methylphenidate has been researched along with Antisocial Behavior in 14 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Antisocial Behavior: Behavior that sharply deviates from social norms and violates rights of others
| Excerpt | Relevance | Reference |
|---|---|---|
| "Covert antisocial behaviors such as stealing, destroying property, and cheating carry high risk for delinquency." | 6.67 | Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: external validation and effects of methylphenidate. ( Heller, T; Hinshaw, SP; McHale, JP, 1992) |
| "Two hospitalized patients with antisocial personality disorder (by DSM-III) and histories of childhood attention deficit disorder became less aggressive during trials of methylphenidate." | 5.27 | Methylphenidate in the treatment of aggression in two patients with antisocial personality disorder. ( Josef, NC; Stringer, AY, 1983) |
| "Covert antisocial behaviors such as stealing, destroying property, and cheating carry high risk for delinquency." | 2.67 | Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: external validation and effects of methylphenidate. ( Heller, T; Hinshaw, SP; McHale, JP, 1992) |
| "Comorbid antisocial personality disorder was a negative predictor of long CS treatment duration." | 1.38 | Predictive factors for more than 3 years' duration of central stimulant treatment in adult attention-deficit/hyperactivity disorder: a retrospective, naturalistic study. ( Gjervan, B; Nordahl, HM; Rasmussen, K; Torgersen, T, 2012) |
| "Two hospitalized patients with antisocial personality disorder (by DSM-III) and histories of childhood attention deficit disorder became less aggressive during trials of methylphenidate." | 1.27 | Methylphenidate in the treatment of aggression in two patients with antisocial personality disorder. ( Josef, NC; Stringer, AY, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Masi, G | 1 |
| Fantozzi, P | 1 |
| Muratori, P | 1 |
| Bertolucci, G | 1 |
| Tacchi, A | 1 |
| Villafranca, A | 1 |
| Pfanner, C | 1 |
| Cortese, S | 1 |
| Newcorn, JH | 1 |
| Blader, JC | 1 |
| Pliszka, SR | 1 |
| Kafantaris, V | 1 |
| Foley, CA | 1 |
| Crowell, JA | 1 |
| Carlson, GA | 1 |
| Sauder, CL | 1 |
| Margulies, DM | 1 |
| Sinha, C | 1 |
| Sverd, J | 1 |
| Matthews, TL | 1 |
| Bailey, BY | 1 |
| Daviss, WB | 1 |
| Sharpe, K | 1 |
| Torgersen, T | 1 |
| Gjervan, B | 1 |
| Nordahl, HM | 1 |
| Rasmussen, K | 1 |
| Klar, H | 1 |
| Siever, LJ | 1 |
| Stringer, AY | 1 |
| Josef, NC | 1 |
| Satterfield, JH | 1 |
| Cantwell, DP | 1 |
| Satterfield, BT | 1 |
| Wood, DR | 1 |
| Reimherr, FW | 1 |
| Wender, PH | 1 |
| Johnson, GE | 1 |
| Leichner, PP | 1 |
| Janowsky, DS | 1 |
| Reid, AE | 1 |
| Hinshaw, SP | 1 |
| Heller, T | 1 |
| McHale, JP | 1 |
| Hechtman, L | 1 |
| Evans, RW | 1 |
| Gualtieri, CT | 1 |
| Hicks, RE | 1 |
| Van Osdol, BM | 1 |
| Carlson, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-Blind, Placebo-Controlled Trial of Flexible Dose Divalproex Sodium Adjunctive to Stimulant Treatment for Aggressive Children With Attention-Deficit Hyperactivity Disorder[NCT00228046] | Phase 4 | 40 participants (Anticipated) | Interventional | 2004-01-31 | Completed | ||
| Adjunctive Treatment With Divalproex or Risperidone for Aggression Refractory to Stimulant Monotherapy Among Children With ADHD[NCT00794625] | Phase 4 | 270 participants (Anticipated) | Interventional | 2008-11-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for methylphenidate and Antisocial Behavior
| Article | Year |
|---|---|
The psychopharmacologic treatment of personality disorders.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Antisocial Personality Diso | 1984 |
Adolescent outcome of hyperactive children treated with stimulants in childhood: a review.
Topics: Achievement; Adolescent; Amphetamine; Antisocial Personality Disorder; Attention Deficit Disorder wi | 1985 |
A study of developmental hyperactivity.
Topics: Aggression; Antisocial Personality Disorder; Attention; Behavior Therapy; Child; Child Behavior Diso | 1972 |
3 trials available for methylphenidate and Antisocial Behavior
| Article | Year |
|---|---|
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Callous-unemotional traits, proactive aggression, and treatment outcomes of aggressive children with attention-deficit/hyperactivity disorder.
Topics: Adolescent; Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior D | 2013 |
Diagnosis and treatment of minimal brain dysfunction in adults: a preliminary report.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Anxiety; Attention Deficit Disorder with Hyperac | 1976 |
Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: external validation and effects of methylphenidate.
Topics: Antisocial Personality Disorder; Attention; Attention Deficit Disorder with Hyperactivity; Child; Co | 1992 |
8 other studies available for methylphenidate and Antisocial Behavior
| Article | Year |
|---|---|
Emotional dysregulation and callous unemotional traits as possible predictors of short-term response to methylphenidate monotherapy in drug-naïve youth with ADHD.
Topics: Adolescent; Antisocial Personality Disorder; Attention Deficit Disorder with Hyperactivity; Central | 2020 |
Can children with callous and unemotional traits be treated successfully?
Topics: Aggression; Antisocial Personality Disorder; Attention Deficit and Disruptive Behavior Disorders; Ce | 2013 |
Medication: the smart-pill oversell.
Topics: Achievement; Antisocial Personality Disorder; Attention; Attention Deficit Disorder with Hyperactivi | 2014 |
Predictive factors for more than 3 years' duration of central stimulant treatment in adult attention-deficit/hyperactivity disorder: a retrospective, naturalistic study.
Topics: Adult; Age Factors; Antisocial Personality Disorder; Attention Deficit Disorder with Hyperactivity; | 2012 |
Methylphenidate in the treatment of aggression in two patients with antisocial personality disorder.
Topics: Adult; Aggression; Antisocial Personality Disorder; Humans; Male; Methylphenidate | 1983 |
Multimodality treatment. A one-year follow-up of 84 hyperactive boys.
Topics: Achievement; Antisocial Personality Disorder; Child; Follow-Up Studies; Humans; Hyperkinesis; Intell | 1979 |
Intravenous methylphenidate as a diagnostic and psychotherapeutic instrument in adult psychiatry.
Topics: Abreaction; Adult; Alcoholism; Antisocial Personality Disorder; Anxiety; Defense Mechanisms; Depress | 1976 |
A neuropathic substrate for stimulant drug effects in hyperactive children.
Topics: Antisocial Personality Disorder; Arousal; Attention Deficit Disorder with Hyperactivity; Child; Corp | 1986 |