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methylphenidate and Brain Disorders

methylphenidate has been researched along with Brain Disorders in 13 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" Any long-term psychotropic treatment in childhood raises concerns about possible adverse neurological and psychiatric outcomes."2.61Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence. ( Ansari, MT; Banaschewski, T; Buitelaar, JK; Carucci, S; Coghill, D; Danckaerts, M; Dittmann, RW; Falissard, B; Garas, P; Groom, MJ; Hall, CL; Hollis, C; Inglis, SK; Kochhar, P; Konrad, K; Kovshoff, H; Krinzinger, H; Liddle, EB; McCarthy, S; Nagy, P; Neubert, A; Roberts, S; Sayal, K; Sonuga-Barke, E; Wong, ICK; Xia, J; Zuddas, A, 2019)
"A minority of alcohol abusers develop severe cerebral dysfunction in the form of Wernicke-Korsakoff syndrome."2.35Chronic cerebral effects of alcohol and drug abuse. ( Grant, I; Mohns, L, 1975)
"Bereavement after diagnosing AIDS or other HIV disease, psychological symptoms secondary to brain disease and the social consequences of having AIDS all interact to produce a devastating illness where the patient may be intensely grieving, demented and totally rejected by all of society."1.27Psychosocial aspects of AIDS. ( Goldmeier, D, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krinzinger, H1
Hall, CL1
Groom, MJ1
Ansari, MT1
Banaschewski, T1
Buitelaar, JK1
Carucci, S1
Coghill, D1
Danckaerts, M1
Dittmann, RW1
Falissard, B1
Garas, P1
Inglis, SK1
Kovshoff, H1
Kochhar, P1
McCarthy, S1
Nagy, P1
Neubert, A1
Roberts, S1
Sayal, K1
Sonuga-Barke, E1
Wong, ICK1
Xia, J1
Zuddas, A1
Hollis, C1
Konrad, K1
Liddle, EB1
Salavert, J1
Ramos-Quiroga, JA1
Moreno-Alcázar, A1
Caseras, X1
Palomar, G1
Radua, J1
Bosch, R1
Salvador, R1
McKenna, PJ1
Casas, M1
Pomarol-Clotet, E1
Pundir, M1
Nagarkar, AN1
Panda, NK1
Creager, RO1
VanRiper, C1
Denollet, J1
Grant, I1
Mohns, L1
Schain, RJ1
Nasrallah, HA1
Loney, J1
Olson, SC1
McCalley-Whitters, M1
Kramer, J1
Jacoby, CG1
Goldmeier, D1
Conners, CK1
Schwartz, ML1
Pizzo, SV1
McKee, PA1
Baldwin, RL1
Peters, JE1
Garrettson, LK1
Perel, JM1
Dayton, PG1

Reviews

4 reviews available for methylphenidate and Brain Disorders

ArticleYear
Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence.
    Neuroscience and biobehavioral reviews, 2019, Volume: 107

    Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Central Nervous System Stimulants; Hu

2019
[Biological backgrounds of the hyperkinetic syndrome].
    Tijdschrift voor kindergeneeskunde, 1983, Volume: 51, Issue:2

    Topics: Arousal; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Catecholamines; Cereb

1983
Chronic cerebral effects of alcohol and drug abuse.
    The International journal of the addictions, 1975, Volume: 10, Issue:5

    Topics: Alcoholism; Amphetamines; Barbiturates; Brain Diseases; Cannabis; Cerebrovascular Disorders; Cocaine

1975
Minimal brain Dysfunction.
    Current problems in pediatrics, 1975, Volume: 5, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child; Child, Prescho

1975

Trials

1 trial available for methylphenidate and Brain Disorders

ArticleYear
The effect of methylphenidate on the verbal productivity of children with cerebral dysfunction.
    Journal of speech and hearing research, 1967, Volume: 10, Issue:3

    Topics: Brain Diseases; Child; Female; Humans; Male; Methylphenidate; Placebos; Speech Disorders; Speech The

1967

Other Studies

8 other studies available for methylphenidate and Brain Disorders

ArticleYear
Functional Imaging Changes in the Medial Prefrontal Cortex in Adult ADHD.
    Journal of attention disorders, 2018, Volume: 22, Issue:7

    Topics: Adult; Attention; Attention Deficit Disorder with Hyperactivity; Brain Diseases; Brain Mapping; Cent

2018
Intervention strategies in children with cochlear implants having attention deficit hyperactivity disorder.
    International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:6

    Topics: Attention; Attention Deficit Disorder with Hyperactivity; Auditory Threshold; Brain Diseases; Centra

2007
Cortical atrophy in young adults with a history of hyperactivity in childhood.
    Psychiatry research, 1986, Volume: 17, Issue:3

    Topics: Adult; Atrophy; Attention Deficit Disorder with Hyperactivity; Brain; Brain Diseases; Cerebral Corte

1986
Psychosocial aspects of AIDS.
    British journal of hospital medicine, 1987, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Attitude to Health; Brain Diseases; Child; Dementia; Dextroamphe

1987
The effect of stimulant drugs on human figure drawings in children with minimal brain dysfunction.
    Psychopharmacologia, 1971, Volume: 19, Issue:4

    Topics: Art; Attention; Brain Diseases; Child; Dextroamphetamine; Female; Humans; Male; Methylphenidate; Pla

1971
Minimal brain dysfunction and methylphenidate.
    The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5

    Topics: Advertising; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Brain Diseases; C

1971
Hematologic complications from tranquilizers in children.
    Southern medical journal, 1968, Volume: 61, Issue:10

    Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Dise

1968
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
    JAMA, 1969, Mar-17, Volume: 207, Issue:11

    Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscou

1969