methylphenidate has been researched along with Alcohol Drinking in 12 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate (MPH) is a stimulant prescribed to treat attention-deficit/ hyperactivity disorder." | 1.40 | Chronic methylphenidate treatment during early life is associated with greater ethanol intake in socially isolated rats. ( Beveridge, TJ; Chappell, AM; Gill, KE; Porrino, LJ; Weiner, JL, 2014) |
| "Treatment with methylphenidate at an early age (P21 to P35) did not alter ethanol consumption in adult SHR or WKY, suggesting that it does not increase susceptibility to ethanol addiction in these rats." | 1.35 | Methylphenidate does not increase ethanol consumption in a rat model for attention-deficit hyperactivity disorder-the spontaneously hypertensive rat. ( Howells, FM; Russell, VA; Soeters, HS, 2008) |
| "Ethylphenidate was recently reported as a novel drug metabolite in two overdose fatalities where there was evidence of methylphenidate and ethanol coingestion." | 1.31 | Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol. ( Boulton, DW; DeVane, CL; Diamond, F; Markowitz, JS; Nahas, Z; Patrick, KS; Risch, SC, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruiz, P | 1 |
| Calliari, A | 1 |
| Genovese, P | 1 |
| Scorza, C | 1 |
| Pautassi, RM | 1 |
| Scholz, I | 1 |
| Schmid, Y | 1 |
| Exadaktylos, AK | 1 |
| Haschke, M | 1 |
| Liechti, ME | 1 |
| Liakoni, E | 1 |
| Gill, KE | 1 |
| Chappell, AM | 1 |
| Beveridge, TJ | 1 |
| Porrino, LJ | 1 |
| Weiner, JL | 1 |
| Barkla, XM | 1 |
| McArdle, PA | 1 |
| Newbury-Birch, D | 1 |
| Soeters, HS | 1 |
| Howells, FM | 1 |
| Russell, VA | 1 |
| Griffin, WC | 1 |
| Novak, AJ | 1 |
| Middaugh, LD | 1 |
| Patrick, KS | 3 |
| ROGERS, LL | 1 |
| PELTON, RB | 1 |
| Vendruscolo, LF | 1 |
| Izídio, GS | 1 |
| Takahashi, RN | 1 |
| Ramos, A | 1 |
| Hartley, LR | 1 |
| Volkow, ND | 1 |
| Wang, GJ | 1 |
| Fowler, JS | 1 |
| Logan, J | 1 |
| Hitzemann, R | 1 |
| Ding, YS | 1 |
| Pappas, N | 1 |
| Shea, C | 1 |
| Piscani, K | 1 |
| Markowitz, JS | 2 |
| Logan, BK | 1 |
| Diamond, F | 2 |
| DeVane, CL | 1 |
| Boulton, DW | 1 |
| Nahas, Z | 1 |
| Risch, SC | 1 |
1 review available for methylphenidate and Alcohol Drinking
| Article | Year |
|---|---|
Are there any potentially dangerous pharmacological effects of combining ADHD medication with alcohol and drugs of abuse? A systematic review of the literature.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Alcohol Drinking; Atomoxetine Hydrochloride; Attention Def | 2015 |
11 other studies available for methylphenidate and Alcohol Drinking
| Article | Year |
|---|---|
Amphetamine, but not methylphenidate, increases ethanol intake in adolescent male, but not in female, rats.
Topics: Alcohol Drinking; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervo | 2018 |
Emergency department presentations related to abuse of prescription and over-the-counter drugs in Switzerland: time trends, sex and age distribution.
Topics: Adolescent; Adult; Age Distribution; Aged; Alcohol Drinking; Antidepressive Agents; Benzodiazepines; | 2019 |
Chronic methylphenidate treatment during early life is associated with greater ethanol intake in socially isolated rats.
Topics: Age Factors; Alcohol Drinking; Animals; Central Nervous System Stimulants; Choice Behavior; Male; Me | 2014 |
Methylphenidate does not increase ethanol consumption in a rat model for attention-deficit hyperactivity disorder-the spontaneously hypertensive rat.
Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Sti | 2008 |
The interactive effects of methylphenidate and ethanol on ethanol consumption and locomotor activity in mice.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Etha | 2010 |
Effect of behavior-altering drugs on alcohol consumption by rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Methylphenidate; Piperidines; Rats; Tranquilizing Agents | 1958 |
Chronic methylphenidate treatment during adolescence increases anxiety-related behaviors and ethanol drinking in adult spontaneously hypertensive rats.
Topics: Age Factors; Aging; Alcohol Drinking; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cent | 2008 |
Arousal, temporal and spatial uncertainty and drug effects.
Topics: Adult; Alcohol Drinking; Amphetamine; Antipsychotic Agents; Arousal; Attention; Attention Deficit Di | 1983 |
Decreases in dopamine receptors but not in dopamine transporters in alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Brain; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum; | 1996 |
Detection of the novel metabolite ethylphenidate after methylphenidate overdose with alcohol coingestion.
Topics: Adult; Alcohol Drinking; Dose-Response Relationship, Drug; Drug Overdose; Drug Synergism; Female; Ga | 1999 |
Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol.
Topics: Adult; Alcohol Drinking; Analysis of Variance; Central Nervous System Stimulants; Dose-Response Rela | 2000 |