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methylphenidate and Borderline Personality Disorder

methylphenidate has been researched along with Borderline Personality Disorder in 12 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Borderline Personality Disorder: A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)

Research Excerpts

ExcerptRelevanceReference
"Two patients with borderline personality disorder experienced dramatic dysphoric episodes after acute administration of intravenous methylphenidate in a double-blind manner."9.06Dysphoria associated with methylphenidate infusion in borderline personality disorder. ( Cowdry, RW; Gardner, DL; Lucas, PB; Wolkowitz, OM, 1987)
"Two patients with borderline personality disorder experienced dramatic dysphoric episodes after acute administration of intravenous methylphenidate in a double-blind manner."5.06Dysphoria associated with methylphenidate infusion in borderline personality disorder. ( Cowdry, RW; Gardner, DL; Lucas, PB; Wolkowitz, OM, 1987)
"A case is reported of a young woman with attention deficit disorder and concomitant borderline personality disorder who was successfully treated with methylphenidate."3.67Treatment of attention deficit and borderline personality disorders with psychostimulants: case report. ( Hooberman, D; Stern, TA, 1984)
"The diagnosis of attention deficit disorder, residual type, should be considered in patients with prominent complaints of impulsivity, restlessness, emotional lability, and hot temper who do not suffer from schizophrenia or major mood disorder and do not have symptoms of schizotypal or borderline personality disorders."2.66A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults. ( Reimherr, FW; Ward, M; Wender, PH; Wood, D, 1985)
"A subcategory of patients with borderline personality disorder (BPD) who also meet criteria for attention deficit disorder (ADD) has recently been described."1.27Use of imipramine for attention deficit disorder in a borderline patient. ( Denton, C; Satel, S; Southwick, S, 1988)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gvirts, HZ1
Lewis, YD1
Dvora, S1
Feffer, K1
Nitzan, U1
Carmel, Z1
Levkovitz, Y1
Maoz, H1
Prada, P1
Nicastro, R1
Zimmermann, J1
Hasler, R1
Aubry, JM1
Perroud, N1
Wolf, U1
Golombek, U1
Diefenbacher, A1
Golubchik, P1
Sever, J1
Zalsman, G1
Weizman, A1
Rogeness, GA1
Hernandez, JM1
Macedo, CA1
Mitchell, EL1
Amrung, SA1
Harris, WR1
Klar, H1
Siever, LJ1
Hooberman, D1
Stern, TA1
van Reekum, R1
Links, PS1
Satel, S1
Southwick, S1
Denton, C1
Robinson, D1
Bailine, S1
Lieberman, J1
Lucas, PB1
Gardner, DL1
Wolkowitz, OM1
Cowdry, RW1
Wender, PH1
Reimherr, FW1
Wood, D1
Ward, M1

Reviews

1 review available for methylphenidate and Borderline Personality Disorder

ArticleYear
The psychopharmacologic treatment of personality disorders.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Antisocial Personality Diso

1984

Trials

4 trials available for methylphenidate and Borderline Personality Disorder

ArticleYear
The effect of methylphenidate on decision making in patients with borderline personality disorder and attention-deficit/hyperactivity disorder.
    International clinical psychopharmacology, 2018, Volume: 33, Issue:4

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Central Nervo

2018
N of 1 study: methylphenidate in a patient with borderline personality disorder and attention deficit hyperactivity disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:3

    Topics: Adult; Attention; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Do

1994
Dysphoria associated with methylphenidate infusion in borderline personality disorder.
    The American journal of psychiatry, 1987, Volume: 144, Issue:12

    Topics: Adult; Affective Symptoms; Akathisia, Drug-Induced; Borderline Personality Disorder; Double-Blind Me

1987
A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults.
    The American journal of psychiatry, 1985, Volume: 142, Issue:5

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Clinical Tria

1985

Other Studies

7 other studies available for methylphenidate and Borderline Personality Disorder

ArticleYear
Addition of methylphenidate to intensive dialectical behaviour therapy for patients suffering from comorbid borderline personality disorder and ADHD: a naturalistic study.
    Attention deficit and hyperactivity disorders, 2015, Volume: 7, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Borderline Personality Disor

2015
[Diagnosis and treatment of the attention-deficit/hyperactivity syndrome (ADHS) in adults with drug addiction in in-patient and out-patient setting].
    Psychiatrische Praxis, 2006, Volume: 33, Issue:5

    Topics: Adult; Alcoholism; Ambulatory Care; Attention Deficit Disorder with Hyperactivity; Borderline Person

2006
Methylphenidate in the treatment of female adolescents with cooccurrence of attention deficit/hyperactivity disorder and borderline personality disorder: a preliminary open-label trial.
    International clinical psychopharmacology, 2008, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; C

2008
Clinical characteristics of emotionally disturbed boys with very low activities of dopamine-beta-hydroxylase.
    Journal of the American Academy of Child Psychiatry, 1984, Volume: 23, Issue:2

    Topics: Adolescent; Affective Symptoms; Antipsychotic Agents; Borderline Personality Disorder; Child; Child

1984
Treatment of attention deficit and borderline personality disorders with psychostimulants: case report.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:10

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Delayed-Actio

1984
Use of imipramine for attention deficit disorder in a borderline patient.
    The Journal of nervous and mental disease, 1988, Volume: 176, Issue:5

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Humans; Imipr

1988
Dysphoria associated with methylphenidate infusions.
    The American journal of psychiatry, 1988, Volume: 145, Issue:10

    Topics: Adult; Affective Symptoms; Arrhythmias, Cardiac; Borderline Personality Disorder; Humans; Methylphen

1988