ADHD). ( Badihi, N; Gross-Tsur, V; Manor, O; Shalev, RS, 2002)
"High- and low-dose methylphenidate administration was evaluated prospectively for 3 elementary school-age children with cerebral palsy, cognitive impairments, and attention-deficit hyperactivity disorder (ADHD) symptoms using single-case, randomized, double-blind, placebo-controlled designs."5.12The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis. ( Hoch, J; Kim, O; Symons, FJ; Tervo, RC, 2007)
"Our objective was to study the short-term efficacy and safety of methylphenidate in patients with the dual diagnosis of cerebral palsy and attention-deficit hyperactivity disorder (ADHD)."5.10Efficacy of methylphenidate in patients with cerebral palsy and attention-deficit hyperactivity disorder (ADHD). ( Badihi, N; Gross-Tsur, V; Manor, O; Shalev, RS, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gross-Tsur, V2
Shalev, RS2
Badihi, N1
Manor, O1
Joseph, A1
Symons, FJ1
Tervo, RC1
Kim, O1
Hoch, J1
Boogerd, W1
Beijnen, JH1
Leary, PM1
Arens, L1
Marshall, S1
Schadle, S1
Schain, RJ1

Reviews

1 review available for methylphenidate and Cerebral Palsy

ArticleYear
Minimal brain Dysfunction.
    Current problems in pediatrics, 1975, Volume: 5, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child; Child, Prescho

1975

Trials

2 trials available for methylphenidate and Cerebral Palsy

ArticleYear
Efficacy of methylphenidate in patients with cerebral palsy and attention-deficit hyperactivity disorder (ADHD).
    Journal of child neurology, 2002, Volume: 17, Issue:12

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cerebr

2002
The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis.
    Journal of child neurology, 2007, Volume: 22, Issue:1

    Topics: Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; Cerebral Pal

2007

Other Studies

3 other studies available for methylphenidate and Cerebral Palsy

ArticleYear
Hallucinations during methylphenidate therapy.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity;

2004
Methylphenidate for cerebral palsy with choreoathetosis.
    Annals of internal medicine, 2000, Mar-21, Volume: 132, Issue:6

    Topics: Adrenergic Agents; Cerebral Palsy; Chorea; Dystonia; Humans; Methylphenidate; Muscle Spasticity

2000
Clinical experience with methylphenidate.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Mar-10, Volume: 55, Issue:10

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Cerebral Palsy; Child; Child, Preschool;

1979