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methylphenidate and Cannabis Abuse

methylphenidate has been researched along with Cannabis Abuse in 11 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" Here, we challenged 48 participants (24 controls and 24 marijuana abusers) with methylphenidate (MP), a drug that elevates extracellular dopamine (DA) as a surrogate for probing the reactivity of the brain to DA stimulation."5.19Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity. ( Alexoff, D; Fowler, JS; Jayne, M; Logan, J; Telang, F; Tomasi, D; Volkow, ND; Wang, GJ; Wong, C, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Demiral, ŞB2
Tomasi, D3
Wiers, CE2
Manza, P1
Shokri-Kojori, E2
Studentsova, Y1
Wang, GJ3
Volkow, ND3
Looby, A1
De Young, KP1
Earleywine, M1
Telang, F1
Fowler, JS1
Alexoff, D1
Logan, J1
Jayne, M1
Wong, C1
Wong, CT1
Abi-Dargham, A1
Olivares, EL1
Kendler, KS1
Neale, MC1
Gillespie, NA1
Lile, JA1
Kelly, TH1
Pinsky, DJ1
Hays, LR1
Franke, AG1
Schwarze, CE1
Christmann, M1
Bonertz, C1
Hildt, E1
Lieb, K1
Pereira, RR1
van de Wetering, BJ1
Aharonovich, E1
Garawi, F1
Bisaga, A1
Brooks, D1
Raby, WN1
Rubin, E1
Nunes, EV1
Levin, FR1
Kollins, SH1
Durst, R1
Rebaudengo-Rosca, P1

Reviews

1 review available for methylphenidate and Cannabis Abuse

ArticleYear
ADHD, substance use disorders, and psychostimulant treatment: current literature and treatment guidelines.
    Journal of attention disorders, 2008, Volume: 12, Issue:2

    Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child

2008

Trials

4 trials available for methylphenidate and Cannabis Abuse

ArticleYear
Methylphenidate's effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:8

    Topics: Adult; Cerebellum; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Humans; Magnetic Resonan

2019
Challenging expectancies to prevent nonmedical prescription stimulant use: a randomized, controlled trial.
    Drug and alcohol dependence, 2013, Sep-01, Volume: 132, Issue:1-2

    Topics: Adolescent; Alcoholism; Central Nervous System Stimulants; Data Interpretation, Statistical; Female;

2013
Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-29, Volume: 111, Issue:30

    Topics: Adult; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Emotions; Female

2014
Concurrent cannabis use during treatment for comorbid ADHD and cocaine dependence: effects on outcome.
    The American journal of drug and alcohol abuse, 2006, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants;

2006

Other Studies

6 other studies available for methylphenidate and Cannabis Abuse

ArticleYear
Cannabis Abusers Show Hypofrontality and Blunted Brain Responses to a Stimulant Challenge in Females but not in Males.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:10

    Topics: Adult; Brain; Central Nervous System Stimulants; Female; Fluorodeoxyglucose F18; Humans; Image Proce

2016
The Genetic and Environmental Association Between Parental Monitoring and Risk of Cannabis, Stimulants, and Cocaine Initiation in a Sample of Male Twins: Does Parenting Matter?
    Twin research and human genetics : the official journal of the International Society for Twin Studies, 2016, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Child; Cocaine-Related Disorders; Humans; Male; Marijuana Abuse; Methylphenidate;

2016
Substitution profile of Delta9-tetrahydrocannabinol, triazolam, hydromorphone, and methylphenidate in humans discriminating Delta9-tetrahydrocannabinol.
    Psychopharmacology, 2009, Volume: 203, Issue:2

    Topics: Administration, Oral; Adult; Case-Control Studies; Discrimination, Psychological; Double-Blind Metho

2009
[Characteristics of university students using stimulants for cognitive enhancement: a pilot study].
    Psychiatrische Praxis, 2012, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Alcoholism; Amphetamines; Case-Control Studies; Central Nervous System Stimulants

2012
[Caffeine, cannabis and cocaine: from automedication to 'automutilation' in adults with ADHD].
    Nederlands tijdschrift voor geneeskunde, 2004, Dec-25, Volume: 148, Issue:52

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System Stimulants; C

2004
[Attention deficit hyperactivity disorder, facilitating alcohol and drug abuse in an adult].
    Harefuah, 1997, May-01, Volume: 132, Issue:9

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Cannabis; Central Nervous System S

1997