methylphenidate has been researched along with Apnea, Sleep in 8 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with sleep apnea, brainstem functional activity is low in the awake state but becomes critically reduced during sleep, culminating in apnea-stimulated arousal followed by repetitive cycles as sleep recurs." | 1.26 | Sleep apnea, narcolepsy, and dreaming: regional cerebral hemodynamics. ( Derman, S; Karacan, I; Meyer, JS; Sakai, F; Yamamoto, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Padala, PR | 1 |
| Dennis, RA | 1 |
| Padala, KP | 1 |
| Kolla, BP | 1 |
| Mansukhani, MP | 1 |
| Golan, N | 2 |
| Shahar, E | 1 |
| Ravid, S | 1 |
| Pillar, G | 2 |
| Huang, YS | 1 |
| Guilleminault, C | 1 |
| Li, HY | 1 |
| Yang, CM | 1 |
| Wu, YY | 1 |
| Chen, NH | 1 |
| Corkum, P | 1 |
| Panton, R | 1 |
| Ironside, S | 1 |
| Macpherson, M | 1 |
| Williams, T | 1 |
| Meyer, JS | 1 |
| Sakai, F | 1 |
| Karacan, I | 1 |
| Derman, S | 1 |
| Yamamoto, M | 1 |
| van der Meché, FG | 1 |
| Bogaard, JM | 1 |
| van der Sluys, JC | 1 |
| Schimsheimer, RJ | 1 |
| Ververs, CC | 1 |
| Busch, HF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Validation of Sleep Questionnaires in the Down Syndrome Population[NCT03771469] | 81 participants (Actual) | Interventional | 2018-06-25 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methylphenidate and Apnea, Sleep
| Article | Year |
|---|---|
[The relationship between attention deficit hyperactivity disorder and sleep-alertness problems].
Topics: Adrenergic Uptake Inhibitors; Attention Deficit Disorder with Hyperactivity; Child; Dopamine Agents; | 2004 |
1 trial available for methylphenidate and Apnea, Sleep
| Article | Year |
|---|---|
Acute impact of immediate release methylphenidate administered three times a day on sleep in children with attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Biological Availability; Brain; Central Nervous Syste | 2008 |
6 other studies available for methylphenidate and Apnea, Sleep
| Article | Year |
|---|---|
Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani.
Topics: Alzheimer Disease; Apathy; Double-Blind Method; Humans; Independent Living; Methylphenidate; Sleep A | 2018 |
Methylphenidate and Apathy in Alzheimer's Disease: Is Sleep Apnea a Confounding Effect?
Topics: Alzheimer Disease; Apathy; Double-Blind Method; Humans; Independent Living; Methylphenidate; Sleep A | 2018 |
Sleep disorders and daytime sleepiness in children with attention-deficit/hyperactive disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Disorders o | 2004 |
Attention-deficit/hyperactivity disorder with obstructive sleep apnea: a treatment outcome study.
Topics: Adenoidectomy; Adenoids; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimu | 2007 |
Sleep apnea, narcolepsy, and dreaming: regional cerebral hemodynamics.
Topics: Adult; Brain Stem; Cerebellum; Cerebrovascular Circulation; Dreams; Humans; Methylphenidate; Middle | 1980 |
Daytime sleep in myotonic dystrophy is not caused by sleep apnoea.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methylphenidate; Middle Aged; Myotonic Dystrophy; Pol | 1994 |