methylphenidate has been researched along with Brain Ischemia in 1 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral ischemia is the main cause of permanent adult disabilities worldwide." | 1.62 | Methylphenidate exerts neuroprotective effects through the AMPK signaling pathway. ( Huang, X; Huang, Y; Li, P; Yang, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, P | 1 |
| Huang, Y | 1 |
| Yang, Y | 1 |
| Huang, X | 1 |
1 other study available for methylphenidate and Brain Ischemia
| Article | Year |
|---|---|
Methylphenidate exerts neuroprotective effects through the AMPK signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Brain Ischemia; Cell Survival; Cells, Cultured; D | 2021 |