methylphenidate has been researched along with Attention Deficit and Disruptive Behavioral Disorders in 83 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although the nonrandomized, nonblind design limits the conclusions of our exploratory study, our findings suggest that when ADHD is comorbid with ODD and aggression MPH and risperidone are both effective on aggressive behavior, but only stimulants are effective on ADHD symptoms." | 9.24 | A Naturalistic Comparison of Methylphenidate and Risperidone Monotherapy in Drug-Naive Youth With Attention-Deficit/Hyperactivity Disorder Comorbid With Oppositional Defiant Disorder and Aggression. ( Manfredi, A; Masi, G; Milone, A; Muratori, P; Nieri, G; Pfanner, C, 2017) |
| "High- and low-dose methylphenidate administration was evaluated prospectively for 3 elementary school-age children with cerebral palsy, cognitive impairments, and attention-deficit hyperactivity disorder (ADHD) symptoms using single-case, randomized, double-blind, placebo-controlled designs." | 9.12 | The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis. ( Hoch, J; Kim, O; Symons, FJ; Tervo, RC, 2007) |
| "We report a case of a girl with Attention deficit hyperactivity disorder (ADHD) and Oppositional defiant disorder (ODD) who experienced a 3-hour episode of nocturnal complex bizarre visual hallucinations when treated with 18 mg Osmotic Release Oral System (OROS) methylphenidate (MPH)." | 7.77 | Long lasting complex nocturnal hallucinations during Osmotic Release Oral System (OROS) methylphenidate treatment in a 7-year old girl. ( Goetz, M; Hrdlicka, M; Prihodova, I, 2011) |
| "Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score." | 5.40 | Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder. ( Bilgiç, A; Hergüner, S; Yılmaz, S, 2014) |
| "Although the nonrandomized, nonblind design limits the conclusions of our exploratory study, our findings suggest that when ADHD is comorbid with ODD and aggression MPH and risperidone are both effective on aggressive behavior, but only stimulants are effective on ADHD symptoms." | 5.24 | A Naturalistic Comparison of Methylphenidate and Risperidone Monotherapy in Drug-Naive Youth With Attention-Deficit/Hyperactivity Disorder Comorbid With Oppositional Defiant Disorder and Aggression. ( Manfredi, A; Masi, G; Milone, A; Muratori, P; Nieri, G; Pfanner, C, 2017) |
| "High- and low-dose methylphenidate administration was evaluated prospectively for 3 elementary school-age children with cerebral palsy, cognitive impairments, and attention-deficit hyperactivity disorder (ADHD) symptoms using single-case, randomized, double-blind, placebo-controlled designs." | 5.12 | The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis. ( Hoch, J; Kim, O; Symons, FJ; Tervo, RC, 2007) |
| "We report a case of a girl with Attention deficit hyperactivity disorder (ADHD) and Oppositional defiant disorder (ODD) who experienced a 3-hour episode of nocturnal complex bizarre visual hallucinations when treated with 18 mg Osmotic Release Oral System (OROS) methylphenidate (MPH)." | 3.77 | Long lasting complex nocturnal hallucinations during Osmotic Release Oral System (OROS) methylphenidate treatment in a 7-year old girl. ( Goetz, M; Hrdlicka, M; Prihodova, I, 2011) |
| "Participants with disruptive behavior disorder were randomized to receive a single dose of methylphenidate 0." | 2.87 | Effects of Methylphenidate During Fear Learning in Antisocial Adolescents: A Randomized Controlled fMRI Trial. ( Bet, P; Cohn, MD; Doreleijers, T; Pape, LE; Popma, A; van den Akker-Nijdam, ME; van den Brink, W; van Lith, K; van Loon, AWG; van Wingen, GA; Veltman, DJ, 2018) |
| "The Wender-Reimherr Adult Attention Deficit Disorder Scale (WRAADDS) measured outcome." | 2.75 | OROS methylphenidate in the treatment of adults with ADHD: a 6-month, open-label, follow-up study. ( Halls, C; Marchant, BK; Reimherr, FW; Strong, RE; Williams, ED, 2010) |
| " Children whose aggressive behavior persisted at the conclusion of the lead-in phase were randomly assigned to receive double-blind, flexibly dosed divalproex or a placebo adjunctive to stimulant for 8 weeks." | 2.74 | Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. ( Blader, JC; Jensen, PS; Kafantaris, V; Pliszka, SR; Schooler, NR, 2009) |
| "Differences in substance use were revealed in favor of the UCPP, with more adolescents in the CU group smoking cigarettes in the last month (UCPP 17%, CU 42%; chi2 = 4." | 2.73 | Preventive effects of treatment of disruptive behavior disorder in middle childhood on substance use and delinquent behavior. ( Lochman, JE; Matthys, W; van de Wiel, NMH; Zonnevylle-Bender, MJS, 2007) |
| "Methylphenidate is an effective short-term treatment for oppositional behavior in children with comorbid ADHD and chronic multiple tic disorder." | 2.73 | Methylphenidate in children with oppositional defiant disorder and both comorbid chronic multiple tic disorder and ADHD. ( Gadow, KD; Nolan, EE; Schneider, J; Sprafkin, J; Sverd, J, 2008) |
| "The current study was aimed at (a) investigating the effect of three doses methylphenidate (MPH) and placebo on inhibition of a prepotent response, inhibition of an ongoing response, and interference control in Attention Deficit/Hyperactivity Disorder (AD/HD), and (b) studying dose-response relations for the three forms of response inhibition." | 2.71 | The effect of methylphenidate on three forms of response inhibition in boys with AD/HD. ( Meiran, N; Morein-Zamir, S; Oosterlaan, J; Scheres, A; Schut, H; Sergeant, JA; Swanson, J; Vlasveld, L, 2003) |
| "We used a sequential approach to evaluate the relative and combined effects of different types of behavioral treatments, as well as dosage of methylphenidate (MPH), on the disruptive behavior of 3 students who had been diagnosed with attention deficit hyperactivity disorder." | 2.71 | Sequential evaluation of behavioral treatments and methylphenidate dosage for children with attention deficit hyperactivity disorder. ( Gulley, V; Hupp, S; LeVelle, J; Northup, J; Ridgway, A; Spera, S, 2003) |
| "Methylphenidate seems to be an effective treatment for ODD, as well as for ADHD itself." | 2.71 | The effect of methylphenidate on oppositional defiant disorder comorbid with attention deficit/hyperactivity disorder. ( Gomes, F; Mattos, P; Pastura, G; Serra-Pinheiro, MA; Souza, I, 2004) |
| "Risperidone-treated patients had clinically and statistically significant reductions in both disruptive behavior and hyperactivity subscale scores, compared to placebo, regardless of concomitant stimulant use." | 2.71 | Risperidone effects in the presence/absence of psychostimulant medicine in children with ADHD, other disruptive behavior disorders, and subaverage IQ. ( Aman, MG; Binder, C; Turgay, A, 2004) |
| "To assess how threshold oppositional defiant disorder (ODD), inattention, and hyperactivity-impulsivity affect the response to atomoxetine versus methylphenidate." | 2.48 | How oppositionality, inattention, and hyperactivity affect response to atomoxetine versus methylphenidate: a pooled meta-analysis. ( Granger, RE; Hazell, PL; Kohn, MR; van Wyk, GW; Walton, RJ, 2012) |
| "Although the relationship between attention-deficit/hyperactivity disorder (ADHD) and transport accidents has been shown, there is limited information on the relationship between medication and dose-response effects and transport accident risk." | 1.62 | Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH. ( Chen, VC; Chen, YL; Gossop, M; Liu, YC; Yang, YH, 2021) |
| "Conduct disorder (CD) and oppositional defiant disorder (ODD), collectively termed disruptive behavior disorders (DBDs), are a major cause of impairment and suffering in those affected by these conditions and their families and communities." | 1.48 | Does Methylphenidate Normalize Brain Dysfunction During Fear Learning in Adolescents With Disruptive Behavior Disorders? ( Fairchild, G, 2018) |
| "Methylphenidate treatment did not significantly change any parameter of sleep architecture." | 1.43 | Sleep in children with attention-deficit/hyperactivity disorder (ADHD) before and after 6-month treatment with methylphenidate: a pilot study. ( Bagnasco, I; Cortese, S; Delia, G; Galloni, GB; Mana, M; Moletto, A; Vigliano, P, 2016) |
| "Baseline oppositional defiant disorder (ODD) and conduct disorder (CD) scores were correlated with the CGI-S score; however, no association was found between core ADHD symptom severity and the CGI-S score." | 1.40 | Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder. ( Bilgiç, A; Hergüner, S; Yılmaz, S, 2014) |
| "Methylphenidate (MPH) is a phenethylamine derivative used in the treatment of childhood attention-deficit hyperactivity disorder." | 1.35 | Development and validation of a liquid chromatography-mass spectrometry assay for hair analysis of methylphenidate. ( García-Algar, O; Marchei, E; Muñoz, JA; Pellegrini, M; Pichini, S; Vall, O; Zuccaro, P, 2008) |
| "Children with ADHD and Oppositional Defiant Disorder (ODD) prescribed stimulants reported feeling better behaved." | 1.30 | Do stimulants improve self-esteem in children with ADHD and peer problems? ( Cantwell, DP; Feinberg, DT; Frankel, F; Myatt, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (2.41) | 18.2507 |
| 2000's | 36 (43.37) | 29.6817 |
| 2010's | 42 (50.60) | 24.3611 |
| 2020's | 3 (3.61) | 2.80 |
| Authors | Studies |
|---|---|
| Briegel, W | 1 |
| Liu, YC | 1 |
| Chen, VC | 1 |
| Yang, YH | 1 |
| Chen, YL | 1 |
| Gossop, M | 1 |
| Golubchik, P | 4 |
| Weizman, A | 4 |
| da Silva, BS | 1 |
| Cupertino, RB | 1 |
| Rovaris, DL | 1 |
| Schuch, JB | 1 |
| Kappel, DB | 1 |
| Müller, D | 1 |
| Bandeira, CE | 1 |
| Victor, MM | 1 |
| Karam, RG | 1 |
| Mota, NR | 1 |
| Rohde, LA | 3 |
| Contini, V | 1 |
| Grevet, EH | 1 |
| Bau, CHD | 1 |
| Masi, G | 2 |
| Manfredi, A | 2 |
| Nieri, G | 1 |
| Muratori, P | 2 |
| Pfanner, C | 1 |
| Milone, A | 2 |
| van der Veen-Mulders, L | 1 |
| van den Hoofdakker, BJ | 1 |
| Nauta, MH | 1 |
| Emmelkamp, P | 1 |
| Hoekstra, PJ | 1 |
| Winters, DE | 1 |
| Fukui, S | 1 |
| Leibenluft, E | 2 |
| Hulvershorn, LA | 1 |
| Levy, T | 1 |
| Pan, PY | 1 |
| Fu, AT | 1 |
| Yeh, CB | 1 |
| Fairchild, G | 1 |
| van Lith, K | 1 |
| Veltman, DJ | 1 |
| Cohn, MD | 1 |
| Pape, LE | 1 |
| van den Akker-Nijdam, ME | 1 |
| van Loon, AWG | 1 |
| Bet, P | 1 |
| van Wingen, GA | 1 |
| van den Brink, W | 1 |
| Doreleijers, T | 1 |
| Popma, A | 1 |
| Shalev, L | 1 |
| Tsamir, D | 1 |
| Manor, I | 1 |
| Towbin, K | 1 |
| Vidal-Ribas, P | 1 |
| Brotman, MA | 1 |
| Pickles, A | 1 |
| Miller, KV | 1 |
| Kaiser, A | 1 |
| Vitale, AD | 1 |
| Engel, C | 1 |
| Overman, GP | 1 |
| Davis, M | 1 |
| Lee, B | 1 |
| McNeil, C | 1 |
| Wheeler, W | 1 |
| Yokum, CH | 1 |
| Haring, CT | 1 |
| Roule, A | 1 |
| Wambach, CG | 1 |
| Sharif-Askary, B | 1 |
| Pine, DS | 1 |
| Stringaris, A | 1 |
| Salisbury-Afshar, E | 1 |
| Yılmaz, S | 1 |
| Bilgiç, A | 1 |
| Hergüner, S | 2 |
| Newcorn, JH | 2 |
| Blader, JC | 2 |
| Pliszka, SR | 2 |
| Kafantaris, V | 2 |
| Foley, CA | 1 |
| Crowell, JA | 1 |
| Carlson, GA | 1 |
| Sauder, CL | 1 |
| Margulies, DM | 1 |
| Sinha, C | 1 |
| Sverd, J | 2 |
| Matthews, TL | 1 |
| Bailey, BY | 1 |
| Daviss, WB | 1 |
| Lidzba, K | 1 |
| Granstroem, S | 1 |
| Leark, RA | 1 |
| Kraegeloh-Mann, I | 1 |
| Mautner, VF | 1 |
| Elbe, D | 1 |
| Barr, AM | 1 |
| Honer, WG | 1 |
| Procyshyn, RM | 1 |
| Rubia, K | 1 |
| Alegría, AA | 1 |
| Brinson, H | 1 |
| Özayhan, HY | 1 |
| Vigliano, P | 1 |
| Galloni, GB | 1 |
| Bagnasco, I | 1 |
| Delia, G | 1 |
| Moletto, A | 1 |
| Mana, M | 1 |
| Cortese, S | 1 |
| Brovedani, P | 1 |
| Pisano, S | 1 |
| Tzang, RF | 1 |
| Chang, YC | 1 |
| Tsai, GE | 1 |
| Lane, HY | 1 |
| Ding, K | 1 |
| Yang, J | 1 |
| Reynolds, GP | 1 |
| Chen, B | 1 |
| Shao, J | 1 |
| Liu, R | 1 |
| Qian, Q | 1 |
| Liu, H | 1 |
| Yang, R | 1 |
| Wen, J | 1 |
| Kang, C | 1 |
| Dose, C | 1 |
| Hautmann, C | 1 |
| Buerger, M | 1 |
| Schuermann, S | 1 |
| Woitecki, K | 1 |
| Doepfner, M | 1 |
| Jahangard, L | 1 |
| Akbarian, S | 1 |
| Haghighi, M | 1 |
| Ahmadpanah, M | 1 |
| Keshavarzi, A | 1 |
| Bajoghli, H | 1 |
| Sadeghi Bahmani, D | 1 |
| Holsboer-Trachsler, E | 1 |
| Brand, S | 1 |
| Findling, RL | 1 |
| Karama, S | 1 |
| Ben Amor, L | 1 |
| Grizenko, N | 3 |
| Ciampi, A | 1 |
| Mbekou, V | 1 |
| Ter-Stepanian, M | 2 |
| Lageix, P | 1 |
| Baron, C | 1 |
| Schwartz, G | 2 |
| Joober, R | 3 |
| Symons, RC | 1 |
| Mainster, MA | 1 |
| Goldberg, MF | 1 |
| Keen, D | 2 |
| Hadijikoumi, I | 2 |
| Schooler, NR | 1 |
| Jensen, PS | 2 |
| Rothermel, B | 1 |
| Poustka, L | 1 |
| Banaschewski, T | 1 |
| Becker, K | 1 |
| Marchant, BK | 4 |
| Reimherr, FW | 4 |
| Robison, RJ | 2 |
| Olsen, JL | 2 |
| Kondo, DG | 1 |
| Zappitelli, M | 1 |
| Halls, C | 1 |
| Williams, ED | 2 |
| Strong, RE | 2 |
| Tagaya, H | 1 |
| Volpe, RJ | 1 |
| Briesch, AM | 1 |
| Gadow, KD | 2 |
| van Wyk, GW | 1 |
| Hazell, PL | 2 |
| Kohn, MR | 1 |
| Granger, RE | 1 |
| Walton, RJ | 1 |
| Philipsen, A | 1 |
| Graf, E | 1 |
| Tebartz van Elst, L | 1 |
| Jans, T | 1 |
| Warnke, A | 1 |
| Hesslinger, B | 1 |
| Ebert, D | 1 |
| Gerlach, M | 1 |
| Matthies, S | 1 |
| Colla, M | 1 |
| Jacob, C | 1 |
| Sobanski, E | 1 |
| Alm, B | 1 |
| Rösler, M | 1 |
| Ihorst, G | 1 |
| Gross-Lesch, S | 1 |
| Gentschow, L | 1 |
| Kis, B | 1 |
| Huss, M | 1 |
| Lieb, K | 1 |
| Schlander, M | 1 |
| Berger, M | 1 |
| Chazan, R | 1 |
| Borowski, C | 1 |
| Pianca, T | 1 |
| Ludwig, H | 1 |
| Polanczyk, G | 1 |
| Marcus, SC | 1 |
| Durkin, M | 1 |
| Vashi, NA | 1 |
| Souza, A | 1 |
| Cohen, N | 1 |
| Franklin, B | 1 |
| Cohen, DE | 1 |
| Wender, PH | 1 |
| Goetz, M | 1 |
| Prihodova, I | 1 |
| Hrdlicka, M | 1 |
| De Benedictis, L | 1 |
| Dumais, A | 1 |
| Landry, P | 1 |
| Cheng, JT | 1 |
| Li, JS | 1 |
| Scheres, A | 1 |
| Oosterlaan, J | 2 |
| Swanson, J | 1 |
| Morein-Zamir, S | 1 |
| Meiran, N | 1 |
| Schut, H | 1 |
| Vlasveld, L | 1 |
| Sergeant, JA | 1 |
| Stuart, JE | 1 |
| Arnold, LE | 1 |
| Elliot, M | 1 |
| Sachs, L | 1 |
| Bird, H | 1 |
| Kraemer, HC | 1 |
| Wells, KC | 1 |
| Abikoff, HB | 3 |
| Comarda, A | 1 |
| Conners, CK | 1 |
| Elliott, GR | 2 |
| Greenhill, LL | 3 |
| Hechtman, L | 1 |
| Hindshaw, SP | 1 |
| Hoza, B | 1 |
| March, JS | 1 |
| Pelham, WE | 2 |
| Severe, JB | 1 |
| Swanson, JM | 3 |
| Vitiello, B | 3 |
| Wigal, T | 3 |
| Gulley, V | 2 |
| Northup, J | 2 |
| Hupp, S | 1 |
| Spera, S | 1 |
| LeVelle, J | 1 |
| Ridgway, A | 1 |
| Erasmus, J | 1 |
| Serra-Pinheiro, MA | 1 |
| Mattos, P | 1 |
| Souza, I | 1 |
| Pastura, G | 1 |
| Gomes, F | 1 |
| Aman, MG | 1 |
| Binder, C | 1 |
| Turgay, A | 1 |
| Gross-Tsur, V | 1 |
| Joseph, A | 1 |
| Shalev, RS | 1 |
| Schweitzer, JB | 1 |
| Lee, DO | 1 |
| Hanford, RB | 1 |
| Zink, CF | 1 |
| Ely, TD | 1 |
| Tagamets, MA | 1 |
| Hoffman, JM | 1 |
| Grafton, ST | 1 |
| Kilts, CD | 1 |
| Cheon, KA | 1 |
| Ryu, YH | 1 |
| Kim, JW | 1 |
| Cho, DY | 1 |
| Hewitt, KN | 1 |
| Shah, YB | 1 |
| Prior, MJ | 1 |
| Morris, PG | 1 |
| Hollis, CP | 1 |
| Fone, KC | 1 |
| Marsden, CA | 1 |
| Dicesare, A | 1 |
| McAdam, DB | 1 |
| Toner, A | 1 |
| Varrell, J | 1 |
| Vaidya, CJ | 1 |
| Bunge, SA | 1 |
| Dudukovic, NM | 1 |
| Zalecki, CA | 1 |
| Gabrieli, JD | 1 |
| Zonnevylle-Bender, MJS | 1 |
| Matthys, W | 2 |
| van de Wiel, NMH | 1 |
| Lochman, JE | 2 |
| Waschbusch, DA | 1 |
| Craig, R | 1 |
| King, S | 1 |
| Prabhuswamy, M | 1 |
| Srinath, S | 1 |
| Girimaji, S | 1 |
| Seshadri, S | 1 |
| Mestas, R | 1 |
| Soni, P | 1 |
| Sabuncuoglu, O | 1 |
| van de Wiel, NM | 1 |
| Cohen-Kettenis, PT | 1 |
| Maassen, GH | 1 |
| van Engeland, H | 1 |
| Pae, CU | 1 |
| Symons, FJ | 1 |
| Tervo, RC | 1 |
| Kim, O | 1 |
| Hoch, J | 1 |
| Goez, H | 1 |
| Back-Bennet, O | 1 |
| Zelnik, N | 1 |
| Gruber, R | 1 |
| Bellingham, J | 1 |
| Guzman, R | 1 |
| Maia, CR | 1 |
| Matte, BC | 1 |
| Ludwig, HT | 1 |
| Posner, K | 2 |
| Melvin, GA | 1 |
| Murray, DW | 2 |
| Gugga, SS | 1 |
| Fisher, P | 1 |
| Skrobala, A | 1 |
| Cunningham, C | 2 |
| Ghuman, JK | 2 |
| Kollins, S | 1 |
| Wigal, SB | 2 |
| McCracken, JT | 2 |
| McGough, JJ | 2 |
| Kastelic, E | 2 |
| Boorady, R | 1 |
| Davies, M | 2 |
| Chuang, SZ | 2 |
| Riddle, MA | 2 |
| Kollins, SH | 1 |
| Scharko, AM | 1 |
| Evans, L | 1 |
| Skrobala, AM | 1 |
| Marchei, E | 1 |
| Muñoz, JA | 1 |
| García-Algar, O | 1 |
| Pellegrini, M | 1 |
| Vall, O | 1 |
| Zuccaro, P | 1 |
| Pichini, S | 1 |
| Van der Oord, S | 1 |
| Prins, PJ | 1 |
| Emmelkamp, PM | 1 |
| DelBello, MP | 1 |
| Nolan, EE | 1 |
| Sprafkin, J | 1 |
| Schneider, J | 1 |
| Chabot, RJ | 1 |
| Orgill, AA | 1 |
| Crawford, G | 1 |
| Harris, MJ | 1 |
| Serfontein, G | 1 |
| Frankel, F | 1 |
| Cantwell, DP | 1 |
| Myatt, R | 1 |
| Feinberg, DT | 1 |
| Reitman, D | 1 |
| Hupp, SD | 1 |
| O'Callaghan, PM | 1 |
| Kariyawasam, SH | 1 |
| Zaw, F | 1 |
| Handley, SL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Controlled Trial of Citalopram Added to Methylphenidate in Youth With Severe Mood Dysregulation[NCT00794040] | Phase 2 | 103 participants (Actual) | Interventional | 2008-11-17 | Completed | ||
| Double-Blind, Placebo-Controlled Trial of Flexible Dose Divalproex Sodium Adjunctive to Stimulant Treatment for Aggressive Children With Attention-Deficit Hyperactivity Disorder[NCT00228046] | Phase 4 | 40 participants (Anticipated) | Interventional | 2004-01-31 | Completed | ||
| Adjunctive Treatment With Divalproex or Risperidone for Aggression Refractory to Stimulant Monotherapy Among Children With ADHD[NCT00794625] | Phase 4 | 270 participants (Anticipated) | Interventional | 2008-11-30 | Recruiting | ||
| Enhancement of Psychosocial Functioning, Quality of Life, Satisfaction With Medication and Medication Compliance of Methylphenidate Treatment by Psychosocial Intervention and Support[NCT01660425] | 100 participants (Anticipated) | Interventional | 2012-05-31 | Active, not recruiting | |||
| Virtual Reality Attention Management Program for Improving Attention in Children[NCT03221244] | 50 participants (Anticipated) | Interventional | 2016-06-02 | Recruiting | |||
| Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)[NCT00483106] | Phase 4 | 885 participants (Actual) | Interventional | 1999-11-30 | Completed | ||
| Concerta in the Treatment of Adult ADHD and a Comparison of Four Adult ADHD Scales and Effects on Personality[NCT02215538] | Phase 2/Phase 3 | 47 participants (Actual) | Interventional | 2004-11-30 | Completed | ||
| Methylphenidate Transdermal System (MTS) in the Treatment of Adult ADHD[NCT00506285] | Phase 3 | 92 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Multimodal Treatment Study of Children With ADHD[NCT00000388] | Phase 4 | 0 participants | Interventional | 1998-09-30 | Completed | ||
| Neuroplasticity Technology for Attention-deficit/Hyperactivity Disorder (ADHD)[NCT03363568] | 41 participants (Actual) | Interventional | 2013-07-18 | Completed | |||
| The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD)[NCT04964427] | 26 participants (Actual) | Interventional | 2021-02-08 | Completed | |||
| Pediatric Attention Deficit Hyperactivity Disorder: Predicting Clinical Response to Stimulant Medication From Single-dose Changes in Event Related Potentials[NCT02695355] | Phase 2 | 87 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"A measure of change of irritability severity taking the baseline before randomization as a reference. Scores range 1 to 8, in which 1=Completely recovered,... 5=Unchanged,... 8=Much worse.~Percentage of participants who responded are based on an estimation and might not match exactly with discrete numbers of participants based on the denominator." (NCT00794040)
Timeframe: Collected weekly during the 8-week trial. The 8th-week outcome is reported.
| Intervention | estimated percentage of participants (Number) |
|---|---|
| Add-on Citalopram Following Optimized Methylphenidate | 35 |
| Add-on Placebo Following Optimized Methylphenidate | 6 |
Difference in anxiety symptoms at 8th week of trial as measured with the Pediatric Anxiety Rating Scale (PARS) with scores ranging 0-25. Higher values represent a worse outcome. (NCT00794040)
Timeframe: Collected weekly during the 8th week trial. The 8th-week outcome is reported.
| Intervention | units on a scale (Mean) |
|---|---|
| Add-on Citalopram Following Optimized Methylphenidate | 12.0 |
| Add-on Placebo Following Optimized Methylphenidate | 13.4 |
Difference in depressive symptoms at 8th week of trial as measured with Children's Depression Rating Scale (CDRS) with scores ranging 17-113, where scores >40 are considered over the clinical threshold, and scores <28 are considered within the healthy range. (NCT00794040)
Timeframe: Collected weekly during the 8th week trial. The 8th-week outcome is reported.
| Intervention | units on a scale (Mean) |
|---|---|
| Add-on Citalopram Following Optimized Methylphenidate | 28.6 |
| Add-on Placebo Following Optimized Methylphenidate | 30.1 |
Difference in functional impairment at 8th week of trial as measured with Children's Global Impression Scale (CGAS) with scores ranging from 1=Most impaired to 100=Not impaired at all. (NCT00794040)
Timeframe: Collected weekly during the 8th week trial. The 8th-week outcome is reported.
| Intervention | units on a scale (Mean) |
|---|---|
| Add-on Citalopram Following Optimized Methylphenidate | 52.6 |
| Add-on Placebo Following Optimized Methylphenidate | 47.2 |
Clinical Global Impression-Severity (CGI-S): A measure of severity of irritability scale (from 1=Normal, not at all ill to 7=Among the most extremely ill patients). (NCT00794040)
Timeframe: Collected weekly during the 8th week trial. The 8th-week outcome is reported.
| Intervention | units on a scale (Mean) |
|---|---|
| Add-on Citalopram Following Optimized Methylphenidate | 3.1 |
| Add-on Placebo Following Optimized Methylphenidate | 3.9 |
Measures the DSM based ADHD criteria of Inattention and Hyperactivity/Impulsivity. There are 30 items scored 0-3 for a minimum score of 0 (no symptoms) and a maximum score of 90 worst possible symptoms. (NCT00506285)
Timeframe: Double-blind endpoints for MTS and placebo arms
| Intervention | units on a scale (Mean) |
|---|---|
| Scores in MTS Arm | 30.8 |
| Scores in Placebo Arm | 49.5 |
This scale measures the 7 domains of the Utah Criteria for Adult ADHD. Total scores run from 0 to 28. Normative samples average below 5. The worst possible score is 28. (NCT00506285)
Timeframe: Double-blind endpoints during MTS and placebo arms
| Intervention | units on a scale (Mean) |
|---|---|
| Scores in MTS Arm | 11.0 |
| Scores in Placebo Arm | 17.9 |
8 reviews available for methylphenidate and Attention Deficit and Disruptive Behavioral Disorders
| Article | Year |
|---|---|
ADHD interventions in children younger than six years.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2013 |
Brain abnormalities in attention-deficit hyperactivity disorder: a review.
Topics: Adolescent; Adult; Atomoxetine Hydrochloride; Attention Deficit and Disruptive Behavior Disorders; A | 2014 |
Atypical antipsychotic treatment of disruptive behavior disorders in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders; | 2008 |
ADHD in children and adolescents.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit and Disruptive Behavior Disorders; Attentio | 2008 |
[Methylphenidate: pharmacology, indication and potential of abuse].
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Humans; Male; Methylphenidate; Narcoleps | 2010 |
How oppositionality, inattention, and hyperactivity affect response to atomoxetine versus methylphenidate: a pooled meta-analysis.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit and Disruptive Behavior Disorders; Attentio | 2012 |
ADHD in children and adolescents.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit and Disruptive Behavior Disorders; Attentio | 2011 |
Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2008 |
39 trials available for methylphenidate and Attention Deficit and Disruptive Behavioral Disorders
| Article | Year |
|---|---|
A Naturalistic Comparison of Methylphenidate and Risperidone Monotherapy in Drug-Naive Youth With Attention-Deficit/Hyperactivity Disorder Comorbid With Oppositional Defiant Disorder and Aggression.
Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Def | 2017 |
Methylphenidate Has Superior Efficacy Over Parent-Child Interaction Therapy for Preschool Children with Disruptive Behaviors.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperact | 2018 |
The effect of methylphenidate treatment on psychopathic behavior of patients having attention-deficit hyperactivity disorder with and without oppositional defiant disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2018 |
Aripiprazole/Methylphenidate Combination in Children and Adolescents with Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder: An Open-Label Study.
Topics: Adolescent; Antidepressive Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders | 2018 |
Effects of Methylphenidate During Fear Learning in Antisocial Adolescents: A Randomized Controlled fMRI Trial.
Topics: Adolescent; Amygdala; Attention Deficit and Disruptive Behavior Disorders; Brain Mapping; Central Ne | 2018 |
A Double-Blind Randomized Placebo-Controlled Trial of Citalopram Adjunctive to Stimulant Medication in Youth With Chronic Severe Irritability.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 2020 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Sarcosine treatment for oppositional defiant disorder symptoms of attention deficit hyperactivity disorder children.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2016 |
Telephone-assisted self-help for parents of children with attention-deficit/hyperactivity disorder who have residual functional impairment despite methylphenidate treatment: a randomized controlled trial.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperact | 2017 |
Children with ADHD and symptoms of oppositional defiant disorder improved in behavior when treated with methylphenidate and adjuvant risperidone, though weight gain was also observed - Results from a randomized, double-blind, placebo-controlled clinical t
Topics: Adjuvants, Pharmaceutic; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Diso | 2017 |
Factor structure of the restricted academic situation scale: implications for ADHD.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2009 |
Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy.
Topics: Adolescent; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorders; Atten | 2009 |
Methylphenidate transdermal system in adult ADHD and impact on emotional and oppositional symptoms.
Topics: Administration, Cutaneous; Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Def | 2011 |
Clinical response to methylphenidate in children diagnosed with attention-deficit hyperactivity disorder and comorbid psychiatric disorders.
Topics: Anxiety Disorders; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder w | 2010 |
OROS methylphenidate in the treatment of adults with ADHD: a 6-month, open-label, follow-up study.
Topics: Affective Symptoms; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder | 2010 |
Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial.
Topics: Adolescent; Adult; Attention Deficit and Disruptive Behavior Disorders; Behavior Therapy; Central Ne | 2010 |
Oppositional defiant disorder in adults with ADHD.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperact | 2013 |
The effect of methylphenidate on three forms of response inhibition in boys with AD/HD.
Topics: Attention; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hype | 2003 |
A randomized controlled trial of clonidine added to psychostimulant medication for hyperactive and aggressive children.
Topics: Adolescent; Aggression; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disor | 2003 |
Effects of ethnicity on treatment attendance, stimulant response/dose, and 14-month outcome in ADHD.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2003 |
Sequential evaluation of behavioral treatments and methylphenidate dosage for children with attention deficit hyperactivity disorder.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2003 |
The effect of methylphenidate on oppositional defiant disorder comorbid with attention deficit/hyperactivity disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2004 |
Risperidone effects in the presence/absence of psychostimulant medicine in children with ADHD, other disruptive behavior disorders, and subaverage IQ.
Topics: Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorde | 2004 |
Effect of methylphenidate on executive functioning in adults with attention-deficit/hyperactivity disorder: normalization of behavior but not related brain activity.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Behavioral Symptoms; Brain; Brain Mappin | 2004 |
The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate.
Topics: Alleles; Attention Deficit and Disruptive Behavior Disorders; Brain; Brain Mapping; Central Nervous | 2005 |
The effects of methylphenidate on a functional analysis of disruptive behavior: a replication and extension.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Behavior; Behavior Therapy; Central | 2005 |
Preventive effects of treatment of disruptive behavior disorder in middle childhood on substance use and delinquent behavior.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 2007 |
Self-handicapping prior to academic-oriented tasks in children with attention deficit/hyperactivity disorder (ADHD): medication effects and comparisons with controls.
Topics: Adolescent; Aptitude; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorde | 2007 |
A double-blind, placebo-controlled, crossover study of osmotic release oral system methylphenidate in adults with ADHD with assessment of oppositional and emotional dimensions of the disorder.
Topics: Administration, Oral; Adult; Affective Symptoms; Attention Deficit and Disruptive Behavior Disorders | 2007 |
The effectiveness of an experimental treatment when compared to care as usual depends on the type of care as usual.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2007 |
The effects of methylphenidate on the classroom behavior of elementary school-age children with cerebral palsy: a preliminary observational analysis.
Topics: Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; Cerebral Pal | 2007 |
Differential stimulant response on attention in children with comorbid anxiety and oppositional defiant disorder.
Topics: Adolescent; Anxiety; Attention; Attention Deficit and Disruptive Behavior Disorders; Central Nervous | 2007 |
Performance on the continuous performance test in children with ADHD is associated with sleep efficiency.
Topics: Arousal; Attention; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder | 2007 |
Switching from methylphenidate immediate release to MPH-SODAS in attention-deficit/hyperactivity disorder.
Topics: Administration, Oral; Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit | 2008 |
Clinical presentation of attention-deficit/hyperactivity disorder in preschool children: the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS).
Topics: Anxiety Disorders; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder w | 2007 |
Comorbidity moderates response to methylphenidate in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS).
Topics: Age Factors; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hy | 2007 |
Methylphenidate in children with oppositional defiant disorder and both comorbid chronic multiple tic disorder and ADHD.
Topics: Age Factors; Aggression; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Diso | 2008 |
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 1999 |
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 1999 |
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 1999 |
Behavioral and electrophysiologic predictors of treatment response to stimulants in children with attention disorders.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 1999 |
The influence of a token economy and methylphenidate on attentive and disruptive behavior during sports with ADHD-diagnosed children.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2001 |
36 other studies available for methylphenidate and Attention Deficit and Disruptive Behavioral Disorders
| Article | Year |
|---|---|
Psychiatric Comorbidities in 1p36 Deletion Syndrome and Their Treatment-A Case Report.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2021 |
Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH.
Topics: Accidents, Traffic; Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Defic | 2021 |
The Possible Effect of Methylphenidate Treatment on Empathy in Children Diagnosed with Attention-Deficit/Hyperactivity Disorder, Both With and Without Comorbid Oppositional Defiant Disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2017 |
Exocytosis-related genes and response to methylphenidate treatment in adults with ADHD.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperact | 2018 |
The effect of methylphenidate treatment on suspiciousness in children with ADHD alone or comorbid with ODD.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2018 |
Improvements in Irritability with Open-Label Methylphenidate Treatment in Youth with Comorbid Attention Deficit/Hyperactivity Disorder and Disruptive Mood Dysregulation Disorder.
Topics: Adolescent; Affective Symptoms; Attention Deficit and Disruptive Behavior Disorders; Attention Defic | 2018 |
Does Methylphenidate Normalize Brain Dysfunction During Fear Learning in Adolescents With Disruptive Behavior Disorders?
Topics: Adolescent; Adult; Attention Deficit and Disruptive Behavior Disorders; Brain; Child; Conduct Disord | 2018 |
High pretreatment cognitive impulsivity predicts response of oppositional symptoms to methylphenidate in patients with attention-deficit hyperactivity disorder/oppositional defiant disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2019 |
Effect of OROS methylphenidate on encopresis in children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2014 |
Can children with callous and unemotional traits be treated successfully?
Topics: Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior Disorders; Ce | 2013 |
Pharmacotherapy of attention deficit in neurofibromatosis type 1: effects on cognition.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Child; Cognition; Dopamine Uptake I | 2014 |
Managing ADHD and disruptive behaviour disorders with combination psychostimulant and antipsychotic treatment.
Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Def | 2014 |
Visual Hallucinations with Methylphenidate and Acetaminophen in Combination.
Topics: Acetaminophen; Antipyretics; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit | 2015 |
Sleep in children with attention-deficit/hyperactivity disorder (ADHD) before and after 6-month treatment with methylphenidate: a pilot study.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; | 2016 |
Combined pharmacotherapy-multimodal psychotherapy in children with Disruptive Behavior Disorders.
Topics: Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Def | 2016 |
DAT1 methylation is associated with methylphenidate response on oppositional and hyperactive-impulsive symptoms in children and adolescents with ADHD.
Topics: Attention Deficit and Disruptive Behavior Disorders; Child; DNA Methylation; Dopamine Plasma Membran | 2017 |
Solar maculopathy in a young child.
Topics: Attention Deficit and Disruptive Behavior Disorders; Child; Dopamine Uptake Inhibitors; Humans; Macu | 2010 |
[Bipolar disorders as co-morbidity in childhood and adolescence--underdiagnosed or overinterpreted? Therapy of a 14-year-old boy with hyperkinetic conduct disorder and hypomania].
Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; A | 2010 |
The efficiency of behavior rating scales to assess inattentive-overactive and oppositional-defiant behaviors: applying generalizability theory to streamline assessment.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2011 |
Do phenotypic characteristics, parental psychopathology, family functioning, and environmental stressors have a role in the response to methylphenidate in children with attention-deficit/hyperactivity disorder? A naturalistic study from a developing count
Topics: Adolescent; Adult; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder w | 2011 |
Stimulant adherence and academic performance in urban youth with attention-deficit/hyperactivity disorder.
Topics: Achievement; Adolescent; Amphetamine; Anxiety Disorders; Attention Deficit and Disruptive Behavior D | 2011 |
Allergic contact dermatitis caused by methylphenidate.
Topics: Anti-Inflammatory Agents; Attention Deficit and Disruptive Behavior Disorders; Central Nervous Syste | 2011 |
Long lasting complex nocturnal hallucinations during Osmotic Release Oral System (OROS) methylphenidate treatment in a 7-year old girl.
Topics: Administration, Oral; Attention Deficit and Disruptive Behavior Disorders; Central Nervous System St | 2011 |
Successful treatment of severe disruptive disorder featuring symptoms of the Klüver-Bucy Syndrome following a massive right temporal-parietal hemorrhage.
Topics: Adrenergic alpha-Agonists; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Di | 2013 |
Intra-orbitofrontal cortex injection of haloperidol removes the beneficial effect of methylphenidate on reversal learning of spontaneously hypertensive rats in an attentional set-shifting task.
Topics: Animals; Attention; Attention Deficit and Disruptive Behavior Disorders; Disease Models, Animal; Dop | 2013 |
Ritalin--on the bandwagon?
Topics: Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; Child; Child | 2003 |
Hallucinations during methylphenidate therapy.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2004 |
Behavioural and pharmacological magnetic resonance imaging assessment of the effects of methylphenidate in a potential new rat model of attention deficit hyperactivity disorder.
Topics: Analysis of Variance; Animals; Animals, Newborn; Attention Deficit and Disruptive Behavior Disorders | 2005 |
Altered neural substrates of cognitive control in childhood ADHD: evidence from functional magnetic resonance imaging.
Topics: Attention Deficit and Disruptive Behavior Disorders; Brain Mapping; Central Nervous System Stimulant | 2005 |
Methylphenidate and hypertension.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2006 |
Risperidone-to-methylphenidate switch reaction in children: three cases.
Topics: Adolescent; Akathisia, Drug-Induced; Antipsychotic Agents; Attention Deficit and Disruptive Behavior | 2007 |
Comments on efficacy and tolerability of OROS methylphenidate in Korean children with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2007 |
Development and validation of a liquid chromatography-mass spectrometry assay for hair analysis of methylphenidate.
Topics: Attention Deficit and Disruptive Behavior Disorders; Central Nervous System Stimulants; Child; Foren | 2008 |
Attention-deficit/hyperactivity disorder: advances in diagnostic and therapeutic approaches.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyp | 2008 |
Do stimulants improve self-esteem in children with ADHD and peer problems?
Topics: Analysis of Variance; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorde | 1999 |
Reduced salivary cortisol in children with comorbid Attention deficit hyperactivity disorder and oppositional defiant disorder.
Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; | 2002 |