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methylphenidate and Cardiovascular Stroke

methylphenidate has been researched along with Cardiovascular Stroke in 15 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"To investigate the association between use of methylphenidate and risk of myocardial infarction among Asians."8.02Association between methylphenidate and risk of myocardial infarction: A multinational self-controlled case series study. ( Chi, MH; Coghill, D; Hsieh, CY; Jeong, HE; Lai, EC; Lee, H; Liao, TC; Man, KKC; Shin, JY; Wong, ICK, 2021)
" In this short communication, we present a case of myocardial infarction in a male likely related to drug interactions between bupropion, erythromycin, and methylphenidate."7.73Acute myocardial infarction in a young male on methylphenidate, bupropion, and erythromycin. ( Awasthi, A; George, AK; Kunwar, AR, 2005)
"Methylphenidate (MPH) is an indirect-acting sympathomimetic drug and structurally related to amphetamine."5.72Acute myocardial infarction due to spontaneous coronary artery dissection in a 6-year-old boy with ADHD on the third day of treatment with methylphenidate. ( Becker, M; Kerst, G; Ostermayer, S; Pitzer, M; Pohlmann, U; Rascher, W; Stammschulte, T, 2022)
"Adult Attention Deficit Disorder is increasingly diagnosed and treated."5.36Acute myocardial infarction related to methylphenidate for adult attention deficit disorder. ( Thompson, J; Thompson, JR, 2010)
"To investigate the association between use of methylphenidate and risk of myocardial infarction among Asians."4.02Association between methylphenidate and risk of myocardial infarction: A multinational self-controlled case series study. ( Chi, MH; Coghill, D; Hsieh, CY; Jeong, HE; Lai, EC; Lee, H; Liao, TC; Man, KKC; Shin, JY; Wong, ICK, 2021)
" This case should be borne in mind before a diagnosis of myocardial infarction is given, or a decision to perform invasive coronary angiography is made in patients that use methylphenidate or related substances."3.80Myocardial injury in a 41-year-old male treated with methylphenidate: a case report. ( Hole, LD; Schjøtt, J, 2014)
" In this short communication, we present a case of myocardial infarction in a male likely related to drug interactions between bupropion, erythromycin, and methylphenidate."3.73Acute myocardial infarction in a young male on methylphenidate, bupropion, and erythromycin. ( Awasthi, A; George, AK; Kunwar, AR, 2005)
"Methylphenidate (MPH) is an indirect-acting sympathomimetic drug and structurally related to amphetamine."1.72Acute myocardial infarction due to spontaneous coronary artery dissection in a 6-year-old boy with ADHD on the third day of treatment with methylphenidate. ( Becker, M; Kerst, G; Ostermayer, S; Pitzer, M; Pohlmann, U; Rascher, W; Stammschulte, T, 2022)
"Methylphenidate is an important element of therapeutic strategies for ADHD."1.40[Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate]. ( Acquaviva, E; Bange, F; Delorme, R; Le Heuzey, MF; Mouren, MC, 2014)
" Dosage was inversely associated with risk."1.38Methylphenidate and risk of serious cardiovascular events in adults. ( Bilker, WB; Cziraky, MJ; Daniel, GW; Guevara, JP; Hennessy, S; Kimmel, SE; Newcomb, C; Schelleman, H; Strom, BL, 2012)
"Adult Attention Deficit Disorder is increasingly diagnosed and treated."1.36Acute myocardial infarction related to methylphenidate for adult attention deficit disorder. ( Thompson, J; Thompson, JR, 2010)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's10 (66.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Seeley, SL1
D'Souza, MS1
Stoops, TS1
Rorabaugh, BR1
Stammschulte, T1
Pitzer, M1
Rascher, W1
Becker, M1
Pohlmann, U1
Ostermayer, S1
Kerst, G1
Jeong, HE1
Lee, H1
Lai, EC1
Liao, TC1
Man, KKC1
Wong, ICK1
Coghill, D1
Chi, MH1
Hsieh, CY1
Shin, JY1
Bange, F1
Le Heuzey, MF1
Acquaviva, E1
Delorme, R1
Mouren, MC1
Hole, LD1
Schjøtt, J1
Hay, E1
Shklovski, V1
Blaer, Y1
Shlakhover, V1
Katz, A1
Wassef, N1
Khan, N1
Munir, S1
Hennessy, S2
Schelleman, H2
Daniel, GW2
Bilker, WB2
Kimmel, SE2
Guevara, J1
Cziraky, MJ2
Strom, BL2
Kratochvil, CJ1
Newcomb, C1
Guevara, JP1
Ruwald, MH1
Ruwald, AC1
Tønder, N1
Harbeck, C1
BRACHFELD, J1
MYERSON, RM1
George, AK1
Kunwar, AR1
Awasthi, A1
Thompson, J1
Thompson, JR1

Other Studies

15 other studies available for methylphenidate and Cardiovascular Stroke

ArticleYear
Short term methylphenidate treatment does not increase myocardial injury in the ischemic rat heart.
    Physiological research, 2020, 11-16, Volume: 69, Issue:5

    Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Drug Administration Schedule; Fe

2020
Acute myocardial infarction due to spontaneous coronary artery dissection in a 6-year-old boy with ADHD on the third day of treatment with methylphenidate.
    European child & adolescent psychiatry, 2022, Volume: 31, Issue:6

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Coronary Ve

2022
Association between methylphenidate and risk of myocardial infarction: A multinational self-controlled case series study.
    Pharmacoepidemiology and drug safety, 2021, Volume: 30, Issue:10

    Topics: Hong Kong; Humans; Methylphenidate; Myocardial Infarction; Prescriptions; Research Design

2021
[Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2014, Volume: 21, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; Ch

2014
Myocardial injury in a 41-year-old male treated with methylphenidate: a case report.
    BMC research notes, 2014, Jul-29, Volume: 7

    Topics: Adult; Chest Pain; Humans; Male; Methylphenidate; Myocardial Infarction; Tachycardia, Supraventricul

2014
Intravenous methylphenidate: an unusual way to provoke ST-elevation myocardial infarction.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:2

    Topics: Adult; Central Nervous System Stimulants; Electrocardiography; Emergency Service, Hospital; Heart; H

2015
Quetiapine-induced myocarditis presenting as acute STEMI.
    BMJ case reports, 2015, Jan-09, Volume: 2015

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; C

2015
Cardiovascular safety of ADHD medications: rationale for and design of an investigator-initiated observational study.
    Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Amphetamines; Atomoxetine Hydrochloride; Attention Deficit

2010
ADHD pharmacotherapy: rates of stimulant use and cardiovascular risk.
    The American journal of psychiatry, 2012, Volume: 169, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; De

2012
Methylphenidate and risk of serious cardiovascular events in adults.
    The American journal of psychiatry, 2012, Volume: 169, Issue:2

    Topics: Adult; Aged; Central Nervous System Stimulants; Cohort Studies; Databases, Factual; Death, Sudden, C

2012
[Methylphenidate induced ST elevation acute myocardial infarction].
    Ugeskrift for laeger, 2012, Mar-05, Volume: 174, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Coronary Vasospasm

2012
[Misleading case report of heart problems by methylphenidate].
    Ugeskrift for laeger, 2012, May-07, Volume: 174, Issue:19

    Topics: Central Nervous System Stimulants; Humans; Male; Methylphenidate; Myocardial Infarction

2012
TREATMENT OF CARDIOGENIC SHOCK AND VASOPRESSOR DEPENDENCY WITH INTRAVENOUS METHYLPHENIDATE (RITALIN).
    The American journal of cardiology, 1965, Volume: 15

    Topics: Cardiomegaly; Drug Therapy; Geriatrics; Heart Failure; Humans; Hypotension; Methylphenidate; Myocard

1965
Acute myocardial infarction in a young male on methylphenidate, bupropion, and erythromycin.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:4

    Topics: Adolescent; Anti-Bacterial Agents; Antidepressive Agents, Second-Generation; Bupropion; Central Nerv

2005
Acute myocardial infarction related to methylphenidate for adult attention deficit disorder.
    The Journal of emergency medicine, 2010, Volume: 38, Issue:1

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Coronary Va

2010