methylphenidate has been researched along with Bradykinesia in 2 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate improved gait hypokinesia and freezing in patients with advanced Parkinson's disease receiving subthalamic nucleus stimulation." | 2.77 | Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial. ( Azulay, JP; Bloem, BR; Bordet, R; Brefel-Courbon, C; Corvol, JC; Debû, B; Defebvre, L; Delval, A; Destée, A; Devos, D; Drapier, S; Duhamel, A; Dujardin, K; Durif, F; Eusebio, A; Faighel, M; Fraix, V; Giordana, C; Guehl, D; Houeto, JL; Lagha-Boukbiza, O; Maltête, D; Moreau, C; Ory-Magne, F; Petyt, G; Rascol, O; Sablonniere, B; Saulnier, PJ; Tison, F; Tranchant, C; Vidailhet, M; Vuillaume, I, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreau, C | 1 |
| Delval, A | 1 |
| Defebvre, L | 1 |
| Dujardin, K | 1 |
| Duhamel, A | 1 |
| Petyt, G | 1 |
| Vuillaume, I | 1 |
| Corvol, JC | 1 |
| Brefel-Courbon, C | 1 |
| Ory-Magne, F | 1 |
| Guehl, D | 1 |
| Eusebio, A | 1 |
| Fraix, V | 1 |
| Saulnier, PJ | 1 |
| Lagha-Boukbiza, O | 1 |
| Durif, F | 1 |
| Faighel, M | 1 |
| Giordana, C | 1 |
| Drapier, S | 1 |
| Maltête, D | 1 |
| Tranchant, C | 1 |
| Houeto, JL | 1 |
| Debû, B | 1 |
| Sablonniere, B | 1 |
| Azulay, JP | 1 |
| Tison, F | 1 |
| Rascol, O | 1 |
| Vidailhet, M | 1 |
| Destée, A | 1 |
| Bloem, BR | 1 |
| Bordet, R | 1 |
| Devos, D | 1 |
| Rodriguez-Oroz, MC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentric Trial[NCT00914095] | Phase 4 | 69 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methylphenidate and Bradykinesia
| Article | Year |
|---|---|
Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial.
Topics: Aged; Deep Brain Stimulation; Dopamine Uptake Inhibitors; Double-Blind Method; Female; France; Gait | 2012 |
1 other study available for methylphenidate and Bradykinesia
| Article | Year |
|---|---|
Methylphenidate for freezing of gait in Parkinson's disease.
Topics: Deep Brain Stimulation; Dopamine Uptake Inhibitors; Female; Gait Disorders, Neurologic; Humans; Hypo | 2012 |