methylphenidate has been researched along with Cardiac Arrest, Sudden in 15 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate is an important element of therapeutic strategies for ADHD." | 1.40 | [Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate]. ( Acquaviva, E; Bange, F; Delorme, R; Le Heuzey, MF; Mouren, MC, 2014) |
| "Reports on sudden cardiac death (SCD) of children and adolescents treated with stimulant agents have raised concerns regarding the need for cardiovascular monitoring and risk stratification schedules." | 1.38 | Late potentials in the signal-averaged electrocardiogram in pre-pubertal children with ADHD, before and after methylphenidate treatment. ( Glazer, J; Golubchik, P; Imbar, S; Nahshoni, E; Sever, J; Shoval, G; Strasberg, B; Weizman, A; Zalsman, G, 2012) |
| " Dosage was inversely associated with risk." | 1.38 | Methylphenidate and risk of serious cardiovascular events in adults. ( Bilker, WB; Cziraky, MJ; Daniel, GW; Guevara, JP; Hennessy, S; Kimmel, SE; Newcomb, C; Schelleman, H; Strom, BL, 2012) |
| " Despite their efficacy and long history of use, there is concern about their potential for adverse cardiovascular effects in children and adolescents." | 1.36 | Cardiovascular safety of stimulant medications for pediatric attention-deficit hyperactivity disorder. ( Muniz, R; Silva, RR; Skimming, JW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bange, F | 1 |
| Le Heuzey, MF | 1 |
| Acquaviva, E | 1 |
| Delorme, R | 1 |
| Mouren, MC | 1 |
| Awudu, GA | 1 |
| Besag, FM | 1 |
| Banaschewski, T | 1 |
| Silva, RR | 1 |
| Skimming, JW | 1 |
| Muniz, R | 1 |
| Nahshoni, E | 1 |
| Golubchik, P | 1 |
| Glazer, J | 1 |
| Sever, J | 1 |
| Strasberg, B | 1 |
| Imbar, S | 1 |
| Shoval, G | 1 |
| Weizman, A | 1 |
| Zalsman, G | 1 |
| Batra, AS | 1 |
| Alexander, ME | 1 |
| Silka, MJ | 1 |
| Kratochvil, CJ | 1 |
| Schelleman, H | 1 |
| Bilker, WB | 1 |
| Kimmel, SE | 1 |
| Daniel, GW | 1 |
| Newcomb, C | 1 |
| Guevara, JP | 1 |
| Cziraky, MJ | 1 |
| Strom, BL | 1 |
| Hennessy, S | 1 |
| Langendijk, PN | 1 |
| Wilde, AA | 1 |
| Knight, M | 1 |
| Vitiello, B | 1 |
| Maloney, MJ | 1 |
| Schwam, JS | 1 |
3 reviews available for methylphenidate and Cardiac Arrest, Sudden
| Article | Year |
|---|---|
Cardiovascular effects of methylphenidate, amphetamines and atomoxetine in the treatment of attention-deficit hyperactivity disorder: an update.
Topics: Amphetamines; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressu | 2014 |
Attention-deficit/hyperactivity disorder, stimulant therapy, and the patient with congenital heart disease: evidence and reason.
Topics: Amphetamines; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Coro | 2012 |
Understanding the risk of using medications for attention deficit hyperactivity disorder with respect to physical growth and cardiovascular function.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Appetite; Atomoxetine Hydrochloride; Attention Deficit Dis | 2008 |
12 other studies available for methylphenidate and Cardiac Arrest, Sudden
| Article | Year |
|---|---|
[Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate].
Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; Ch | 2014 |
[Joint position of the Guideline Group of the European Network for Hyperkintetic Disorders (EUNETHYDIS) and the German Central ADHD Network for ECG Recording on methylphenidate prescriptions].
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Death, Sudd | 2008 |
Cardiovascular safety of stimulant medications for pediatric attention-deficit hyperactivity disorder.
Topics: Adolescent; Adult; Amphetamines; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Card | 2010 |
Late potentials in the signal-averaged electrocardiogram in pre-pubertal children with ADHD, before and after methylphenidate treatment.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2012 |
ADHD pharmacotherapy: rates of stimulant use and cardiovascular risk.
Topics: Attention Deficit Disorder with Hyperactivity; Blood Pressure; Central Nervous System Stimulants; De | 2012 |
Methylphenidate and risk of serious cardiovascular events in adults.
Topics: Adult; Aged; Central Nervous System Stimulants; Cohort Studies; Databases, Factual; Death, Sudden, C | 2012 |
Encouraging news about ADHD drugs and heart risk in adults.
Topics: Adult; Attention; Attention Deficit Disorder with Hyperactivity; Cardiovascular Diseases; Central Ne | 2012 |
Second FDA panel advises on stimulants.
Topics: Advisory Committees; Central Nervous System Stimulants; Death, Sudden, Cardiac; Drug Labeling; Hallu | 2006 |
[Medication for ADHD and the risk of cardiovascular mortality].
Topics: Amphetamine; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivity; Cardiovascular Dis | 2006 |
ADHD update: new data on the risks of medication.
Topics: Adrenergic Uptake Inhibitors; Adult; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hype | 2006 |
Stimulant-drug therapy for attention-deficit disorder (with or without hyperactivity) and sudden cardiac death.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Death, Sudd | 2007 |
Clonidine and sudden death.
Topics: Child; Clonidine; Death, Sudden, Cardiac; Drug Therapy, Combination; Female; Humans; Male; Methylphe | 1995 |